TW201340969A - 有效hcv抑制劑之穩定醫藥調配物 - Google Patents

有效hcv抑制劑之穩定醫藥調配物 Download PDF

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Publication number
TW201340969A
TW201340969A TW102101220A TW102101220A TW201340969A TW 201340969 A TW201340969 A TW 201340969A TW 102101220 A TW102101220 A TW 102101220A TW 102101220 A TW102101220 A TW 102101220A TW 201340969 A TW201340969 A TW 201340969A
Authority
TW
Taiwan
Prior art keywords
composition
compound
liquid pharmaceutical
less
pharmaceutical composition
Prior art date
Application number
TW102101220A
Other languages
English (en)
Chinese (zh)
Inventor
Mathias Braun
Carl Alan Busacca
Feng-Jing Chen
Edwin Gump
Jenness B Majeska
Scott Pennino
Fenghe Qiu
Maria Fernanda Villagra
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47628447&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW201340969(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of TW201340969A publication Critical patent/TW201340969A/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW102101220A 2012-01-12 2013-01-11 有效hcv抑制劑之穩定醫藥調配物 TW201340969A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261586087P 2012-01-12 2012-01-12

Publications (1)

Publication Number Publication Date
TW201340969A true TW201340969A (zh) 2013-10-16

Family

ID=47628447

Family Applications (1)

Application Number Title Priority Date Filing Date
TW102101220A TW201340969A (zh) 2012-01-12 2013-01-11 有效hcv抑制劑之穩定醫藥調配物

Country Status (27)

Country Link
US (2) US20140037719A1 (member.php)
EP (1) EP2802313A1 (member.php)
JP (1) JP2015503616A (member.php)
KR (1) KR20140109433A (member.php)
CN (1) CN104244926A (member.php)
AP (1) AP2014007760A0 (member.php)
AR (1) AR089710A1 (member.php)
AU (1) AU2013208024A1 (member.php)
BR (1) BR112014017058A8 (member.php)
CA (1) CA2861041A1 (member.php)
CL (1) CL2014001783A1 (member.php)
CO (1) CO7000774A2 (member.php)
EA (1) EA201400808A1 (member.php)
EC (1) ECSP14013104A (member.php)
HK (1) HK1204982A1 (member.php)
IL (1) IL233550A0 (member.php)
IN (1) IN2014DN05759A (member.php)
MA (1) MA35865B1 (member.php)
MX (1) MX2014008205A (member.php)
NZ (1) NZ626353A (member.php)
PE (1) PE20141817A1 (member.php)
PH (1) PH12014501598A1 (member.php)
SG (1) SG11201404042VA (member.php)
TN (1) TN2014000295A1 (member.php)
TW (1) TW201340969A (member.php)
UY (1) UY34569A (member.php)
WO (1) WO2013106506A1 (member.php)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA119315C2 (uk) 2012-07-03 2019-06-10 Гіліад Фармассет Елелсі Інгібітори вірусу гепатиту с
WO2014145095A1 (en) 2013-03-15 2014-09-18 Gilead Sciences, Inc. Macrocyclic and bicyclic inhibitors of hepatitis c virus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5329976A (en) * 1991-12-09 1994-07-19 Habley Medical Technology Corporation Syringe-filling and medication mixing dispenser
US6323180B1 (en) 1998-08-10 2001-11-27 Boehringer Ingelheim (Canada) Ltd Hepatitis C inhibitor tri-peptides
UY28240A1 (es) * 2003-03-27 2004-11-08 Boehringer Ingelheim Pharma Fases cristalinas de un potente inhibidor de la hcv
EP1654261B1 (en) 2003-05-21 2007-11-14 Boehringer Ingelheim International GmbH Hepatitis c inhibitor compounds
US7514557B2 (en) 2004-05-25 2009-04-07 Boehringer Ingelheim International Gmbh Process for preparing acyclic HCV protease inhibitors
WO2006130552A2 (en) * 2005-06-02 2006-12-07 Schering Corporation Methods of treating hepatitis c virus
MY153093A (en) 2008-09-16 2014-12-31 Boehringer Ingelheim Int Crystalline forms of a 2-thiazolyl-4-quinolinyl-oxy derivative, a potent hcv inhibitor
UA105777C2 (uk) * 2008-11-21 2014-06-25 Бьорінгер Інгельхайм Інтернаціональ Гмбх Фармацевтична композиція ефективного інгібітора вгс для перорального введення
KR101685941B1 (ko) 2009-07-07 2016-12-13 베링거 인겔하임 인터내셔날 게엠베하 C형 간염 바이러스 프로테아제 억제제를 위한 약제학적 조성물

Also Published As

Publication number Publication date
PH12014501598A1 (en) 2014-10-08
BR112014017058A2 (pt) 2017-06-13
BR112014017058A8 (pt) 2017-07-04
CN104244926A (zh) 2014-12-24
US20140037719A1 (en) 2014-02-06
JP2015503616A (ja) 2015-02-02
AU2013208024A1 (en) 2014-07-10
US20150190458A1 (en) 2015-07-09
CO7000774A2 (es) 2014-07-21
EP2802313A1 (en) 2014-11-19
AP2014007760A0 (en) 2014-07-31
IN2014DN05759A (member.php) 2015-04-10
UY34569A (es) 2013-07-31
AR089710A1 (es) 2014-09-10
KR20140109433A (ko) 2014-09-15
CA2861041A1 (en) 2013-07-18
SG11201404042VA (en) 2014-08-28
MX2014008205A (es) 2014-08-08
NZ626353A (en) 2016-02-26
CL2014001783A1 (es) 2014-12-12
EA201400808A1 (ru) 2015-02-27
PE20141817A1 (es) 2014-12-17
HK1204982A1 (en) 2015-12-11
ECSP14013104A (es) 2015-11-30
MA35865B1 (fr) 2014-12-01
TN2014000295A1 (en) 2015-12-21
IL233550A0 (en) 2014-08-31
WO2013106506A1 (en) 2013-07-18

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