NO20082497L - Diarylureaer for behandling av pulmonal hypertensjon - Google Patents
Diarylureaer for behandling av pulmonal hypertensjonInfo
- Publication number
- NO20082497L NO20082497L NO20082497A NO20082497A NO20082497L NO 20082497 L NO20082497 L NO 20082497L NO 20082497 A NO20082497 A NO 20082497A NO 20082497 A NO20082497 A NO 20082497A NO 20082497 L NO20082497 L NO 20082497L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- pulmonary hypertension
- diarylureas
- diarylurea compound
- diarylurea
- Prior art date
Links
- 208000002815 pulmonary hypertension Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- MLDQJTXFUGDVEO-UHFFFAOYSA-N BAY-43-9006 Chemical compound C1=NC(C(=O)NC)=CC(OC=2C=CC(NC(=O)NC=3C=C(C(Cl)=CC=3)C(F)(F)F)=CC=2)=C1 MLDQJTXFUGDVEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229960003787 sorafenib Drugs 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Det er beskrevet fannasøytiske preparater for behandling, forebyggelse eller kontroll av pulmonal hypertensjon omfattende minst en diarylureaforbindelse eventuelt kombinert med minst ett ytterligere terapeutisk middel. Nyttige kombinasjoner omfatter for eksempel BAY 43-9006 som en diarylureaforbindelse.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05024508 | 2005-11-10 | ||
EP05027449 | 2005-12-15 | ||
EP06007775 | 2006-04-13 | ||
PCT/EP2006/010405 WO2007054215A1 (en) | 2005-11-10 | 2006-10-30 | Diaryl ureas for treating pulmonary hypertension |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20082497L true NO20082497L (no) | 2008-06-03 |
Family
ID=37651281
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082497A NO20082497L (no) | 2005-11-10 | 2008-06-03 | Diarylureaer for behandling av pulmonal hypertensjon |
Country Status (23)
Country | Link |
---|---|
US (1) | US20090176791A1 (no) |
EP (1) | EP1948176B1 (no) |
JP (1) | JP5075832B2 (no) |
KR (1) | KR20080066030A (no) |
AR (1) | AR057848A1 (no) |
AT (1) | ATE493986T1 (no) |
AU (1) | AU2006312713A1 (no) |
BR (1) | BRPI0618524A2 (no) |
CA (1) | CA2628847A1 (no) |
CU (1) | CU23815A3 (no) |
DE (1) | DE602006019468D1 (no) |
DK (1) | DK1948176T3 (no) |
EC (1) | ECSP088429A (no) |
IL (1) | IL191010A0 (no) |
MY (1) | MY144860A (no) |
NO (1) | NO20082497L (no) |
NZ (1) | NZ568031A (no) |
PL (1) | PL1948176T3 (no) |
PT (1) | PT1948176E (no) |
SV (1) | SV2009002899A (no) |
TW (1) | TW200735869A (no) |
UY (1) | UY29902A1 (no) |
WO (1) | WO2007054215A1 (no) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
JP2002534468A (ja) | 1999-01-13 | 2002-10-15 | バイエル コーポレイション | p38キナーゼ阻害剤としてのω−カルボキシアリール置換ジフェニル尿素 |
WO2003068228A1 (en) | 2002-02-11 | 2003-08-21 | Bayer Pharmaceuticals Corporation | Aryl ureas with angiogenesis inhibiting activity |
US7557129B2 (en) | 2003-02-28 | 2009-07-07 | Bayer Healthcare Llc | Cyanopyridine derivatives useful in the treatment of cancer and other disorders |
PT1636585E (pt) | 2003-05-20 | 2008-03-27 | Bayer Pharmaceuticals Corp | Diarilureias com actividade inibidora de cinase |
US8637553B2 (en) | 2003-07-23 | 2014-01-28 | Bayer Healthcare Llc | Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions |
JP5304241B2 (ja) | 2005-03-07 | 2013-10-02 | バイエル・ヘルスケア・エルエルシー | 癌の処置用のオメガ−カルボキシアリール置換ジフェニルウレアを含む医薬組成物 |
WO2007087575A2 (en) * | 2006-01-24 | 2007-08-02 | University Of Chicago | Compositions and methods for treating pulmonary hypertension |
AR062927A1 (es) * | 2006-10-11 | 2008-12-17 | Bayer Healthcare Ag | 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada |
JP5885012B2 (ja) | 2007-01-19 | 2016-03-15 | バイエル・ヘルスケア・エルエルシーBayer HealthCareLLC | Kit阻害剤に対して獲得した抵抗性を有する癌の処置 |
US20110178137A1 (en) * | 2008-06-25 | 2011-07-21 | Bayer Schering Pharma Aktiengesellschaft | Diaryl urea for treating heart failure |
SG189038A1 (en) | 2010-10-01 | 2013-05-31 | Bayer Ip Gmbh | Substituted n-(2-arylamino)aryl sulfonamide-containing combinations |
US8710043B2 (en) | 2011-06-24 | 2014-04-29 | Amgen Inc. | TRPM8 antagonists and their use in treatments |
CA2839703A1 (en) | 2011-06-24 | 2012-12-27 | Amgen Inc. | Trpm8 antagonists and their use in treatments |
US8586527B2 (en) * | 2011-10-20 | 2013-11-19 | Jaipal Singh | Cerivastatin to treat pulmonary disorders |
US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
US9815815B2 (en) | 2013-01-10 | 2017-11-14 | Pulmokine, Inc. | Non-selective kinase inhibitors |
CN111743901B (zh) | 2013-10-11 | 2023-09-12 | 普尔莫凯恩股份有限公司 | 喷雾干燥制剂 |
EP3082428A4 (en) | 2013-12-09 | 2017-08-02 | Respira Therapeutics, Inc. | Pde5 inhibitor powder formulations and methods relating thereto |
US11057446B2 (en) | 2015-05-14 | 2021-07-06 | Bright Data Ltd. | System and method for streaming content from multiple servers |
AU2017348354B2 (en) | 2016-10-27 | 2023-06-15 | Pulmokine, Inc. | Combination therapy for treating pulmonary hypertension |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7928239B2 (en) * | 1999-01-13 | 2011-04-19 | Bayer Healthcare Llc | Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas |
US20020065296A1 (en) * | 1999-01-13 | 2002-05-30 | Bayer Corporation | Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors |
WO2003068228A1 (en) * | 2002-02-11 | 2003-08-21 | Bayer Pharmaceuticals Corporation | Aryl ureas with angiogenesis inhibiting activity |
PT1636585E (pt) * | 2003-05-20 | 2008-03-27 | Bayer Pharmaceuticals Corp | Diarilureias com actividade inibidora de cinase |
-
2006
- 2006-10-30 PT PT06828882T patent/PT1948176E/pt unknown
- 2006-10-30 WO PCT/EP2006/010405 patent/WO2007054215A1/en active Application Filing
- 2006-10-30 PL PL06828882T patent/PL1948176T3/pl unknown
- 2006-10-30 DE DE602006019468T patent/DE602006019468D1/de active Active
- 2006-10-30 DK DK06828882.8T patent/DK1948176T3/da active
- 2006-10-30 US US12/084,659 patent/US20090176791A1/en not_active Abandoned
- 2006-10-30 MY MYPI20081362A patent/MY144860A/en unknown
- 2006-10-30 BR BRPI0618524-0A patent/BRPI0618524A2/pt not_active IP Right Cessation
- 2006-10-30 EP EP06828882A patent/EP1948176B1/en not_active Not-in-force
- 2006-10-30 AU AU2006312713A patent/AU2006312713A1/en not_active Abandoned
- 2006-10-30 AT AT06828882T patent/ATE493986T1/de active
- 2006-10-30 CA CA002628847A patent/CA2628847A1/en not_active Abandoned
- 2006-10-30 JP JP2008539298A patent/JP5075832B2/ja not_active Expired - Fee Related
- 2006-10-30 KR KR1020087011176A patent/KR20080066030A/ko not_active Application Discontinuation
- 2006-10-30 NZ NZ568031A patent/NZ568031A/en not_active IP Right Cessation
- 2006-10-31 AR ARP060104766A patent/AR057848A1/es not_active Application Discontinuation
- 2006-11-07 UY UY29902A patent/UY29902A1/es unknown
- 2006-11-09 TW TW095141430A patent/TW200735869A/zh unknown
-
2008
- 2008-04-27 IL IL191010A patent/IL191010A0/en unknown
- 2008-05-06 EC EC2008008429A patent/ECSP088429A/es unknown
- 2008-05-06 SV SV2008002899A patent/SV2009002899A/es unknown
- 2008-05-08 CU CU20080082A patent/CU23815A3/es not_active IP Right Cessation
- 2008-06-03 NO NO20082497A patent/NO20082497L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1948176A1 (en) | 2008-07-30 |
JP5075832B2 (ja) | 2012-11-21 |
ECSP088429A (es) | 2008-07-30 |
CU23815A3 (es) | 2012-06-21 |
ATE493986T1 (de) | 2011-01-15 |
PL1948176T3 (pl) | 2011-05-31 |
DK1948176T3 (da) | 2011-04-18 |
SV2009002899A (es) | 2009-04-28 |
UY29902A1 (es) | 2007-06-29 |
IL191010A0 (en) | 2009-08-03 |
AR057848A1 (es) | 2007-12-19 |
US20090176791A1 (en) | 2009-07-09 |
BRPI0618524A2 (pt) | 2011-09-06 |
JP2009514909A (ja) | 2009-04-09 |
MY144860A (en) | 2011-11-30 |
DE602006019468D1 (de) | 2011-02-17 |
PT1948176E (pt) | 2011-03-07 |
WO2007054215A1 (en) | 2007-05-18 |
NZ568031A (en) | 2011-06-30 |
EP1948176B1 (en) | 2011-01-05 |
KR20080066030A (ko) | 2008-07-15 |
TW200735869A (en) | 2007-10-01 |
CU20080082A7 (es) | 2011-07-11 |
CA2628847A1 (en) | 2007-05-18 |
AU2006312713A1 (en) | 2007-05-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |