TW201600069A - Cooling patch - Google Patents

Abstract

The present invention relates to a cooling patch capable of excellently maintaining the cooling effect from using the vaporization heat of water, and unleashing a continuous high cooling effect. The cooling patch of this invention is made by laminating an aqueous polymer gel (A) and a fiber sheet (B), wherein the aqueous polymer gel (A) has a water content of 65 mass% or more and 95 mass% or less, and the fiber sheet (B) has a thickness of 0.001mm or more and 1mm or less, and a basis weight of 3g/m2 or more and 70g/m2 or less, and a water absorption test value of 1 to 16,000 seconds, and the patch has a water content of 585g/m2 or more and 1700g/m2 or less.

Description

Cooling patch

The present invention relates to a cooling patch.

Previously, a cooling adhesive tape in which a non-woven fabric and a water-containing polymer gel layer were laminated was known. It is known that when a cooling adhesive is applied to the skin, the side of the aqueous polymer gel layer is brought into contact with the skin, whereby the partial cooling effect is exerted by the vaporization heat of water. The cooling adhesive tape comprises a fibrous layer of a non-woven fabric or a woven fabric having a thickness of about 100 g/m ² and an aqueous gel layer mainly composed of polyacrylic acid or a polyacrylic acid derivative, and is also tried to improve the cooling performance. It is also desired to increase the thickness of the aqueous gel layer in order to increase the water content of the glue or to improve the cooling durability (for example, Non-Patent Documents 1 and 2).

In recent years, various improvements have been made to such a cooling adhesive tape. For example, Patent Document 1 discloses an adhesive comprising a layer of an aqueous adhesive layer and a fibrous sheet comprising hydrophobic fibers having a specific basis weight and thickness, which reduces the viscosity during use and achieves a cooling effect. Improve. Further, Patent Document 2 discloses a sheet-like patch comprising a sheet-like support and an adhesive layer having a specific basis weight and a mixture of enamel and pulp, by supporting the body surface and the adhesive surface. The overlap and subsequent tensile shearing are then set to a specific range to bring about cooling, and to prevent peeling of overlapping portions during use.

On the other hand, it is known that the cooling feeling generated when the cooling sheet is attached to the skin is more likely to be felt as the skin temperature of the average elapsed time is changed (Non-Patent Document 3). Therefore, when the skin temperature of the patch attachment portion rises, or the same skin is maintained for a certain period of time In the case of temperature, the possibility of coldness is high.

(Patent Document 1) Japanese Patent Laid-Open Publication No. 2004-33279

(Patent Document 2) International Publication No. 2002/100384

(Non-Patent Document 1) Goto, et al., "Chemical Engineering", Vol. 76, No. 9, 2012

(Non-Patent Document 2) Nikken Akira, "From Functional Nonwovens - Raw Material Development to Industrial Use -", CMC Publishing, 2004

(Non-Patent Document 3) Hensel et al., "Thermoreception and temperature regulation", Academic Press, 1981

The present invention relates to a cooling patch which is obtained by laminating a water-containing polymer gel (A) and a fiber sheet (B): (A) a water content of 65 mass% or more and 95 mass% or less. a molecular gel, and (B) a fiber sheet having a thickness of 0.001 mm or more and 1 mm or less, a basis weight of 3 g/m ² or more and 70 g/m ² or less, and a water absorption test value of 1 to 16000 seconds, and the patch The water content is 585 g/m ² or more and 1700 g/m ² or less.

In the context of the development of the above various types of cooling adhesives, it is expected that a cooling adhesive effect which provides a continuous cooling effect can be achieved not only by the temporary cooling effect. However, in the patch described in Patent Document 1, since the hydrophobic fibers do not sufficiently absorb the moisture of the hydrogel layer, vaporization of water is insufficient, and the cooling effect by the heat of vaporization tends to be weak. Moreover, even if it is the sheet-like patching agent of the above-mentioned patent document 2, there is still room for improvement when the cooling effect is fully improved.

Therefore, the present inventors have made an effort to solve the above problems, and as a result, as a fiber sheet, a fiber sheet having a specific thickness, a basis weight, and a water absorption test value in a specific range has been used, and it has a high water content. The water-containing polymer gel is laminated to form a cooling patch which maintains a high moisture content as a whole, thereby promoting the transfer of moisture from the gel to the fiber sheet, and the evaporation of moisture from the fiber sheet, and the attachment portion of the sheet. Temperature holding Continued reduction, long-term bring a good sense of coolness; thus completing the present invention.

According to the present invention, a large amount of water contained in the aqueous polymer gel is favorably transferred to the fiber sheet, and the fiber sheet is efficiently and continuously evaporated from the fiber sheet, so that the vaporization heat of water can be effectively utilized for a long period of time, so that the coldness is good. The sense continues. Therefore, in a high-temperature and high-humidity environment in which the vaporization heat of water becomes small and the cooling effect is easily weakened, a high cooling effect can be exhibited. Moreover, according to the present invention, excessive moisture is prevented from staying in the fiber sheet, so that a comfortable cold feeling can be maintained and a good feeling of use can be actually felt.

Fig. 1 is a view showing changes in skin surface temperature ⊿T ₂ (°C) when the sheets of Examples 1, 3, 5, and 7 and Comparative Examples 5, 8, and 9 were attached to the forehead.

Hereinafter, the present invention will be described in detail.

The cooling patch of the present invention is obtained by laminating a water-containing polymer gel (A) having a specific moisture content in a specific range and a fiber sheet (B) having a basis weight, a thickness and a water absorption property in a specific range described below. The whole has a specific range of water content. At the time of use, the surface of the cooling polymer patch on the side of the aqueous polymer gel is attached to the object. When the cooling patch of the present invention is attached to the skin, heat is transferred from the skin to the aqueous polymer gel (A), and the moisture in the aqueous polymer gel is transferred to the fiber sheet (B), so that the moisture is derived from the fiber. The sheet (B) is evaporated, and the heat supplied from the skin is removed by the heat of vaporization of water, and as a result, the portion to which the sheet is attached is cooled. On the other hand, the fiber sheet (B) laminated on the aqueous polymer gel (A) is continuously transferred from the aqueous polymer gel (A) at a moderate speed as described below, so that the self-fiber sheet can be improved (B). ) The persistence of moisture evapotranspiration and the long-lasting cooling sensation.

The water content in the aqueous polymer gel (A) constituting the cooling patch of the present invention is 65 mass% or more, preferably 66, from the viewpoint of continuously cooling the sheet attaching portion by the heat of vaporization of water. The mass% or more is more preferably 68% by mass or more, and still more preferably 70% by mass or more. From the same viewpoint, the aqueous polymer constituting the cooling patch of the present invention The water content in the gel (A) is 95% by mass or less, preferably 93% by mass or less, and more preferably 92% by mass or less. Further, the water content of the aqueous polymer gel constituting the cooling patch of the present invention is 65 to 95% by mass, preferably 66 to 93% by mass, more preferably 68 to 92% by mass, still more preferably 70. ~92% by mass. The amount of water that can be the moisture content is formulated in the gel stock solution.

In addition, the water content of the aqueous polymer gel (A) can be measured using a moisture meter using a Karl Fischer method (for example, the Aomori automatic moisture measuring device AQV-300 series).

It also has a layer of aqueous polymer gel (A) from the viewpoint of the interaction between the following fiber sheets, the continuous transfer of sufficient water content to the fiber sheet, and the prevention of heat storage when attached to the skin. It is preferably an amount of 615g / m ² or more, more preferably 650g / m ² or more, and further preferably from 670g / m ² or more, and further preferably in particular, 700g / m ² or more. On the same viewpoint, the aqueous polymer gel (A) is preferably an amount of layered 2600g / m ² or less, more preferably 2200g / m ² or less, and further preferably 2000g / m ² or less, and further preferably in particular, It is 1400 g/m ² or less. Further, the aqueous polymer gel (A) is preferably an amount of laminate 615 ~ 2600g / m ^2, more preferably 650 ~ 2200g / m ^2, further preferably 670 ~ 2000g / m ^2, further preferably in particular 700 ~1400g/m ² . Further, the amount of the layer of the aqueous polymer gel (A) means the amount in the stock solution.

The polymer which forms the aqueous polymer gel (A) may be a gel which retains water and forms moderate elasticity or flexibility, and examples thereof include a polymer having a functional group such as a carboxyl group, a sulfate group or a phosphate group. . Specific examples of the polymer include poly(meth)acrylic acid or a salt thereof such as a carboxyvinyl polymer, polyacrylic acid or a salt thereof, or an acrylic acid-alkyl methacrylate copolymer; carboxymethylcellulose or a salt thereof An anionic cellulose derivative such as carboxyethyl cellulose or a salt thereof; gellan gum, pectin, celestial gum, carrageenan, agar, alginic acid and salts thereof, anionic starch derivative, etc. One or two or more of these polymers are used. Among them, it has the advantages of high water retention capacity, sufficient gel strength, and the ability to follow the unevenness of the skin or the softness of its action, and to supply more water to the fiber sheet. From the viewpoint of (B), it is preferably one or more selected from the group consisting of poly(meth)acrylic acid or a salt thereof, an anionic cellulose derivative, and carrageenan, and more preferably selected from polyacrylic acid. One or two or a salt thereof, and carboxymethylcellulose or a salt thereof is further preferably carboxymethylcellulose or a salt thereof. It also interacts with the action of the fiber sheet (B) described below, and in the viewpoint of continuously transferring sufficient water content to the fiber sheet (B), in the polymer-containing aqueous polymer gel (A) The content is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, and still more preferably 1% by mass or more. From the same viewpoint, the content of the polymer is preferably 30% by mass or less, more preferably 20% by mass or less, further preferably 15% by mass or less, and particularly preferably 12% by mass or less. Further, the content of the polymer-containing aqueous polymer gel (A) is preferably from 0.1 to 30% by mass, more preferably from 0.5 to 20% by mass, still more preferably from 1 to 15% by mass, particularly preferably further preferably. It is 1 to 12% by mass. It can be blended in a stock solution of a water-containing polymer gel in such a manner as to be a polymer content.

When the aqueous polymer gel (A) is formed from the above polymer, a crosslinking agent can be further used to react with a functional group of the polymer. Examples of the crosslinking agent include oxides, hydroxides or salts selected from metal ions such as aluminum, magnesium, titanium, chromium, manganese, iron, cobalt, nickel, zinc, cadmium, lead, calcium, and potassium. a cationic polymer such as polyamino acid such as polyaminic acid; polyfunctionality such as ethylene glycol diglycidyl ether, polyethylene glycol diglycidyl ether, glycerol diglycidyl ether, and glycerol triglycidyl ether; One or more of the epoxy compounds.

Further, from the viewpoint of actually feeling a high cooling feeling, the aqueous polymer gel (A) preferably contains a cooling agent as needed. Thereby, the cooling feeling can be further increased. Therefore, it is suitable to use the cooling patch of the present invention in a case where a higher cooling feeling is desired in a high-temperature and high-humidity environment such as summer.

The cooling agent may be any agent which brings a feeling of coolness and refreshment. Specific examples thereof include l-menthol, d-menthol, dl-menthol, cineole, menthanediol, and menthyl lactate. , l-menthol glyceryl ether, menthyl ethyl amino oxalic acid, menthyl pyrrolidone Carboxylic acid, menthyl succinate, menthyl glutarate, ethyl menthyl formamide, ethyl menthane carbonyl glycinate, menthone, menthone glycerol acetal, 2-t-butylcyclohexanone , isoamyl menthol, menthol, N, 2,3-trimethyl-2-isopropylbutanamine, thymol, eugenol, aniseed brain, methyl salicylate, camphor, flower chrysanthemum Alcohol, trimethylcyclohexanol, 3-l-menthyloxy-2-methylpropane-1,2-diol, and the like. Further, an essential oil containing the above substances may be used, and examples thereof include peppermint oil, peppermint oil, spearmint oil, eucalyptus oil, sassafras oil, and wintergreen. These may be used alone or in combination of two or more. Among them, from the viewpoint of suppressing skin irritation and bringing about a good odor, it is preferably selected from the group consisting of l-menthol, menthyl lactate, l-menthyl glyceryl ether, menthyl ethyl amino oxalic acid, and menthane carbonyl. One or more of ethyl glycinate, iso-menthol menthol, and camphor, and more preferably one selected from the group consisting of l-menthol, menthyl lactate, menthyl ethyl oxalic acid, and camphor Or two or more types, and further preferably, one or two types selected from the group consisting of l-menthol and menthyl lactate.

In the aqueous polymer gel (A), the content of the sensitizer is preferably 0.0001% by mass or more, more preferably 0.001% by mass or more, and still more preferably 0.005% by mass or more. Further, from the viewpoint of suppressing irritation, it is preferably 10% by mass or less, more preferably 5% by mass or less, and still more preferably 1% by mass or less. The content may be adjusted to the original solution of the aqueous polymer gel, or may not be substantially contained. Further, the content of the cooling agent is preferably 0.0001 to 10% by mass, more preferably 0.001 to 5% by mass, still more preferably 0.005 to 1% by mass, based on the aqueous polymer gel (A). The cooling patch of the present invention can continuously reduce the temperature of the patch attachment portion and continuously bring about a good cold feeling, so that even if the content of the cooling agent is low, even if it is substantially not contained, it can be fully and practically sustainable. Feel the cold feeling.

The pH of the aqueous polymer gel (A) is preferably from 3.5 to 7. Usually, the pH value of the normal skin of a person is within the above range, and if the pH value of the skin changes beyond the need, the function of the skin is hindered, so the pH of the aqueous polymer gel which is directly in contact with the skin is preferred. The value is also in the above range. This pH can be adjusted by using an appropriate pH adjuster. As the pH adjuster, for example, an organic acid such as succinic acid, citric acid or tartaric acid or a salt thereof, or phosphoric acid or a salt thereof is preferably used. The pH of the aqueous polymer gel (A) is more preferably 4 to 7, more preferably 4 to 6.5.

Further, the pH of the aqueous polymer gel (A) was mixed and stirred until 0.5 g of the aqueous polymer gel was dissolved in 4.5 g of pure water, and dispersed by a pH meter (B-212, HORIBA). The pH of the liquid is measured and obtained.

In the aqueous polymer gel (A), in addition to the above components, other components used in cosmetics, pharmaceuticals, and the like may be appropriately contained, for example, a moisturizing agent, an oil agent, an anionic surfactant, a cationic surfactant, or the like. Surfactant such as amphoteric surfactant, nonionic surfactant; medicinal ingredient; preservative; antioxidant; ultraviolet absorber; solvent; coloring material; "Synthetic fragrance chemistry and commodity knowledge", Yin Tengyuan, 1996 "Chemical Industry Daily", "Perfume and Flavor Chemicals", STEFFENARCTAMDER, and other fragrances such as the cold sensitizers described in the literature in 1969. Among these components, a humectant preferably contains a polyhydric alcohol such as glycerin, diglycerin, polyglycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol or polyethylene glycol. Moreover, these components may be contained in the fiber sheet (B).

In order to produce the aqueous polymer gel (A), first, an aqueous polymer gel stock solution containing a polymer, water, and, if necessary, a cold sensitizer or other components is prepared. Then, the aqueous polymer gel stock solution was poured into the peelable film, and stretched using a Baker-type applicator or the like. At this time, one side of the gel raw liquid may be set as a fiber sheet. Then, the aqueous polymer gel (A) is obtained by curing it at room temperature or at a temperature of 35 to 60 ° C for several hours to several days. Further, the aqueous polymer gel (A) can be produced according to a conventionally known method, and is not limited to the above-described production method.

Examples of the method for laminating the aqueous polymer gel (A) and the fiber sheet (B) include a method of forming a surface of the gel stock solution into a fiber sheet (B); or coating the release film. After the cloth gel stock solution, the fiber sheets are overlapped and pressed to laminate; once the aqueous polymer gel (A) is prepared, the water-based polymer gel (A) is applied to the fiber sheet (B), and pressed and laminated. . Alternatively, it may be a form in which the water-containing polymer gel (A) obtained is attached to the skin and then covered with the fiber sheet (B).

The fiber sheet (B) constituting the cooling patch of the present invention preferably contains water-absorbent fibers. Specific examples of the water-absorbent fiber include water-absorbent fibers such as hydrazine, cotton, copper ammonia, hemp, wool, silk, acetate, cellulose, wood pulp, and non-wood pulp; and having a hydroxyl group and a carboxyl group. a polymer of a hydrophilic group such as a sulfonic acid group, a decylamino group or an amino acid group, such as polyvinyl alcohol, polyethylene glycol, cellulose acetate, polypropylene decylamine, melamine resin, nylon, hydrophilic polyamine group a water-absorbent fiber of a hydrophilic polymer such as a formate; a water-absorbent fiber comprising a hydrophobized polymer such as a polyester which has been subjected to a hydrophilization treatment; and a hydrophobic polymer containing polyethylene or polypropylene The composite fiber of the hydrophobic portion and the water absorbent portion. These may be used alone or in combination of two or more. Examples of the conjugate fiber include fibers having a core-sheath structure including a core portion and a sheath portion. Further, it is also possible to form a porous structure in which a void which retains moisture is formed inside the fiber.

Further, at least a part of each of the water-absorbent fibers may exist in a state in which the alignment is in one direction in the fiber sheet (B), or may be aligned in a random direction.

As a form of the fiber sheet (B) used in the present invention, the transfer of moisture from the aqueous polymer gel to the fiber sheet (B) and the evaporation of water from the fiber sheet (B) are very well promoted. Preferably, it is a nonwoven fabric, a woven fabric, a knitted fabric, or paper containing the fibers. In particular, it is more preferably a fiber sheet containing one or more types of water-absorbent fibers selected from the group consisting of sputum, cotton, copper ammonia, cellulose, pulp, and polyvinyl alcohol, or containing such water-absorbent fibers and hydrophobic fibers. Mixed fiber sheets. More preferably, it is a fiber sheet containing one or more types of water-absorbent fibers selected from the group consisting of cerium, cellulose, pulp, and polyvinyl alcohol, or a mixed fiber sheet containing the water-absorbent fibers and hydrophobic fibers.

The content of the water-absorbent fiber in the fiber sheet (B) is very good in terms of promoting the transfer of water from the water-containing polymer gel (A) to the fiber of the fiber sheet (B) and the evapotranspiration of the water from the fiber. It is preferably 1% by mass or more, more preferably 5% by mass or more, and still more preferably 10% by mass or more. The content of the water absorbent fibers in the fiber sheet (B) is preferably 100% by mass or less. Further, the content of the water-absorbent fiber in the fiber sheet (B) is preferably from 1 to 100% by mass, more preferably from 5 to 100% by mass, still more preferably from 10 to 100% by mass.

The fiber sheet (B) of the present invention has a basis weight of 3 g/m ² or more, and promotes the transfer of moisture from the aqueous polymer gel (A) to the fiber of the fiber sheet (B) and the evapotranspiration of the water from the fiber. From the viewpoint of the above, it is preferably 5 g/m ² or more, more preferably 10 g/m ² or more, and still more preferably 14 g/m ² or more. The fiber sheet (B) of the present invention has a basis weight of 70 g/m ² or less, and is preferably 60 g/m ² or less, more preferably 50 g/m ² or less, still more preferably 40 g/m from the same viewpoint. ² or less. Further, the fiber sheet (B) of the present invention has a basis weight of from 3 to 70 g/m ² , preferably from 5 to 60 g/m ² , more preferably from 10 to 50 g/m ² , still more preferably from 14 to 40 g/m. ² .

The viewpoint of promoting the transfer of moisture from the aqueous polymer gel (A) to the fiber sheet (B) and the evaporation of moisture from the fiber sheet (B) is very good, and the cooling performance of the cooling sheet of the present invention is improved. The fiber density of the fiber sheet (B) is preferably from 30,000 to 1,000,000 g/m ³ , more preferably from 50,000 to 800,000 g/m ³ , still more preferably from 60,000 to 500,000 g/m ³ .

The thickness of the fiber sheet (B) is 0.001 mm or more, preferably 0.005 mm or more, from the viewpoint of not inhibiting the evapotranspiration of the water contained in the aqueous polymer gel (A) and maintaining the effect for a long period of time. It is preferably 0.01 mm or more, and more preferably 0.02 mm or more. From the same viewpoint, the thickness of the fiber sheet (B) is 1 mm or less, preferably 0.8 mm or less, more preferably 0.7 mm or less, still more preferably 0.6 mm or less. Further, the thickness of the fiber sheet is 0.001 to 1 mm, preferably 0.005 to 0.8 mm, more preferably 0.01 to 0.7 mm, still more preferably 0.02 to 0.6 mm.

The thickness of the fiber sheet (B) was measured using a constant pressure thickness measuring instrument (manufactured by PG-11 J-type Teclock Corporation (measuring force: 3.7 g/cm ² , probe diameter: 10 cm ² )).

The fiber sheet (B) is a value obtained by the following test and the water absorption test value is 1 to 16,000 seconds. In addition, the water absorption test value of the present invention is to place a 5×5 cm fiber piece on a cylinder having a diameter of 4 cm, and add 1 drop (about 0.04 mL) of water from a height of 1 cm above the fiber piece to reach the water drop. The value measured in seconds (seconds) after the fiber sheet is reached until it becomes free of specular reflection. After the water was added dropwise, the water absorption test value was not obtained when one or all of the water was transmitted from the side opposite to the side to which the water was dropped. The measurement environment was set to 25 ° C and 40 ± 5% RH. Further, the surface opposite to the side to which the water is added is partially or completely transmitted, meaning that the water dropped is formed on the surface opposite to the side to be dropped.

The above water absorption test is based on the method of the water absorption test by the Byreck method of JIS L1907 (dropping method). The fiber sheet (B) having a value of 16,000 seconds or less obtained by the water absorption test can absorb water well from the aqueous polymer gel, and continuously keeps moisture from contacting the fibrous sheet with the aqueous polymer gel. The surface opposite to the surface is evacuated, so that the long-term cooling effect can be sufficiently exerted. Further, the fiber sheet having a water absorption test value of 1 second or longer can effectively avoid excessive water absorption from the aqueous polymer gel (A), and therefore can also reduce the amount of moisture remaining in the fiber sheet (B) without evapotranspiration. Not only can the adhesiveness of the fiber sheet (B) at the time of use be effectively reduced, but also the continuous moisture evapotranspiration from the surface of the fiber sheet (B) can be further promoted.

The water absorption test value is from 1 to 16,000 seconds, and from the above viewpoint, it is preferably from 1 to 14,000 seconds, more preferably from 1 to 12,000 seconds.

The viewpoint of promoting the transfer of moisture from the aqueous polymer gel (A) to the fiber sheet (B) and the evaporation of moisture from the fiber sheet (B) is very good, and the cooling performance of the cooling sheet of the present invention is improved. The value of the 1/3 power of the water absorption test value of the fiber sheet (B) multiplied by the fiber density is preferably 0.25 × 10 ⁶ to 2.2 × 10 ⁶ seconds ^1/3 ‧ g / m ³ , more preferably 0.5 ×10 ⁶ ~ 2.1 × 10 ⁶ seconds ^1/3 ‧ g / m ³ , further preferably 0.8 × 10 ⁶ ~ 2 × 10 ⁶ seconds ^1/3 ‧ g / m ³ Further, it is considered that the value of the 1/3 power of the water absorption test value multiplied by the fiber density indicates the diffusion speed of water in the fiber sheet (B).

The present invention is cooled by the water content of the patch to 585g / m ² or more, by the heat of vaporization of the cooling water is continuously view the application site of the patch, it is preferably 600g / m ² or more, more preferably 650 g/m ² or more. The moisture content of the cooling patch of the present invention is 1700 g/m ² or less, and is preferably 1600 g/m ² or less, more preferably 1500 g/m ² or less, and still more preferably 1250 g/m from the viewpoint of cooling performance. ² or less.

In addition, the moisture content of the cooling patch of the present invention means that the moisture content of the cooling patch of the present invention after use is obtained by the amount of the layer in the aqueous polymer gel stock solution (g/m). ² ) The value of the water content in the aqueous polymer gel stock solution.

The viewpoint of promoting the transfer of moisture from the aqueous polymer gel (A) to the fiber sheet (B) and the evaporation of moisture from the fiber sheet (B) is very good, and the cooling performance of the cooling sheet of the present invention is improved. The mass ratio of moisture to fiber in the cooling patch for the cooling patch of the present invention (water quality/fiber mass in the cooling patch) is preferably 9 or more, more preferably 15 or more, and further preferably 20 or more, particularly preferably 25 or more. The moisture-to-fiber mass ratio (water quality/fiber quality of the cooling patch) of the cooling patch of the cooling patch of the present invention is preferably 320 or less, and more preferably, from the viewpoint of the cooling performance and the cooling sustainability. It is preferably 150 or less, more preferably 100 or less, and particularly preferably 70 or less. Further, the mass ratio of moisture to fiber of the cooling patch for cooling sheet of the present invention (water quality/fiber quality of the cooling sheet) is preferably from 9 to 320, more preferably from 15 to 150, and further preferably. It is 20 to 100, and particularly preferably 25 to 70.

The cooling patch of the present invention is capable of effectively and continuously cooling the skin by adhering the surface of the aqueous polymer gel (A) opposite to the surface contacting the fiber sheet (B) to the skin. For example, as a cosmetic, a pharmaceutical, a quasi-drug, and a miscellaneous goods to be attached to a skin (including a scalp), the use thereof is various. More specifically, in the case of a sudden fever, if you want to cool the forehead or the front of the neck, you want to cool your limbs, body, neck, face, and head before going to sleep on a hot, hard-to-sleep night in summer. Sense of summer outdoor desire When it is hot and humid, it can be attached to the skin of a desired part and used. In the case of high temperature and high humidity, the temperature is 26° C. or higher and 60° C. or lower, and the relative humidity is 55% or more and 100% or less.

In the above embodiment, the present invention further discloses the following cooling patch.

[1] A cooling patch obtained by laminating a water-containing polymer gel (A) and a fiber sheet (B): (A) an aqueous polymer having a water content of 65 mass% or more and 95 mass% or less The gel and (B) comprise a water-absorbing fiber, a fiber sheet having a thickness of 0.001 mm or more and 1 mm or less, a basis weight of 3 g/m ² or more and 70 g/m ² or less, and a water absorption test value of 1 to 16,000 seconds. and the water content of the patch to 585g / m ² or more and 1700g / m ² or less.

[2] The cooling patch according to the above [1], wherein the water content in the aqueous polymer gel (A) is preferably 66% by mass or more, more preferably 68% by mass or more, and still more preferably 70% by mass. The above is preferably 93% by mass or less, and more preferably 92% by mass or less.

[3] The cooling patch according to the above [1] or [2], wherein the amount of the aqueous polymer gel (A) is preferably 615 g/m ² or more, more preferably 650 g/m ² or more, and further best of 670g / m ² or more, and further preferably in particular, 700g / m ² or more, and, preferably 2600g / m ² or less, more preferably 2200g / m ² or less, and further preferably 2000g / m ² or less, in particular Further, it is preferably 1400 g/m ² or less.

[4] The cooling patch according to any one of the above [1] to [3] wherein the polymer forming the aqueous polymer gel (A) is preferably selected from the group consisting of poly(meth)acrylic acid or a salt thereof. One or two or more kinds of the anionic cellulose derivative and the carrageenan are more preferably one or two selected from the group consisting of polyacrylic acid or a salt thereof, and carboxymethylcellulose or a salt thereof, and further Preferred is carboxymethyl cellulose or a salt thereof.

[5] The cooling patch according to any one of the above [1] to [4] wherein the aqueous polymer gel (A) preferably further contains a cooling agent.

[6] The cooling patch according to any one of the above [1] to [5] wherein the cooling sensitizer is preferably selected from the group consisting of l-menthol, menthyl lactate, l-menthyl glyceryl ether, and menthylethyl One or more selected from the group consisting of amino oxalic acid, ethyl menthane carbonyl glycinate, iso-menthol menthol and camphor, and more preferably selected from the group consisting of l-menthol, menthyl lactate, menthyl ethyl amino oxalic acid and One or two or more kinds of camphor are further preferably one or two selected from the group consisting of l-menthol and menthyl lactate.

[7] The cooling patch according to any one of the above [1] to [6] wherein the content of the cooling agent is preferably 0.0001% by mass or more, more preferably 0.001% by mass or more, based on the aqueous polymer gel. Further, it is preferably 0.005% by mass or more, more preferably 10% by mass or less, still more preferably 5% by mass or less, still more preferably 1% by mass or less.

[8] The cooling patch according to any one of the above [1] to [7] wherein the pH of the aqueous polymer gel (A) is preferably from 3.5 to 7, more preferably from 4 to 7, and further Good for 4~6.5.

[9] The cooling patch according to any one of the above [1] to [8] wherein the form of the fiber sheet (B) is preferably a non-woven fabric.

[10] The cooling patch according to any one of the above [1] to [9] wherein the fiber sheet (B) preferably contains water-absorbent fibers, more preferably a mixed fiber containing water-absorbent fibers and hydrophobic fibers. sheet.

[11] The cooling patch according to any one of the above [1] to [10] wherein the fiber sheet (B) preferably contains one selected from the group consisting of ruthenium, cellulose, pulp, and polyvinyl alcohol or Two or more types of water-absorbent fibers.

[12] The cooling patch according to any one of the above [1] to [11] wherein the content of the water absorbent fibers in the fiber sheet (B) is preferably 1% by mass or more, more preferably 5% by mass or more. Further, it is preferably 10% by mass or more.

[13] The cooling patch according to any one of the above [1] to [12] wherein the basis weight of the fiber sheet (B) is preferably 5 g/m ² or more, more preferably 10 g/m ² or more. It is preferably 14 g/m ² or more, more preferably 60 g/m ² or less, still more preferably 50 g/m ² or less, still more preferably 40 g/m ² or less.

[14] The cooling patch according to any one of the above [1] to [13] wherein the fiber sheet (B) has a fiber density of preferably 30,000 to 1,000,000 g/m ³ , more preferably 50,000 to 800 000 g/m ³ Further preferably, it is 60,000 to 500,000 g/m ³ .

[15] The cooling sheet according to any one of [1] to [14] wherein the thickness of the fiber sheet (B) is preferably 0.005 mm or more, more preferably 0.01 mm or more, and still more preferably 0.02 mm. The above is preferably 0.8 mm or less, more preferably 0.7 mm or less, still more preferably 0.6 mm or less.

[16] The cooling patch according to any one of the above [1] to [15] wherein the water absorption test value of the fiber sheet (B) is preferably from 1 to 14,000 seconds, more preferably from 1 to 12,000 seconds.

[17] The cooling patch according to any one of the above [1] to [16] wherein the water absorption test value of the fiber sheet (B) is placed on a cylinder having a diameter of 4 cm, and a fiber sheet of 5 × 5 cm is placed. A drop of water was dropped from the height of 1 cm above the fiber sheet to measure the time (seconds) required for the water droplets to reach the fiber sheet until the specular reflection became anhydrous.

[18] The cooling patch according to any one of the above [1] to [17] wherein the value of the 1/3 of the water absorption test value of the fiber sheet (B) multiplied by the fiber density is preferably 0.25. ×10 ⁶ to 2.2 × 10 ⁶ seconds ^1/3 ‧ g / m ³ , more preferably 0.5 × 10 ⁶ ~ 2.1 × 10 ⁶ seconds ^1/3 ‧ g / m ³ , further preferably 0.8 × 10 ⁶ ~ 2 ×10 ⁶ seconds ^1/3 ‧ g/m ³ .

[19] The cooling patch according to any one of [1] to [18] wherein the moisture content in the cooling patch is preferably 600 g/m ² or more, more preferably 650 g/m ² or more. It is preferably 1600 g/m ² or less, more preferably 1500 g/m ² or less, still more preferably 1250 g/m ² or less.

[20] The cooling patch according to any one of the above [1] to [19] wherein the mass ratio of moisture to fiber in the cooling patch (water quality/fiber quality of the cooling patch) is preferably 9 or more, more preferably 15 or more, still more preferably 20 or more, particularly preferably 25 or more, further preferably 320 or less, more preferably 150 or less, still more preferably 100 or less, and particularly preferably further 70 or less.

[21] Use of a cooling patch, which is cold as in any one of [1] to [20] above However, for the purpose of the patch, the cooling patch is used for high temperature and humidity.

[22] The use of the cooling patch according to any one of the above [1] to [20], wherein the cooling patch is used for at least 15 after the film is attached. The temperature of the attached portion of the sheet is continuously lowered in minutes.

[23] The cooling patch according to any one of the above [1] to [20] wherein the aqueous polymer gel (A) is attached to the surface opposite to the surface contacting the fiber sheet (B). Used to cool the skin on the skin.

[24] A cooling method using the cooling patch according to any one of [1] to [20] above, wherein the temperature of the sheet attaching portion is continuously lowered after the sheet is attached for at least 15 minutes.

[Examples]

Hereinafter, the present invention will be specifically described based on examples, but the present invention is not limited to the examples.

[Test Example 1: Measurement of water absorption test value of fiber sheet]

The water absorption test values of the fiber sheets of Reference Examples 1 to 13 shown below were measured by the following methods. Specifically, a 5×5 cm fiber piece was placed on a cylinder having a diameter of 4 cm, and 1 drop (about 0.04 mL) of water was dropped from a height of 1 cm above the fiber piece, and the water droplets reached the fiber sheet until the mirror surface became anhydrous. The time (seconds) required for the reflection was measured. Further, when water droplets are dropped, the water absorption test value cannot be obtained when one or all of the water is transmitted from the side opposite to the side to which the water is dropped. The measurement environment was set to 25 ° C and 40 ± 5% RH. The results are shown in Table 1.

[Test Example 2: Measurement of thickness of fiber sheet]

The thickness of the fiber sheet was measured using a constant pressure thickness measuring instrument (manufactured by PG-11 J-type Teclock Corporation (measuring force: 3.7 g/cm ² , probe diameter: 10 cm ² )). The results are shown in Table 1.

Hereinafter, the types and constituent ratios of the raw materials of the fibers constituting each of the fiber sheets will be described.

Reference Examples 1 to 13: Fiber Sheets

Reference Example 1: 嫘萦 (basis weight 18 g/m ² , thickness 0.06 mm)

Reference Example 2: 嫘萦 (basis weight 20 g/m ² , thickness 0.07 mm)

Reference Example 3: Polyvinyl alcohol (PVA) + 嫘萦 + pulp + (polypropylene (PP) (core) / polyethylene (PE) (sheath)) = 3 + 37 + 32 + 28 (% by mass) ( Base weight 17g/m ² , thickness 0.07mm)

Reference Example 4: PVA + 嫘萦 + (PP (core) / PE (sheath)) = 10 + 50 + 40 (% by mass) (basis weight 21 g / m ² , thickness 0.14 mm)

Reference Example 5: Cellulose (base weight 13.5 g/m ² , thickness 0.07 mm)

Reference Example 6: (polyethylene terephthalate (PET (core)) / low melting point PET (sheath)) + pulp = 90 + 10 (% by mass) (basis weight 20 g / m ² , thickness 0.28 mm )

Reference Example 7: (PET (core) / low melting point PET (sheath section)) = 80 + 20 + Pulp (% by mass) (basis weight of 20g / m ^2, a thickness of 0.24mm)

Reference Example 8: (PET (core) / low melting point PET (sheath)) + pulp = 80 + 20 (% by mass) (basis weight 40 g / m ² , thickness 0.68 mm)

Reference Example 9: (PET (core) / low melting point PET (sheath)) + pulp = 80 + 20 (% by mass) (basis weight: 50 g/m ² , thickness: 0.85 mm)

Reference Example 10: 嫘萦+polyolefin=80+20 (basis weight 80 g/m ² , thickness 0.65 mm)

Reference Example 11: Pulp (basis weight 40 g/m ² , thickness 0.7 mm)

Reference Example 12: Polyolefin (basis weight 50 g/m ² , thickness 0.55 mm)

Reference Example 13: PET (core) / PE (sheath) (basis weight 18 g / m ² , thickness 0.37 mm)

According to the results of Table 1, the water absorption test values of the fiber sheets of Reference Examples 1 to 9 showed values of 1 to 16,000 seconds, and had water absorption characteristics within a certain range. On the other hand, as the fiber sheet (refer to Examples 10 and 11) which has been conventionally used in the cooling adhesive tape, the water absorption of the fiber sheet of the hydrophobic fiber is relatively fast, and the fiber sheet having a basis weight of about 50 g/m ² is used (Reference example). 12) The water absorption is very slow, and the fiber sheet containing the fibrous sheet of the hydrophobic fiber and having a basis weight of 18 g/m ² (Reference Example 13) passes through the fiber sheet at the moment of dropping the water droplet, so that the water absorption test cannot be obtained. value.

[Examples 1 to 9 and Comparative Examples 1 to 5]

An aqueous polymer gel was prepared according to the formulation of the aqueous polymer gel shown in Table 2. Then, the fibrous sheets of Reference Examples 1 to 13 were laminated with an aqueous polymer gel in an amount shown in Table 2, and after heating and aging, a cooling patch was obtained.

Specifically, first, glycerin, a mixture of propylene glycol, carboxymethylcellulose sodium, and a dry aluminum hydroxide gel in which methyl hydroxybenzoate is dissolved is added to a kneading machine, followed by the addition of succinic acid. An aqueous solution was prepared to prepare a non-crosslinked gel stock solution. Then, the obtained uncrosslinked gel stock solution was applied to a polypropylene film and kneaded, and the amount of the aqueous polymer gel was 750 g/m ² (water content 656 g) by the Becker applicator. /m ² ) Adjust the thickness to make a sheet. After the obtained sheet was sealed to an aluminum pillow type and sealed, it was aged at 50 ° C for 5 days to carry out a crosslinking reaction in the gel stock solution to form an aqueous polymer gel. Further, the prepared gel stock solution had a pH of 4.7. The obtained aqueous polymer gel was die-cut into a square shape (area: 25 cm ² ), and the polypropylene film of one side was peeled off, and then each of the fiber sheets (5 × 5 cm) was pressed against the aqueous polymer gel to be laminated to obtain cooling. Use the patch. The pH of the aqueous polymer gel of the obtained cooling patch was 5.1.

Then, using each of the obtained cooling patches, the cooling effect was measured in accordance with the method of Test Example 3 below. The results are shown in Table 2.

[Test Example 3: Measurement of cooling effect]

Each of the cooling patches was attached to a hot plate set at 36 ° C, and the temperature of the hot plate of the attached portion was measured using a thermistor probe. The measurement was carried out in a thermo-hygrostat at 28 ° C and 60% RH. For the cooling performance, the temperature before the attachment of the sheet and the temperature at which the wafer was attached for 10 minutes and 30 minutes were measured, and the panel temperature change ⊿T ₁ (°C) was calculated by the following formula, and the cooling was performed. The effect is evaluated.

Plate temperature change ⊿T ₁ (°C)=(plate temperature after 10 minutes or 30 minutes from sheet attachment)-(plate temperature before sheet attachment)

According to the results of Table 2, in Examples 1 to 9 using the fiber sheets of Reference Examples 1 to 9, the sheet temperature was changed as compared with Comparative Example 1 having a single layer structure of only the water-containing polymer gel, and the layer of the fiber layer was laminated. Thereby improving the cooling effect. On the other hand, in Comparative Examples 2 to 5 using the fiber sheets of Reference Examples 10 to 13, the cooling effect was equal or inferior to that of Comparative Example 1.

[Examples 10 and 11, Comparative Examples 6, 7]

Using the aqueous polymer gel formed according to the formulation shown in Table 2, in Example 10, the amount of the aqueous polymer gel was adjusted to 1500 g/m ² (water content: 1315 g/m ² ) in terms of the original liquid. In the same manner as in Example 3, a cooling patch was prepared in the same manner as in Example 3 except that the water content of the aqueous polymer gel was changed to 79.4% by mass. In addition, in the same manner as in Example 7, except that the water content of the aqueous polymer gel was 63% by mass, a cooling patch was prepared. In Comparative Example 7, the water content of the aqueous polymer gel was 63% by mass, and the amount of the aqueous polymer gel was 1050 g/m ² (water content: 661 g/m ² ) in terms of the original liquid. A cooling patch was prepared in the same manner as in Example 7 except that the thickness was applied and adjusted.

Then, using each of the obtained cooling patches, the cooling effect was measured in accordance with the method of Test Example 3 described above. The results are shown in Table 2.

As a result of the results of Table 2, it was found that the temperature of the Example 10 based on the fiber sheet of Reference Example 3 and the moisture content of the chip for cooling was 1315 g/m ² was large, and the cooling effect was good. Further, in Example 11 in which the fiber sheet of Reference Example 3 and sodium carboxymethylcellulose, sodium polyacrylate, and polyacrylic acid were blended as a polymer gelling agent, the temperature of the sheet was largely changed, and the cooling effect was good. On the other hand, in Comparative Example 6 in which the moisture content in the cooling patch was 472 g/m ² , the cooling effect was good after 10 minutes of sticking, but after 30 minutes, the cooling effect was remarkably lowered, and the sustainability of the cooling effect could not be obtained. . Further, it is understood that the moisture content in the cooling patch is 585 g/m ² or more, but in Comparative Example 7 in which the water content in the aqueous polymer gel is as low as 63% by mass, the cooling effect is after 10 and 30 minutes. Weak.

[Examples 12 and 13, Comparative Example 8]

Using the aqueous polymer gel formed according to the formulation shown in Table 2, the moisture content of the aqueous polymer gel was set to 70% by mass in Example 12, and in Example 13, the aqueous polymer gel was used. The moisture content was 92% by mass, and the thickness of the aqueous polymer gel sheet was 1312 g/m ² in terms of a stock solution, and the thickness was adjusted. In Comparative Example 8, the moisture content of the aqueous polymer gel was measured. A cooling patch was prepared in the same manner as in Example 7 except that the thickness of the aqueous polymer gel sheet was adjusted to 2312 g/m ² in an amount of 79.2% by mass.

Then, using each of the obtained cooling patches, the cooling effect was measured in accordance with the method of Test Example 3 described above. The results are shown in Table 2.

According to Table 2, in Examples 12 and 13 in which the water content of the aqueous polymer gel was 70% by mass and 92% by mass, the sheet temperature was largely changed, and the cooling effect was good. On the other hand, in Comparative Example 8 in which the water content of the aqueous polymer gel was appropriately 79.2% by mass, but the moisture content in the cooling patch was too high, it was 1831 g/m ² , and the cooling effect was inferior.

[Test Example 4: Determination of skin cooling effect of humans]

The cooling effect of the human skin was measured using each of the cooling patches obtained in Examples 1, 3, 5, and 7, and Comparative Examples 5 and 8, and a commercially available cooling adhesive. Specifically, the subject is placed in a healthy male in his 30s, and the thermistor probe is attached to the forehead in advance in a measurement environment of a temperature of 29 ° C and a humidity of 60% RH, and the frontal skin is attached to the sheet. The surface temperature was measured. Thereafter, the cooling patches of Examples 1, 3, 5, and 7, and Comparative Examples 5, 8 and 9 were attached to the skin from above the thermistor probe, and the skin was attached to the skin at a specific time. The surface temperature was measured, and the skin temperature change ⊿T ₂ (°C) was calculated by the following formula. Further, as a comparative example, a commercially available cooling adhesive (a gel layer: a thickness of about 3 mm, a fibrous layer basis weight of about 96 g/m ² , a non-woven layer thickness of about 1 mm, and a water-containing polymer gel moisture content of 82.6 mass %) were used. The cooling sensitizer was not formulated) as Comparative Example 9. The results are shown in Fig. 1.

Skin temperature change ⊿T ₂ (°C)=(skin temperature after patch attachment)-(skin temperature before patch attachment)

According to the results of FIG. 1, the cooling patches of Examples 1, 3, 5 and 7 are such that the skin temperature is lowered immediately after the sheet is attached, and thereafter, the skin temperature is continuously lowered or not increased, after 15 minutes of attachment, A decrease in skin temperature of about 2 ° C in Example 1, 1.8 ° C in Example 3, 1.8 ° C in Example 5, and 1.7 ° C in Example 7 can be seen. On the other hand, it was confirmed that in Comparative Example 5, the decrease in skin temperature immediately after attachment was stopped at 1.5 ° C, and thereafter the skin temperature was not lowered, and only a decrease in skin temperature of 1.4 ° C was observed after 15 minutes of attachment, and cooling was performed. The effect is weak. Further, in Comparative Example 8, it was found that the skin temperature immediately after attachment was lowered by 1.8 ° C, but after that, the skin temperature was increased, and after 15 minutes of attachment, the skin temperature was lowered to 1.3 ° C, and the cooling effect was weak. Further, it was confirmed that the temperature of the commercially available cooling gel of Comparative Example 9 was about 2.6 ° C after the attachment, but the skin temperature increased sharply thereafter, and the skin temperature decreased to about 1.1 ° C after 15 minutes of attachment. The cooling effect is obviously weaker. As is clear from these results, in the case of the cooling patch of the present invention, the skin temperature does not rise by 0.2 ° C or more during the skin attachment, and the cooling effect continues, and a high cooling effect is obtained, and the cooling feeling continues.

[Examples 14, 15]

A cooling patch was prepared in the same manner as in Example 3, using the aqueous polymer gel formed according to the formulation shown in Table 2. Further, the lactate lactate (Symrise: Frescolat ML) formulated in Example 14, or the l-menthol system formulated in Example 15 was dissolved in polyethylene glycol (PEG400) after heating to 50 ° C, and mixed. Prepared in an aqueous polymer gel stock solution. The pH of the aqueous polymer gel of the obtained cooling patch was 5.3.

[Test Example 5: Functional evaluation test]

The functional evaluation test was carried out using each of the cooling patches obtained in Examples 3, 14, and 15 and the commercially available cooling adhesive of Comparative Example 9. Specifically, in the measurement environment of a temperature of 29 ° C and a humidity of 60% RH, each cooling patch was attached to the forehead for 60 minutes, and five professional inspectors evaluated the cold feeling based on the following criteria, and took it. The average value is set as the cool feeling score. The results are shown in Table 3.

5: I feel a sense of excitement

4: I feel a strong sense of coldness

3: I feel a cold feeling

2: Feeling a weaker cold feeling

1: I feel a little cold

0: No feeling

According to the results of Table 3, Example 3 was attached and the apparent cooling feeling continued until 30 minutes later. In contrast, in Comparative Example 9, the skin temperature gradually increased during the attachment, so even if the skin temperature was actually lower than the value before the attachment, the skin felt warm. Based on these results, it was found that the continuous cooling effect shown in FIG. 1 has a very large relationship between the strength and the sustainability of the cooling feeling, and it is understood that the cooling patch of the present invention is excellent in cooling by the skin temperature which is cooled by the attachment after cooling. Maintain the effect while the coolness continues.

Further, in Example 3, Example 14 and Example 15 in which menthyl lactate or l-menthol as a cooling agent were formulated were the same as Example 3, and the cooling feeling after 30 minutes was excellent and continued. Excellent coldness is obtained for more than 1 hour, and the sustained effect is high.

Claims (13)

A cooling patch obtained by laminating a water-containing polymer gel (A) and a fiber sheet (B): (A) a water-containing polymer gel having a water content of 65 mass% or more and 95 mass% or less. And (B) a fiber sheet having a thickness of 0.001 mm or more and 1 mm or less, a basis weight of 3 g/m ² or more and 70 g/m ² or less, and a water absorption test value of 1 to 16,000 seconds, and the moisture content of the patch is 585 g/m ² or more and 1700 g/m ² or less. The cooling patch of claim 1, wherein the fiber sheet (B) has a water absorption test value of 1/3 of a value multiplied by a fiber density of 0.25 × 10 ⁶ to 2.2 × 10 ⁶ seconds ^1/3 ‧ g /m ³ . The cooling patch according to claim 1 or 2, wherein a mass ratio of moisture to fiber (water mass/fiber mass in the cooling patch) of the cooling patch is 9 or more and 320 or less. The cooling patch according to claim 1 or 2, wherein the amount of the aqueous polymer gel (A) is 615 g/m ² or more and 2600 g/m ² or less. A cooling patch according to claim 1 or 2, wherein the fiber sheet (B) is a non-woven sheet. A cooling patch according to claim 1 or 2, wherein the fiber sheet (B) is a water-absorbent fiber. The cooling sheet according to claim 6, wherein the water absorbent fiber is one or more selected from the group consisting of ruthenium, cellulose, pulp, and polyvinyl alcohol. The cooling sheet according to claim 6, wherein the content of the water absorbent fibers in the fiber sheet (B) is 1% by mass or more and 100% by mass or less. A cooling patch according to claim 1 or 2, wherein the aqueous polymer gel (A) contains a cooling agent. The cooling patch of claim 9, wherein the cooling agent in the aqueous polymer gel (A) The content is 0.0001% by mass or more and 10% by mass or less. The cooling patch according to claim 9, wherein the cooling agent is selected from the group consisting of l-menthol, menthyl lactate, l-menthyl glyceryl ether, menthyl carbonyl glycinate, menthyl ethyl oxalate, and different One or more of menthol and camphor. The cooling patch according to claim 1 or 2, wherein the surface of the aqueous polymer gel (A) opposite to the side contacting the fiber sheet (B) is attached to the skin to cool the skin. A cooling method using the cooling patch according to claim 1 or 2, wherein the temperature of the patch attachment portion is continuously lowered at least 15 minutes after the attachment of the patch.