TW202019441A - 用於經口遞送寡核苷酸之方法 - Google Patents
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- TW202019441A TW202019441A TW108125529A TW108125529A TW202019441A TW 202019441 A TW202019441 A TW 202019441A TW 108125529 A TW108125529 A TW 108125529A TW 108125529 A TW108125529 A TW 108125529A TW 202019441 A TW202019441 A TW 202019441A
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- modified
- nucleoside
- modified oligonucleotide
- certain embodiments
- compound
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/35—Special therapeutic applications based on a specific dosage / administration regimen
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
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- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862701317P | 2018-07-20 | 2018-07-20 | |
| US62/701,317 | 2018-07-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW202019441A true TW202019441A (zh) | 2020-06-01 |
Family
ID=67704556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW108125529A TW202019441A (zh) | 2018-07-20 | 2019-07-19 | 用於經口遞送寡核苷酸之方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220098581A1 (https=) |
| EP (1) | EP3824087A1 (https=) |
| JP (1) | JP2021531278A (https=) |
| CN (1) | CN112424356A (https=) |
| TW (1) | TW202019441A (https=) |
| WO (1) | WO2020018887A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4282964A1 (en) * | 2022-05-23 | 2023-11-29 | Universitat de Valéncia | Oligonucleotides conjugated to oleic acid and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1120707C (zh) | 1995-11-22 | 2003-09-10 | 约翰斯·霍普金斯大学 | 增强生物分子的细胞摄取的配体 |
| US7491805B2 (en) | 2001-05-18 | 2009-02-17 | Sirna Therapeutics, Inc. | Conjugates and compositions for cellular delivery |
| WO2009073809A2 (en) | 2007-12-04 | 2009-06-11 | Alnylam Pharmaceuticals, Inc. | Carbohydrate conjugates as delivery agents for oligonucleotides |
| SI2539451T1 (sl) | 2010-02-24 | 2016-04-29 | Arrowhead Research Corporation | Sestavki za ciljano dostavo sirna |
| EP2561102A1 (en) * | 2010-12-02 | 2013-02-27 | Katholieke Universiteit Leuven K.U. Leuven R&D | Irak-related interventions and diagnosis |
| AU2011343664B2 (en) | 2010-12-17 | 2015-10-08 | Arrowhead Pharmaceuticals, Inc. | Galactose cluster-pharmacokinetic modulator targeting moiety for siRNA |
| WO2013033230A1 (en) | 2011-08-29 | 2013-03-07 | Isis Pharmaceuticals, Inc. | Oligomer-conjugate complexes and their use |
| US9506030B2 (en) * | 2013-05-01 | 2016-11-29 | Regulus Therapeutics Inc. | Compounds and methods for enhanced cellular uptake |
| SG10201803157XA (en) * | 2013-05-01 | 2018-05-30 | Regulus Therapeutics Inc | Microrna compounds and methods for modulating mir-122 |
| KR20170033439A (ko) * | 2014-08-07 | 2017-03-24 | 레굴루스 테라퓨틱스 인크 | 대사 장애에 대한 마이크로rna의 표적화 |
-
2019
- 2019-07-19 JP JP2021502604A patent/JP2021531278A/ja active Pending
- 2019-07-19 TW TW108125529A patent/TW202019441A/zh unknown
- 2019-07-19 WO PCT/US2019/042561 patent/WO2020018887A1/en not_active Ceased
- 2019-07-19 EP EP19756448.7A patent/EP3824087A1/en not_active Withdrawn
- 2019-07-19 CN CN201980048096.XA patent/CN112424356A/zh active Pending
- 2019-07-19 US US17/259,366 patent/US20220098581A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020018887A1 (en) | 2020-01-23 |
| US20220098581A1 (en) | 2022-03-31 |
| CN112424356A (zh) | 2021-02-26 |
| EP3824087A1 (en) | 2021-05-26 |
| JP2021531278A (ja) | 2021-11-18 |
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