TW200641125A - Regulation of transcription with a cis-acting ribozyme - Google Patents

Regulation of transcription with a cis-acting ribozyme

Info

Publication number
TW200641125A
TW200641125A TW094116156A TW94116156A TW200641125A TW 200641125 A TW200641125 A TW 200641125A TW 094116156 A TW094116156 A TW 094116156A TW 94116156 A TW94116156 A TW 94116156A TW 200641125 A TW200641125 A TW 200641125A
Authority
TW
Taiwan
Prior art keywords
region
cis
sequence
transcription unit
transcription
Prior art date
Application number
TW094116156A
Other languages
English (en)
Inventor
xiao-bin Lu
Boro Dropulic
Vladimir Slepushkin
Gwendolyn Binder
Original Assignee
Virxsys Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virxsys Corp filed Critical Virxsys Corp
Publication of TW200641125A publication Critical patent/TW200641125A/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111General methods applicable to biologically active non-coding nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/12Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
    • C12N2310/121Hammerhead
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/12Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
    • C12N2310/127DNAzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16051Methods of production or purification of viral material
    • C12N2740/16052Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TW094116156A 2004-05-17 2005-05-18 Regulation of transcription with a cis-acting ribozyme TW200641125A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/847,728 US20050257277A1 (en) 2004-05-17 2004-05-17 Regulation of transcription with a cis-acting ribozyme

Publications (1)

Publication Number Publication Date
TW200641125A true TW200641125A (en) 2006-12-01

Family

ID=35310862

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094116156A TW200641125A (en) 2004-05-17 2005-05-18 Regulation of transcription with a cis-acting ribozyme

Country Status (8)

Country Link
US (1) US20050257277A1 (zh)
EP (1) EP1746877A4 (zh)
JP (1) JP2007537756A (zh)
CN (1) CN101094920A (zh)
AU (1) AU2005244907B2 (zh)
CA (1) CA2567251A1 (zh)
TW (1) TW200641125A (zh)
WO (1) WO2005112622A2 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103931566B (zh) * 2014-04-25 2016-08-17 浙江农林大学天目学院 一种诱导烟青虫滞育的方法
WO2019067322A1 (en) * 2017-09-26 2019-04-04 The Board Of Trustees Of The University Of Illinois CRISPR / CAS SYSTEM AND METHOD FOR GENOME EDITING AND TRANSCRIPTION MODULATION
CN113549641B (zh) * 2021-06-29 2023-12-22 复旦大学 一种核酶介导的多顺反子载体及其构建方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6522599A (en) * 1998-10-23 2000-05-15 Children's Medical Center Corporation Use of a self-cleaving rna motif to modulate gene expression
US20030026791A1 (en) * 2001-03-27 2003-02-06 Laurent Humeau Conditionally replicating vectors for inhibiting viral infections
JP4790984B2 (ja) * 2001-09-06 2011-10-12 アルファヴァックス,インコーポレイテッド アルファウイルスレプリコンベクター系

Also Published As

Publication number Publication date
WO2005112622A3 (en) 2007-05-24
CA2567251A1 (en) 2005-12-01
US20050257277A1 (en) 2005-11-17
AU2005244907B2 (en) 2011-04-07
CN101094920A (zh) 2007-12-26
AU2005244907A1 (en) 2005-12-01
EP1746877A2 (en) 2007-01-31
JP2007537756A (ja) 2007-12-27
WO2005112622A2 (en) 2005-12-01
EP1746877A4 (en) 2010-01-27

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