TW201004641A - Treatment of inflammatory diseases with mammal beta defensins - Google Patents

Treatment of inflammatory diseases with mammal beta defensins Download PDF

Info

Publication number
TW201004641A
TW201004641A TW098124404A TW98124404A TW201004641A TW 201004641 A TW201004641 A TW 201004641A TW 098124404 A TW098124404 A TW 098124404A TW 98124404 A TW98124404 A TW 98124404A TW 201004641 A TW201004641 A TW 201004641A
Authority
TW
Taiwan
Prior art keywords
defensin
hbd2
human
tnf
mammalian
Prior art date
Application number
TW098124404A
Other languages
English (en)
Chinese (zh)
Inventor
Tanja Maria Rosenkilde Kjaer
Thomas Kruse
Per Holse Mygind
Karoline Sidelmann Brinch
Soeren Kjaerulff
Birgitte Andersen
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41445843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW201004641(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novozymes As filed Critical Novozymes As
Publication of TW201004641A publication Critical patent/TW201004641A/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1729Cationic antimicrobial peptides, e.g. defensins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
TW098124404A 2008-07-18 2009-07-20 Treatment of inflammatory diseases with mammal beta defensins TW201004641A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP08160761 2008-07-18
EP08162486 2008-08-15
EP08163614 2008-09-03
EP09160448 2009-05-15

Publications (1)

Publication Number Publication Date
TW201004641A true TW201004641A (en) 2010-02-01

Family

ID=41445843

Family Applications (1)

Application Number Title Priority Date Filing Date
TW098124404A TW201004641A (en) 2008-07-18 2009-07-20 Treatment of inflammatory diseases with mammal beta defensins

Country Status (18)

Country Link
US (1) US20100016232A1 (xx)
EP (1) EP2320929B1 (xx)
JP (1) JP2011528332A (xx)
KR (2) KR20110031962A (xx)
CN (1) CN102159232A (xx)
AP (1) AP2011005537A0 (xx)
AR (1) AR072524A1 (xx)
AU (1) AU2009272680A1 (xx)
BR (1) BRPI0915780A2 (xx)
CA (1) CA2730674A1 (xx)
CL (1) CL2011000098A1 (xx)
EA (1) EA201170218A1 (xx)
IL (1) IL210714A0 (xx)
MX (1) MX2011000569A (xx)
NZ (1) NZ590466A (xx)
TW (1) TW201004641A (xx)
WO (1) WO2010007165A2 (xx)
ZA (1) ZA201100462B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR072525A1 (es) * 2008-07-18 2010-09-01 Novozymes As Tratamiento de artritis reumatoidea con beta defensinas de mamiferos. uso. metodo.
NZ593653A (en) 2008-07-18 2012-09-28 Novozymes Adenium Biotech As Treatment of inflammatory bowel diseases with mammal beta defensins
AU2011239466B2 (en) 2010-04-15 2015-01-22 Marine Polymer Technologies, Inc. Anti-bacterial applications of poly -N-acetylglucosamine nanofibers
KR101320472B1 (ko) * 2010-06-16 2013-10-23 주식회사 나이벡 항균 또는 항염증 활성을 가지는 펩타이드 및 이를 유효성분으로 함유하는 약제학적 조성물
NZ732118A (en) 2011-04-15 2018-11-30 Marine Polymer Tech Inc Treatment of disease with poly-n-acetylglucosamine nanofibers
JP6219277B2 (ja) 2011-07-08 2017-10-25 ディフェンシン セラピューティクス アンパルトセルスカブDefensin Therapeutics Aps 炎症性腸疾患の経口治療
US20130052213A1 (en) 2011-08-19 2013-02-28 Novozymes A/S Novel immunomodulatory peptide
JP6151981B2 (ja) * 2013-06-18 2017-06-21 一般社団法人健康科学リソースセンター 関節リウマチ患者における生物学的製剤の有効性の予測方法
WO2016029043A1 (en) 2014-08-21 2016-02-25 The General Hospital Corporation Tumor necrosis factor superfamily and tnf-like ligand muteins and methods of preparing and using the same
GB201603653D0 (en) * 2016-03-02 2016-04-13 Cambridge Entpr Ltd Combination Therapy
MX2019006848A (es) 2016-12-13 2019-10-07 Defensin Therapeutics Aps Metodos para tratar condiciones inflamatorias de los pulmones.
KR102631542B1 (ko) 2018-03-14 2024-02-01 서울대학교산학협력단 염증 감소능 및 줄기세포로부터 연골세포로의 분화 촉진능을 가지는 이중 기능성 펩타이드 및 이의 용도
KR102631543B1 (ko) 2018-03-14 2024-02-01 서울대학교산학협력단 세포 투과능 및 근육 재생능을 가지는 이중 기능성 펩타이드 및 이의 용도
WO2020046002A1 (ko) * 2018-08-31 2020-03-05 주식회사 나이벡 다중의 질환 바이오마커의 기능 및 발현을 억제하는 펩타이드의 신규한 용도
WO2023144701A1 (en) 2022-01-28 2023-08-03 Johnson & Johnson Consumer Inc. Biomarkers predictive of atopic dermatitis
WO2023194839A1 (en) 2022-04-04 2023-10-12 Donnelly Window of opportunity skin treatment regimen and composition for preventing the onset of or treating atopic dermatitis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7338936B2 (en) * 2000-11-28 2008-03-04 House Ear Institute Use of antimicrobial proteins and peptides for the treatment of otitis media and paranasal sinusitis
US20080194481A1 (en) * 2001-12-21 2008-08-14 Human Genome Sciences, Inc. Albumin Fusion Proteins
KR20050089827A (ko) * 2002-12-19 2005-09-08 이츠차크 힐만 항균성 펩티드 억제물을 통한 질환 치료
GB0514482D0 (en) * 2005-07-14 2005-08-17 Ares Trading Sa Protein
WO2007081486A2 (en) * 2005-12-15 2007-07-19 Ventria Bioscience Oral administration of defensins to treat intestinal diseases
WO2009043507A2 (en) * 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
AR072525A1 (es) * 2008-07-18 2010-09-01 Novozymes As Tratamiento de artritis reumatoidea con beta defensinas de mamiferos. uso. metodo.
NZ593653A (en) * 2008-07-18 2012-09-28 Novozymes Adenium Biotech As Treatment of inflammatory bowel diseases with mammal beta defensins

Also Published As

Publication number Publication date
BRPI0915780A2 (pt) 2019-03-12
EA201170218A1 (ru) 2011-08-30
US20100016232A1 (en) 2010-01-21
CA2730674A1 (en) 2010-01-21
EP2320929A2 (en) 2011-05-18
AU2009272680A1 (en) 2010-01-21
JP2011528332A (ja) 2011-11-17
WO2010007165A3 (en) 2010-06-03
CL2011000098A1 (es) 2011-10-07
MX2011000569A (es) 2011-02-23
CN102159232A (zh) 2011-08-17
NZ590466A (en) 2012-08-31
KR20110044863A (ko) 2011-05-02
ZA201100462B (en) 2013-03-27
WO2010007165A2 (en) 2010-01-21
EP2320929B1 (en) 2019-05-29
IL210714A0 (en) 2011-03-31
AR072524A1 (es) 2010-09-01
AP2011005537A0 (en) 2011-02-28
KR20110031962A (ko) 2011-03-29

Similar Documents

Publication Publication Date Title
TW201004641A (en) Treatment of inflammatory diseases with mammal beta defensins
Zaiou et al. Cathelicidins, essential gene-encoded mammalian antibiotics
TW201138810A (en) Treatment of inflammatory bowel diseases with mammal beta defensins
JP2014523906A (ja) 炎症性腸疾患の経口治療
TW201004639A (en) Treatment of rheumatoid arthritis with mammal beta defensins
Afacan et al. Host defense peptides: immune modulation and antimicrobial activity in vivo
US20090253629A1 (en) Use of defensins against meningitis
Class et al. Patent application title: Treatment Of Rheumatoid Arthritis With Mammal Beta Defensins Inventors: Tanja Maria Rosenkilde Kjaer (Holte, DK) Tanja Maria Rosenkilde Kjaer (Holte, DK) Thomas Kruse (Copenhagen N, DK) Per Holse Mygind (Vaerloese, DK) Per Holse Mygind (Vaerloese, DK) Karoline Sidelmann Brinch (Copenhagen Nv, DK) Karoline Sidelmann Brinch (Copenhagen Nv, DK) Soeren Kjaerulff (Holte, DK) Birgitte Andersen (Bagsvaerd, DK) Birgitte Andersen (Bagsvaerd, DK) Assignees: Novozymes A/S
Patil Genome-wide identification of mammalian defensins and functional analysis of a novel defensin-related peptide
AU2011203033A1 (en) Treatment of inflammatory bowel diseases with mammal beta defensins