TW200831485A - New pyridazine derivatives with MCH antagonistic activity and medicaments comprising these compounds - Google Patents

New pyridazine derivatives with MCH antagonistic activity and medicaments comprising these compounds Download PDF

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Publication number
TW200831485A
TW200831485A TW096147077A TW96147077A TW200831485A TW 200831485 A TW200831485 A TW 200831485A TW 096147077 A TW096147077 A TW 096147077A TW 96147077 A TW96147077 A TW 96147077A TW 200831485 A TW200831485 A TW 200831485A
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Taiwan
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group
alkyl
doc
cycloalkyl
amino
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TW096147077A
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English (en)
Chinese (zh)
Inventor
Thorsten Lehmann-Lintz
Dirk Stenkamp
Gerald Juergen Roth
Stephan Georg Mueller
Joerg Kley
Armin Heckel
Klaus Rudolf
Marcus Schindler
Ralf Lotz
Patrick Tielmann
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Boehringer Ingelheim Int
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Publication of TW200831485A publication Critical patent/TW200831485A/zh

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    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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TW096147077A 2006-12-11 2007-12-10 New pyridazine derivatives with MCH antagonistic activity and medicaments comprising these compounds TW200831485A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06125763 2006-12-11

Publications (1)

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TW200831485A true TW200831485A (en) 2008-08-01

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TW096147077A TW200831485A (en) 2006-12-11 2007-12-10 New pyridazine derivatives with MCH antagonistic activity and medicaments comprising these compounds

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Country Link
US (1) US20100197908A1 (enExample)
EP (1) EP2102171A1 (enExample)
JP (1) JP2010512366A (enExample)
AR (1) AR064293A1 (enExample)
CA (1) CA2671984A1 (enExample)
CL (1) CL2007003580A1 (enExample)
TW (1) TW200831485A (enExample)
WO (1) WO2008071646A1 (enExample)

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AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
AR081626A1 (es) * 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
EP2650284A1 (en) * 2012-04-10 2013-10-16 Merz Pharma GmbH & Co. KGaA Heterocyclic derivatives as metabotropic glutamate receptor modulators
CN104971286A (zh) * 2015-05-25 2015-10-14 广东工业大学 一种治疗肩腰腿不适症的中药组合物
BR112018077281A2 (pt) * 2016-07-01 2019-04-02 Boulos & Cooper Pharmaceuticals Pty Ltd novos antibióticos
PE20190414A1 (es) 2016-08-05 2019-03-19 Boehringer Ingelheim Int Derivados de oxadiazolopiridina para el uso como inhibidores de ghrelin o-aciltransferasa (goat)
MY206745A (en) 2018-10-29 2025-01-04 Boehringer Ingelheim Int Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof
JP7425793B2 (ja) 2018-10-29 2024-01-31 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ピリジニルスルホンアミド誘導体、医薬組成物およびそれらの使用
US11465982B2 (en) 2019-07-22 2022-10-11 Boehringer Ingelheim International Gmbh Pyridazines
US11485727B2 (en) * 2019-07-22 2022-11-01 Boehringer Ingelheim International Gmbh N-methyl, n-(6-(methoxy)pyridazin-3-yl) amine derivatives as autotaxin (ATX) modulators
JP7240554B2 (ja) * 2019-07-22 2023-03-15 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 炎症性気道疾患又は線維性疾患の治療のためのオートタキシン（ａｔｘ）モジュレーターとしてのｎ－メチル，１－（６－（メトキシ）ピリダジン－３－イル）アミン誘導体
JP7720846B2 (ja) * 2020-07-08 2025-08-08 第一三共株式会社 １，３－ベンゾジオキソール誘導体の製造方法

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DE102004017933A1 (de) 2004-04-14 2005-11-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
DE102004017934A1 (de) 2004-04-14 2005-11-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
DE102004017935A1 (de) 2004-04-14 2005-11-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
DE102004017932A1 (de) * 2004-04-14 2005-11-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
CA2622944A1 (en) * 2005-09-30 2007-04-12 F. Hoffmann-La Roche Ag Diazine azole derivatives, their manufacture and use as pharmaceutical agents
US20110039860A1 (en) * 2008-05-07 2011-02-17 Cangming Yang Soluble epoxide hydrolase inhibitors, compositions containing such compounds and methods of treatment

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CL2007003580A1 (es) 2009-03-27
EP2102171A1 (en) 2009-09-23
CA2671984A1 (en) 2008-06-19

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