TW200745101A - 9-Azabicyclo[3.3.1]nonane derivatives - Google Patents

9-Azabicyclo[3.3.1]nonane derivatives

Info

Publication number
TW200745101A
TW200745101A TW095135223A TW95135223A TW200745101A TW 200745101 A TW200745101 A TW 200745101A TW 095135223 A TW095135223 A TW 095135223A TW 95135223 A TW95135223 A TW 95135223A TW 200745101 A TW200745101 A TW 200745101A
Authority
TW
Taiwan
Prior art keywords
azabicyclo
5alkyl
nonane
phenoxy
methyl
Prior art date
Application number
TW095135223A
Other languages
English (en)
Inventor
Matilda Jane Bingham
Margaret Jean Huggett
Mark Huggett
Yasuko Kiyoi
Susan Elizabeth Napier
Olaf Nimz
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35482843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200745101(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Organon Nv filed Critical Organon Nv
Publication of TW200745101A publication Critical patent/TW200745101A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW095135223A 2005-09-30 2006-09-22 9-Azabicyclo[3.3.1]nonane derivatives TW200745101A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05109123 2005-09-30

Publications (1)

Publication Number Publication Date
TW200745101A true TW200745101A (en) 2007-12-16

Family

ID=35482843

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095135223A TW200745101A (en) 2005-09-30 2006-09-22 9-Azabicyclo[3.3.1]nonane derivatives

Country Status (8)

Country Link
EP (1) EP1934212B1 (zh)
JP (1) JP2009510026A (zh)
CN (1) CN101291931A (zh)
AR (1) AR057835A1 (zh)
CA (1) CA2623359A1 (zh)
PE (1) PE20070491A1 (zh)
TW (1) TW200745101A (zh)
WO (1) WO2007039563A1 (zh)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006008945D1 (de) 2005-06-28 2009-10-15 Sanofi Aventis Isochinolinderivate als inhibitoren von rho-kinase
NI200800025A (es) 2005-07-26 2009-03-03 Derivados de isoquinolona sustituidos con piperidinilo en calidad de inhibidores de rho-quinasa
NZ565669A (en) 2005-07-26 2010-05-28 Sanofi Aventis Cyclohexylamin isoquinolone derivatives as Rho-kinase inhibitors
PL2102164T3 (pl) 2006-12-27 2011-05-31 Sanofi Aventis Pochodne izochinoliny i izochinolinonu podstawione cykloalkiloaminami
WO2008077552A1 (en) 2006-12-27 2008-07-03 Sanofi-Aventis Substituted isoquinoline and isoquinolinone derivatives
DK2132194T3 (da) 2006-12-27 2011-06-27 Sanofi Aventis Substituerede isoquinoliner og deres anvendelse som Rho-kinase inhibitorer
WO2008077550A1 (en) 2006-12-27 2008-07-03 Sanofi-Aventis Substituted isoquinoline and isoquinolinone derivatives as inhibitors of rho-kinase
CA2673917C (en) 2006-12-27 2015-01-27 Sanofi-Aventis Cycloalkylamine substituted isoquinolone derivatives
MY151953A (en) 2006-12-27 2014-07-31 Sanofi Aventis Cycloalkylamine substituted isoquinoline derivatives
MX2010013974A (es) 2008-06-24 2011-01-14 Sanofi Aventis Isoquinolinas e isoquinolinonas 6-sustituidas.
DK2303846T3 (en) 2008-06-24 2015-08-03 Sanofi Sa SUBSTITUTED isoquinolines AND ISOQUINOLINONER AS RHO kinase inhibitors
RU2532481C2 (ru) 2008-06-24 2014-11-10 Санофи-Авентис Би- и полициклические замещенные производные изохинолина и изохинолинона, полезные в качестве ингибиторов rho-киназы
TWI471095B (zh) 2009-12-21 2015-02-01 Nippon Soda Co 環胺化合物及殺蟎劑
EP2523562B1 (en) * 2010-01-11 2019-01-02 Astraea Therapeutics, LLC Nicotinic acetylcholine receptor modulators
AR081721A1 (es) 2010-02-25 2012-10-17 Nippon Soda Co Compuesto de amina ciclica y acaricida
WO2014005274A1 (zh) * 2012-07-03 2014-01-09 海南卫康制药(潜山)有限公司 多取代的8-氮杂环【3.2.1】辛烷化合物
JP6197203B2 (ja) * 2013-09-06 2017-09-20 日本曹達株式会社 エンド−９−アザビシクロ［３．３．１］ノナン−３−オール誘導体の製造方法
TWI562914B (en) * 2014-05-30 2016-12-21 Jamesyuming Pan Airbag with multiple layers of cushioning effect
CN104341275B (zh) * 2014-10-24 2016-05-18 江苏鼎烨药业有限公司 一种2，6-二羟基甲苯的合成方法
TW201838974A (zh) 2017-04-19 2018-11-01 印度商Ｐｉ工業公司 具殺菌性質之雜環化合物
US20200281202A1 (en) 2017-09-08 2020-09-10 Pi Industries Ltd. Novel fungicidal heterocyclic compounds
WO2019048988A1 (en) 2017-09-08 2019-03-14 Pi Industries Ltd. NOVEL FUNGICIDE HETEROCYCLIC COMPOUNDS
AR120376A1 (es) 2019-11-11 2022-02-09 Pi Industries Ltd Heteroaril piperidiniletanonas sustituidas con actividad fungicida
UY38940A (es) 2019-11-11 2021-06-30 Pi Industries Ltd Nuevas piridiniloxi piperidiniletanonas sustituidas
AR120377A1 (es) 2019-11-11 2022-02-09 Pi Industries Ltd Derivados heteroaromáticos de sulfiliminas o sulfoximinas con actividad fungicida

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3087763B2 (ja) * 1990-11-30 2000-09-11 三井化学株式会社 新規な複素環式化合物およびそれを含有する医薬組成物
FR2738569B1 (fr) * 1995-09-12 1997-11-28 Pf Medicament Nouveaux derives naphtamide de 3 beta-amino azabicyclo octane ou nonane, leur procede de preparation, leur utilisation a titre de medicament antipsychotique
EP1403255A4 (en) * 2001-06-12 2005-04-06 Sumitomo Pharma INHIBITORS OF RHO KINASE
US7148236B2 (en) 2002-01-17 2006-12-12 Merck & Co., Inc. Modulators of acetylcholine receptors
AU2003287024A1 (en) 2002-11-05 2004-06-03 Eli Lilly And Company 3-aryloxy/thio-3-substituted propanamines and their use in inhibiting serotonin and norephinephrine reuptake
US7407970B2 (en) 2003-06-24 2008-08-05 Neurosearch A/S 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
JP2008502650A (ja) * 2004-06-18 2008-01-31 ノイロサーチ アクティーゼルスカブ 新規な９−アザ−ビシクロ［３．３．１］ノナン誘導体及びこれらのモノアミン神経伝達物質再取り込み阻害剤としての使用

Also Published As

Publication number Publication date
WO2007039563A1 (en) 2007-04-12
EP1934212B1 (en) 2013-02-20
JP2009510026A (ja) 2009-03-12
AR057835A1 (es) 2007-12-19
EP1934212A1 (en) 2008-06-25
PE20070491A1 (es) 2007-06-13
CA2623359A1 (en) 2007-04-12
CN101291931A (zh) 2008-10-22

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