TW200726471A - Heteroaryl derivatives for treating viruses - Google Patents
Heteroaryl derivatives for treating virusesInfo
- Publication number
- TW200726471A TW200726471A TW095122749A TW95122749A TW200726471A TW 200726471 A TW200726471 A TW 200726471A TW 095122749 A TW095122749 A TW 095122749A TW 95122749 A TW95122749 A TW 95122749A TW 200726471 A TW200726471 A TW 200726471A
- Authority
- TW
- Taiwan
- Prior art keywords
- heteroaryl derivatives
- treating viruses
- treating
- viruses
- heteroaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69370005P | 2005-06-24 | 2005-06-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200726471A true TW200726471A (en) | 2007-07-16 |
Family
ID=37499598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095122749A TW200726471A (en) | 2005-06-24 | 2006-06-23 | Heteroaryl derivatives for treating viruses |
Country Status (14)
Country | Link |
---|---|
US (1) | US20060293320A1 (zh) |
EP (1) | EP1910337A2 (zh) |
JP (1) | JP2008546802A (zh) |
KR (1) | KR20080040677A (zh) |
CN (1) | CN101223161A (zh) |
AR (1) | AR054797A1 (zh) |
AU (1) | AU2006261132A1 (zh) |
BR (1) | BRPI0612124A2 (zh) |
CA (1) | CA2613261A1 (zh) |
MA (1) | MA28394B1 (zh) |
MX (1) | MX2007016144A (zh) |
PE (1) | PE20070124A1 (zh) |
TW (1) | TW200726471A (zh) |
WO (1) | WO2006138744A2 (zh) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1996233A2 (en) * | 2006-02-27 | 2008-12-03 | Gilead Colorado, Inc. | Combinations comprising a histone deacetylase inhibiting agent and a nuclear hormone receptor ligand for treating cardiovascular conditions |
UY30892A1 (es) * | 2007-02-07 | 2008-09-02 | Smithkline Beckman Corp | Inhibidores de la actividad akt |
MX2009011930A (es) | 2007-05-04 | 2009-11-18 | Vertex Pharma | Terapia de combinacion para el tratamiento de infeccion de virus de hepatitis c. |
CA2690192A1 (en) * | 2007-06-26 | 2008-12-31 | Gilead Colorado, Inc. | Imidazopyridinyl thiazolyl histone deacetylase inhibitors |
NZ590283A (en) * | 2008-07-14 | 2012-11-30 | Gilead Sciences Inc | Imidazolylpyrimidine compounds as hdac and / or cdk inhibitors |
US8344018B2 (en) * | 2008-07-14 | 2013-01-01 | Gilead Sciences, Inc. | Oxindolyl inhibitor compounds |
NZ590320A (en) * | 2008-07-14 | 2012-12-21 | Gilead Sciences Inc | Fused heterocyclyc inhibitors of histone deacetylase and/or cyclin-dependent kinases |
CN102123987A (zh) * | 2008-07-28 | 2011-07-13 | 吉里德科学公司 | 亚环烷基和亚杂环烷基组蛋白脱乙酰酶抑制剂化合物 |
HUE031580T2 (en) | 2008-08-15 | 2017-07-28 | Nivalis Therapeutics Inc | New pyrrole inhibitors of S-nitrosoglutathion reductase as therapeutic agents |
DK2315590T3 (da) | 2008-08-15 | 2012-11-19 | N30 Pharmaceuticals Inc | Pyrrolinhibitorer af S-nitrosoglutathionreduktase |
JP5688366B2 (ja) | 2008-08-15 | 2015-03-25 | エヌサーティー・ファーマシューティカルズ・インコーポレーテッド | 治療薬剤としての、s−ニトロソグルタチオンレダクターゼの新規ピロール阻害剤 |
PE20120003A1 (es) | 2009-01-30 | 2012-02-12 | Glaxosmithkline Llc | Hidrocloruro de n-{(1s)-2-amino-1-[(3-fluorofenil)metil)etil}-5-cloro-4-(4-cloro-1-metil-1h-pirazol-5-il)-2-tiofenocarboxamida cristalino |
JP2012529514A (ja) * | 2009-06-08 | 2012-11-22 | ギリアード サイエンシーズ, インコーポレイテッド | シクロアルキルカルバメートベンズアミドアニリンhdac阻害剤化合物 |
WO2010144371A1 (en) * | 2009-06-08 | 2010-12-16 | Gilead Colorado, Inc. | Alkanoylamino benzamide aniline hdac inihibitor compounds |
SG171708A1 (en) * | 2009-06-11 | 2011-07-28 | Abbott Lab | Anti-viral compounds to treat hcv infection |
US8822515B2 (en) | 2009-10-16 | 2014-09-02 | University Of Maryland, Baltimore County | Heterocyclic benzoxazole compositions as inhibitors of hepatitis C virus |
EA201200650A1 (ru) | 2009-10-30 | 2012-12-28 | Бёрингер Ингельхайм Интернациональ Гмбх | Курсы комбинированного лечения вируса гепатита с, включающие bi201335, интерферон-альфа и рибавирин |
TWI508968B (zh) * | 2010-02-08 | 2015-11-21 | Biota Scient Management | 用於治療呼吸道融合性病毒感染的化合物 |
EP2621495A1 (en) * | 2010-09-30 | 2013-08-07 | Boehringer Ingelheim International GmbH | Combination therapy for treating hcv infection |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4107288A (en) * | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
DE69133402T2 (de) * | 1990-04-04 | 2004-11-11 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Protease von hepatitis-c-virus |
US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
US5738985A (en) * | 1993-04-02 | 1998-04-14 | Ribogene, Inc. | Method for selective inactivation of viral replication |
IT1272179B (it) * | 1994-02-23 | 1997-06-16 | Angeletti P Ist Richerche Bio | Metodologia per riprodurre in vitro l'attivita' proteolitica della proteasi ns3 del virus hcv. |
US5861267A (en) * | 1995-05-01 | 1999-01-19 | Vertex Pharmaceuticals Incorporated | Methods, nucleotide sequences and host cells for assaying exogenous and endogenous protease activity |
US5759795A (en) * | 1996-03-08 | 1998-06-02 | Schering Corporation | Assay for determining inhibitors of ATPase |
EP0975809A4 (en) * | 1997-03-05 | 2002-10-30 | Univ Washington | EXAMINATION PROCEDURE FOR DETECTING AGENTS FOR SELECTIVE INHIBITION OF HCV REPLICATION |
EP1037974B1 (en) * | 1997-12-11 | 2007-10-03 | SmithKline Beecham Corporation | Hepatitis c virus ns5b truncated protein and methods thereof to identify antiviral compounds |
AR029803A1 (es) * | 2000-02-21 | 2003-07-16 | Smithkline Beecham Plc | Imidazoles sustituidos con piridilo y composiciones farmaceuticas que las comprenden |
EP2335700A1 (en) * | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C virus polymerase inhibitors with a heterobicylic structure |
MY151199A (en) * | 2001-11-02 | 2014-04-30 | Rigel Pharmaceuticals Inc | Substituted diphenyl heterocycles useful for treating hcv infection |
WO2004009017A2 (en) * | 2002-07-18 | 2004-01-29 | Bristol-Myers Squibb Company | Modulators of the glucocorticoid receptor and method |
GB0307891D0 (en) * | 2003-04-04 | 2003-05-14 | Angeletti P Ist Richerche Bio | Chemical compounds,compositions and uses |
TW200517381A (en) * | 2003-08-01 | 2005-06-01 | Genelabs Tech Inc | Bicyclic heteroaryl derivatives |
-
2006
- 2006-06-22 CA CA002613261A patent/CA2613261A1/en not_active Abandoned
- 2006-06-22 JP JP2008518457A patent/JP2008546802A/ja active Pending
- 2006-06-22 MA MA29128A patent/MA28394B1/fr unknown
- 2006-06-22 BR BRPI0612124-1A patent/BRPI0612124A2/pt not_active Application Discontinuation
- 2006-06-22 EP EP06799960A patent/EP1910337A2/en not_active Withdrawn
- 2006-06-22 CN CNA2006800262169A patent/CN101223161A/zh active Pending
- 2006-06-22 KR KR1020087001748A patent/KR20080040677A/ko not_active Application Discontinuation
- 2006-06-22 MX MX2007016144A patent/MX2007016144A/es not_active Application Discontinuation
- 2006-06-22 WO PCT/US2006/024554 patent/WO2006138744A2/en active Application Filing
- 2006-06-22 US US11/473,511 patent/US20060293320A1/en not_active Abandoned
- 2006-06-22 AU AU2006261132A patent/AU2006261132A1/en not_active Abandoned
- 2006-06-23 AR ARP060102719A patent/AR054797A1/es unknown
- 2006-06-23 PE PE2006000725A patent/PE20070124A1/es not_active Application Discontinuation
- 2006-06-23 TW TW095122749A patent/TW200726471A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
CA2613261A1 (en) | 2006-12-28 |
US20060293320A1 (en) | 2006-12-28 |
CN101223161A (zh) | 2008-07-16 |
WO2006138744A3 (en) | 2007-04-05 |
KR20080040677A (ko) | 2008-05-08 |
MX2007016144A (es) | 2008-03-06 |
AU2006261132A1 (en) | 2006-12-28 |
AR054797A1 (es) | 2007-07-18 |
JP2008546802A (ja) | 2008-12-25 |
WO2006138744A2 (en) | 2006-12-28 |
PE20070124A1 (es) | 2007-03-09 |
BRPI0612124A2 (pt) | 2010-10-19 |
MA28394B1 (fr) | 2007-01-02 |
EP1910337A2 (en) | 2008-04-16 |
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