TW202020146A - 含nef之t細胞及其產生方法 - Google Patents

含nef之t細胞及其產生方法 Download PDF

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TW202020146A
TW202020146A TW108126647A TW108126647A TW202020146A TW 202020146 A TW202020146 A TW 202020146A TW 108126647 A TW108126647 A TW 108126647A TW 108126647 A TW108126647 A TW 108126647A TW 202020146 A TW202020146 A TW 202020146A
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nef
tcr
mutant
domain
cell
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TW108126647A
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English (en)
Chinese (zh)
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曉虎 范
趙云程
俞大偉
支武吉南
王趁趁
莊秋傳
王平豔
郭璇璇
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大陸商南京傳奇生物科技有限公司
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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TW108126647A 2018-07-26 2019-07-26 含nef之t細胞及其產生方法 TW202020146A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2018097235 2018-07-26
WOPCT/CN2018/097235 2018-07-26

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TW202020146A true TW202020146A (zh) 2020-06-01

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US (1) US20220177524A1 (https=)
EP (1) EP3827075A4 (https=)
JP (1) JP2021532742A (https=)
KR (1) KR20210049806A (https=)
CN (2) CN112771154B (https=)
AU (1) AU2019312411A1 (https=)
CA (1) CA3103337A1 (https=)
IL (1) IL280240A (https=)
MX (1) MX2021000934A (https=)
SG (1) SG11202012253WA (https=)
TW (1) TW202020146A (https=)
WO (1) WO2020020359A1 (https=)

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US9273283B2 (en) * 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
WO2021180665A1 (en) * 2020-03-09 2021-09-16 Janssen Pharmaceutica Nv Compositions and methods for quantifying integration of recombinant vector nucleic acid
WO2022116086A1 (en) * 2020-12-03 2022-06-09 Janssen Biotech, Inc. Bcma-targeted car-t cell therapy for multiple myeloma
IL304904A (en) * 2021-02-01 2023-10-01 St Phi Therapeutics Co Ltd Target protein degradation system and its use
WO2022198027A1 (en) * 2021-03-18 2022-09-22 The Wistar Institute Of Anatomy And Biology DNA-ENCODED BISPECIFIC ANTIBODIES TARGETING IL13Rα2 AND METHODS OF USE IN CANCER THERAPEUTICS
EP4378952A4 (en) * 2021-07-30 2025-09-24 St Phi Therapeutics Co Ltd UNIVERSAL T LYMPHOCYTE AND ITS USE
WO2023077343A1 (en) * 2021-11-04 2023-05-11 Janssen Biotech, Inc. Bcma-targeted car-t cell therapy for multiple myeloma
WO2023081752A1 (en) * 2021-11-04 2023-05-11 Janssen Biotech, Inc. Bcma-targeted car-t cell therapy for multiple myeloma
EP4561628A1 (en) * 2022-07-29 2025-06-04 Legend Biotech Ireland Limited Methods for promoting persistence of cell therapy
EP4612168A1 (en) * 2022-11-04 2025-09-10 Wugen, Inc. Generation of cd3 expressing immune cells for use in conjunction with cd3 binding bispecific targeting agents
WO2024153211A1 (en) * 2023-01-19 2024-07-25 Nanjing Legend Biotech Co., Ltd. Fusion polypeptides for targeted protein degradation and mehtods of use thereof

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EP2292772A1 (en) * 2001-07-05 2011-03-09 Novartis Vaccines and Diagnostics, Inc. HIV vaccination with a DNA encoding a HIV polypeptide and a HIV polypeptide
CN101027084B (zh) * 2004-08-17 2012-02-22 古斯达威罗斯研究所 用于调节免疫的突变型hiv nef
US9273283B2 (en) * 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
KR102437522B1 (ko) * 2012-05-25 2022-08-26 셀렉티스 면역요법을 위한 동종이형 및 면역억제제 저항성인 ｔ 세포의 조작 방법
CN106459990B (zh) * 2014-02-07 2021-06-01 麦克马斯特大学 三功能t细胞抗原偶联物及其制备方法和用途
LT3134432T (lt) * 2014-04-25 2020-04-10 Bluebird Bio, Inc. Mnd promotorius chimerinių antigenų receptoriams
EA201891641A1 (ru) * 2016-01-21 2019-01-31 Пфайзер Инк. Химерные антигенные рецепторы, нацеленные на вариант iii рецептора эпидермального фактора роста
CN109415687A (zh) * 2016-04-07 2019-03-01 蓝鸟生物公司 嵌合抗原受体t细胞组合物
EP3512950A1 (en) * 2016-09-14 2019-07-24 Benitec Biopharma Limited REAGENTS FOR PRODUCING T-CELLS WITH NON-FUNCTIONAL T-CELL RECEPTORS (TCRs) COMPOSITIONS COMPRISING SAME AND USE THEREOF
CN110520524A (zh) * 2017-04-14 2019-11-29 综合医院公司 靶向肿瘤微环境的嵌合抗原受体t细胞
BR112019021857A2 (pt) * 2017-04-19 2020-06-02 Allogene Therapeutics, Inc. Métodos e composições de célula t aperfeiçoada

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IL280240A (en) 2021-03-25
EP3827075A4 (en) 2022-08-03
KR20210049806A (ko) 2021-05-06
US20220177524A1 (en) 2022-06-09
AU2019312411A1 (en) 2021-01-07
CN112771154B (zh) 2025-01-03
SG11202012253WA (en) 2021-01-28
WO2020020359A1 (en) 2020-01-30
JP2021532742A (ja) 2021-12-02
MX2021000934A (es) 2021-05-27
CN112771154A (zh) 2021-05-07
EP3827075A1 (en) 2021-06-02
CA3103337A1 (en) 2020-01-30
CN119661659A (zh) 2025-03-21

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