TW200716104A - Tricyclic 6-alkylidene-penems as class-D β -lactamases inhibitors - Google Patents
Tricyclic 6-alkylidene-penems as class-D β -lactamases inhibitorsInfo
- Publication number
- TW200716104A TW200716104A TW095118171A TW95118171A TW200716104A TW 200716104 A TW200716104 A TW 200716104A TW 095118171 A TW095118171 A TW 095118171A TW 95118171 A TW95118171 A TW 95118171A TW 200716104 A TW200716104 A TW 200716104A
- Authority
- TW
- Taiwan
- Prior art keywords
- class
- tricyclic
- penems
- alkylidene
- lactam antibiotics
- Prior art date
Links
- 239000010752 BS 2869 Class D Substances 0.000 title abstract 3
- 108020004256 Beta-lactamase Proteins 0.000 title abstract 2
- 102000006635 beta-lactamase Human genes 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 239000003782 beta lactam antibiotic agent Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000002132 β-lactam antibiotic Substances 0.000 abstract 2
- 229940124586 β-lactam antibiotics Drugs 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010034133 Pathogen resistance Diseases 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68622105P | 2005-06-01 | 2005-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200716104A true TW200716104A (en) | 2007-05-01 |
Family
ID=37836305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW095118171A TW200716104A (en) | 2005-06-01 | 2006-05-22 | Tricyclic 6-alkylidene-penems as class-D β -lactamases inhibitors |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20060276446A1 (https=) |
| EP (1) | EP1885358A2 (https=) |
| JP (1) | JP2008542376A (https=) |
| CN (1) | CN101189010A (https=) |
| AR (1) | AR054467A1 (https=) |
| AU (1) | AU2006287938A1 (https=) |
| BR (1) | BRPI0611491A2 (https=) |
| CA (1) | CA2610478A1 (https=) |
| GT (1) | GT200600235A (https=) |
| MX (1) | MX2007015173A (https=) |
| PE (1) | PE20070010A1 (https=) |
| SV (1) | SV2007002555A (https=) |
| TW (1) | TW200716104A (https=) |
| WO (1) | WO2007030166A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR039475A1 (es) * | 2002-05-01 | 2005-02-23 | Wyeth Corp | 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa |
| AR039774A1 (es) * | 2002-05-01 | 2005-03-02 | Wyeth Corp | 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas |
| TW200716102A (en) * | 2005-06-01 | 2007-05-01 | Wyeth Corp | Bicyclic 6-alkylidene-penems as class-D β -lactamases inhibitors |
| US8945652B2 (en) | 2005-11-23 | 2015-02-03 | The Coca-Cola Company | High-potency sweetener for weight management and compositions sweetened therewith |
| US8524304B2 (en) * | 2005-11-23 | 2013-09-03 | The Coca-Cola Company | High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith |
| US8512789B2 (en) * | 2005-11-23 | 2013-08-20 | The Coca-Cola Company | High-potency sweetener composition with dietary fiber and compositions sweetened therewith |
| JP2012121809A (ja) * | 2009-02-26 | 2012-06-28 | Eisai R & D Management Co Ltd | 多環式化合物の製造法およびその中間体 |
| US20110288063A1 (en) * | 2010-05-19 | 2011-11-24 | Naeja Pharmaceutical Inc. | Novel fused bridged bicyclic heteroaryl substituted 6-alkylidene penems as potent beta-lactamase inhibitors |
| CN104341345B (zh) * | 2014-10-24 | 2016-03-23 | 海门海康生物医药科技有限公司 | 一种2-甲氧基-6-酮-5,6,7,8-四氢喹啉的合成方法 |
| WO2020179859A1 (ja) | 2019-03-06 | 2020-09-10 | 第一三共株式会社 | ピロロピラゾール誘導体 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9507521A (pt) * | 1994-04-25 | 1997-09-16 | Smithkline Beecham Plc | Formulação farmacêutica método para o tratemento de infecções bacterianas em seres humanos e animais uso de uma formulação e processo para sua preparação |
| US20040132706A1 (en) * | 2001-10-05 | 2004-07-08 | Daniela Salvemini | Composition comprising a catalyst for the dismutation of superoxide and use of the composition for preventing and treating hypotension |
| AR039476A1 (es) * | 2002-05-01 | 2005-02-23 | Wyeth Corp | Proceso para preparar derivados de 6-alquiliden penem |
| AR039475A1 (es) * | 2002-05-01 | 2005-02-23 | Wyeth Corp | 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa |
| AR039774A1 (es) * | 2002-05-01 | 2005-03-02 | Wyeth Corp | 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas |
| US20040132708A1 (en) * | 2002-05-01 | 2004-07-08 | Wyeth | Process for preparing 6-alkylidene penem derivatives |
| TW200716102A (en) * | 2005-06-01 | 2007-05-01 | Wyeth Corp | Bicyclic 6-alkylidene-penems as class-D β -lactamases inhibitors |
-
2006
- 2006-05-22 TW TW095118171A patent/TW200716104A/zh unknown
- 2006-05-25 CN CNA2006800193154A patent/CN101189010A/zh active Pending
- 2006-05-25 WO PCT/US2006/020410 patent/WO2007030166A2/en not_active Ceased
- 2006-05-25 AU AU2006287938A patent/AU2006287938A1/en not_active Abandoned
- 2006-05-25 JP JP2008514712A patent/JP2008542376A/ja not_active Withdrawn
- 2006-05-25 BR BRPI0611491-1A patent/BRPI0611491A2/pt not_active IP Right Cessation
- 2006-05-25 MX MX2007015173A patent/MX2007015173A/es unknown
- 2006-05-25 CA CA002610478A patent/CA2610478A1/en not_active Abandoned
- 2006-05-25 EP EP06824758A patent/EP1885358A2/en not_active Withdrawn
- 2006-05-31 US US11/444,346 patent/US20060276446A1/en not_active Abandoned
- 2006-05-31 SV SV2006002555A patent/SV2007002555A/es unknown
- 2006-05-31 PE PE2006000563A patent/PE20070010A1/es not_active Application Discontinuation
- 2006-06-01 AR ARP060102292A patent/AR054467A1/es unknown
- 2006-06-01 GT GT200600235A patent/GT200600235A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20060276446A1 (en) | 2006-12-07 |
| WO2007030166A2 (en) | 2007-03-15 |
| MX2007015173A (es) | 2008-02-15 |
| JP2008542376A (ja) | 2008-11-27 |
| AU2006287938A1 (en) | 2007-03-15 |
| BRPI0611491A2 (pt) | 2010-12-21 |
| CA2610478A1 (en) | 2007-03-15 |
| AR054467A1 (es) | 2007-06-27 |
| SV2007002555A (es) | 2007-02-02 |
| CN101189010A (zh) | 2008-05-28 |
| PE20070010A1 (es) | 2007-01-12 |
| WO2007030166A3 (en) | 2007-05-24 |
| EP1885358A2 (en) | 2008-02-13 |
| GT200600235A (es) | 2007-03-29 |
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