TW200735869A - Diaryl ureas for treating pulmonary hypertension - Google Patents

Diaryl ureas for treating pulmonary hypertension

Info

Publication number
TW200735869A
TW200735869A TW095141430A TW95141430A TW200735869A TW 200735869 A TW200735869 A TW 200735869A TW 095141430 A TW095141430 A TW 095141430A TW 95141430 A TW95141430 A TW 95141430A TW 200735869 A TW200735869 A TW 200735869A
Authority
TW
Taiwan
Prior art keywords
pulmonary hypertension
treating pulmonary
diaryl ureas
diaryl
urea compound
Prior art date
Application number
TW095141430A
Other languages
English (en)
Inventor
Peter Sandner
Hanna Tinel
Joachim Huetter
Bernd Riedl
Martina Klein
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of TW200735869A publication Critical patent/TW200735869A/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW095141430A 2005-11-10 2006-11-09 Diaryl ureas for treating pulmonary hypertension TW200735869A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05024508 2005-11-10
EP05027449 2005-12-15
EP06007775 2006-04-13

Publications (1)

Publication Number Publication Date
TW200735869A true TW200735869A (en) 2007-10-01

Family

ID=37651281

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095141430A TW200735869A (en) 2005-11-10 2006-11-09 Diaryl ureas for treating pulmonary hypertension

Country Status (23)

Country Link
US (1) US20090176791A1 (zh)
EP (1) EP1948176B1 (zh)
JP (1) JP5075832B2 (zh)
KR (1) KR20080066030A (zh)
AR (1) AR057848A1 (zh)
AT (1) ATE493986T1 (zh)
AU (1) AU2006312713A1 (zh)
BR (1) BRPI0618524A2 (zh)
CA (1) CA2628847A1 (zh)
CU (1) CU23815A3 (zh)
DE (1) DE602006019468D1 (zh)
DK (1) DK1948176T3 (zh)
EC (1) ECSP088429A (zh)
IL (1) IL191010A0 (zh)
MY (1) MY144860A (zh)
NO (1) NO20082497L (zh)
NZ (1) NZ568031A (zh)
PL (1) PL1948176T3 (zh)
PT (1) PT1948176E (zh)
SV (1) SV2009002899A (zh)
TW (1) TW200735869A (zh)
UY (1) UY29902A1 (zh)
WO (1) WO2007054215A1 (zh)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
JP2002534468A (ja) 1999-01-13 2002-10-15 バイエル コーポレイション ｐ３８キナーゼ阻害剤としてのω−カルボキシアリール置換ジフェニル尿素
WO2003068228A1 (en) 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Aryl ureas with angiogenesis inhibiting activity
US7557129B2 (en) 2003-02-28 2009-07-07 Bayer Healthcare Llc Cyanopyridine derivatives useful in the treatment of cancer and other disorders
PT1636585E (pt) 2003-05-20 2008-03-27 Bayer Pharmaceuticals Corp Diarilureias com actividade inibidora de cinase
US8637553B2 (en) 2003-07-23 2014-01-28 Bayer Healthcare Llc Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
JP5304241B2 (ja) 2005-03-07 2013-10-02 バイエル・ヘルスケア・エルエルシー 癌の処置用のオメガ−カルボキシアリール置換ジフェニルウレアを含む医薬組成物
WO2007087575A2 (en) * 2006-01-24 2007-08-02 University Of Chicago Compositions and methods for treating pulmonary hypertension
AR062927A1 (es) * 2006-10-11 2008-12-17 Bayer Healthcare Ag 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
JP5885012B2 (ja) 2007-01-19 2016-03-15 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ Ｋｉｔ阻害剤に対して獲得した抵抗性を有する癌の処置
US20110178137A1 (en) * 2008-06-25 2011-07-21 Bayer Schering Pharma Aktiengesellschaft Diaryl urea for treating heart failure
SG189038A1 (en) 2010-10-01 2013-05-31 Bayer Ip Gmbh Substituted n-(2-arylamino)aryl sulfonamide-containing combinations
US8710043B2 (en) 2011-06-24 2014-04-29 Amgen Inc. TRPM8 antagonists and their use in treatments
CA2839703A1 (en) 2011-06-24 2012-12-27 Amgen Inc. Trpm8 antagonists and their use in treatments
US8586527B2 (en) * 2011-10-20 2013-11-19 Jaipal Singh Cerivastatin to treat pulmonary disorders
US8952009B2 (en) 2012-08-06 2015-02-10 Amgen Inc. Chroman derivatives as TRPM8 inhibitors
US9815815B2 (en) 2013-01-10 2017-11-14 Pulmokine, Inc. Non-selective kinase inhibitors
CN111743901B (zh) 2013-10-11 2023-09-12 普尔莫凯恩股份有限公司 喷雾干燥制剂
EP3082428A4 (en) 2013-12-09 2017-08-02 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto
US11057446B2 (en) 2015-05-14 2021-07-06 Bright Data Ltd. System and method for streaming content from multiple servers
AU2017348354B2 (en) 2016-10-27 2023-06-15 Pulmokine, Inc. Combination therapy for treating pulmonary hypertension

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7928239B2 (en) * 1999-01-13 2011-04-19 Bayer Healthcare Llc Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
US20020065296A1 (en) * 1999-01-13 2002-05-30 Bayer Corporation Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors
WO2003068228A1 (en) * 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Aryl ureas with angiogenesis inhibiting activity
PT1636585E (pt) * 2003-05-20 2008-03-27 Bayer Pharmaceuticals Corp Diarilureias com actividade inibidora de cinase

Also Published As

Publication number Publication date
EP1948176A1 (en) 2008-07-30
JP5075832B2 (ja) 2012-11-21
ECSP088429A (es) 2008-07-30
CU23815A3 (es) 2012-06-21
ATE493986T1 (de) 2011-01-15
PL1948176T3 (pl) 2011-05-31
DK1948176T3 (da) 2011-04-18
SV2009002899A (es) 2009-04-28
UY29902A1 (es) 2007-06-29
IL191010A0 (en) 2009-08-03
AR057848A1 (es) 2007-12-19
US20090176791A1 (en) 2009-07-09
BRPI0618524A2 (pt) 2011-09-06
JP2009514909A (ja) 2009-04-09
MY144860A (en) 2011-11-30
DE602006019468D1 (de) 2011-02-17
PT1948176E (pt) 2011-03-07
WO2007054215A1 (en) 2007-05-18
NZ568031A (en) 2011-06-30
EP1948176B1 (en) 2011-01-05
KR20080066030A (ko) 2008-07-15
CU20080082A7 (es) 2011-07-11
CA2628847A1 (en) 2007-05-18
AU2006312713A1 (en) 2007-05-18
NO20082497L (no) 2008-06-03

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