TW200632099A - Automated extraction and purification of samples using optical tweezers - Google Patents

Automated extraction and purification of samples using optical tweezers

Info

Publication number
TW200632099A
TW200632099A TW094143876A TW94143876A TW200632099A TW 200632099 A TW200632099 A TW 200632099A TW 094143876 A TW094143876 A TW 094143876A TW 94143876 A TW94143876 A TW 94143876A TW 200632099 A TW200632099 A TW 200632099A
Authority
TW
Taiwan
Prior art keywords
sample
channel
optical tweezers
purification
samples
Prior art date
Application number
TW094143876A
Other languages
English (en)
Inventor
Joseph S Plewa
Evan B Tanner
Daniel M Mueth
Crystal Duke
Kevin J Ehrenreich
Original Assignee
Arryx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arryx Inc filed Critical Arryx Inc
Publication of TW200632099A publication Critical patent/TW200632099A/zh

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/32—Micromanipulators structurally combined with microscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • G01N15/1433—
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/32—Holograms used as optical elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • G01N15/149—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N2001/002—Devices for supplying or distributing samples to an analysing apparatus
    • G01N2001/007—Devices specially adapted for forensic samples, e.g. tamper-proofing, sample tracking
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N2015/1454—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement using phase shift or interference, e.g. for improving contrast
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
TW094143876A 2004-12-10 2005-12-12 Automated extraction and purification of samples using optical tweezers TW200632099A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63516404P 2004-12-10 2004-12-10
US63498004P 2004-12-13 2004-12-13

Publications (1)

Publication Number Publication Date
TW200632099A true TW200632099A (en) 2006-09-16

Family

ID=36578664

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094143876A TW200632099A (en) 2004-12-10 2005-12-12 Automated extraction and purification of samples using optical tweezers

Country Status (5)

Country Link
US (2) US7875845B2 (zh)
EP (2) EP1838866A4 (zh)
JP (1) JP4904286B2 (zh)
TW (1) TW200632099A (zh)
WO (1) WO2006063335A2 (zh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010144814A2 (en) * 2009-06-13 2010-12-16 Arryx, Inc. Particle sorting using fluid streams
US20110177547A1 (en) * 2004-12-10 2011-07-21 Arryx, Inc. Particle Sorting Using Fluid Streams
US8169600B2 (en) 2006-09-15 2012-05-01 Arryx, Inc. Surface mapping by optical manipulation of particles in relation to a functionalized surface
GB0618605D0 (en) * 2006-09-21 2006-11-01 Univ St Andrews Optical sorting
JP2008199919A (ja) * 2007-02-16 2008-09-04 Kyushu Univ 細胞選別分取方法および装置
US8067170B2 (en) * 2007-09-11 2011-11-29 Arryx, Inc. Binding method and apparatus for sorting objects
CN101801491A (zh) * 2007-09-13 2010-08-11 阿尔利克斯公司 用于在法医dna分析和医学诊断中分选物体的方法和设备
GB0813090D0 (en) * 2008-07-17 2008-08-27 Univ St Andrews Optical trap
WO2010101671A1 (en) 2009-01-16 2010-09-10 New York University Automated real-time particle characterization and three-dimensional velocimetry with holographic video microscopy
DE102008060332B4 (de) * 2008-12-03 2013-01-10 Albert-Ludwigs-Universität Freiburg Verfahren zum Sortieren von mindestens einem Partikel mit einer mikrofluidischen Sortiervorrichtung mit optischer Pinzette
CN102753954A (zh) 2009-12-22 2012-10-24 纽约大学 利用光学力将胶粒分成多个通道：棱镜光学分离
WO2012037642A1 (en) 2010-08-20 2012-03-29 Marksmen Cellject Inc. System and method for automated sperm manipulation
US8723104B2 (en) * 2012-09-13 2014-05-13 City University Of Hong Kong Methods and means for manipulating particles
ES2913524T3 (es) 2014-11-12 2022-06-02 Univ New York Huellas coloidales para materiales blandos usando caracterización holográfica total
DE102015116391B4 (de) 2015-09-28 2017-04-27 Marion Vollmer Medizinische Vorrichtung für die selektive Separierung einer biologischen Probe
EP3414517B1 (en) 2016-02-08 2021-10-06 New York University Holographic characterization of protein aggregates
US10611995B2 (en) * 2018-08-15 2020-04-07 Deepcell, Inc. Systems and methods for particle analysis
CN110331125B (zh) * 2019-06-28 2023-04-07 南京航空航天大学 一种自动化实现多组细胞配对方法
KR102266834B1 (ko) * 2019-08-13 2021-06-17 경희대학교 산학협력단 정자 처리를 위한 미세유체장치
US11543338B2 (en) 2019-10-25 2023-01-03 New York University Holographic characterization of irregular particles
US11948302B2 (en) 2020-03-09 2024-04-02 New York University Automated holographic video microscopy assay
CN116013575B (zh) * 2022-12-21 2023-08-22 深圳大学 一种基于水反常膨胀特性的低温光热镊操控系统及方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1311404C (en) 1987-03-13 1992-12-15 Kenneth H. Kortright Automated analyzer and method for screening cells or formed bodies for enumeration of populations expressing selected characteristics
US5392155A (en) 1988-06-17 1995-02-21 Tamari; Vladimir F. De-diffraction methods
US6005964A (en) 1996-01-24 1999-12-21 The Board Of Trustees Of The University Of Illinois Automatic machine vision microscope slide inspection system and method
US6055106A (en) * 1998-02-03 2000-04-25 Arch Development Corporation Apparatus for applying optical gradient forces
DE19952322C2 (de) 1999-10-29 2002-06-13 Evotec Ag Verfahren und Vorrichtung zur Partikeltrennung
US20020108859A1 (en) * 2000-11-13 2002-08-15 Genoptix Methods for modifying interaction between dielectric particles and surfaces
US20020121443A1 (en) * 2000-11-13 2002-09-05 Genoptix Methods for the combined electrical and optical identification, characterization and/or sorting of particles
GB2371858B (en) * 2001-02-05 2004-10-13 Abb Offshore Systems Ltd Monitoring particles in a fluid flow
WO2003008943A1 (en) * 2001-07-19 2003-01-30 Tufts University Optical array device and methods of use thereof for screening, analysis and manipulation of particles
US7150834B2 (en) * 2003-07-31 2006-12-19 Arryx, Inc. Multiple laminar flow-based rate zonal or isopycnic separation with holographic optical trapping of blood cells and other static components
EP2806427A3 (en) 2002-07-31 2015-04-22 Premium Genetics (UK) Limited System and method of sorting materials using holographic laser steering
DE10313760B3 (de) 2003-03-27 2004-06-03 Fresenius Kabi Deutschland Gmbh Konnektor für medizinische Flüssigkeiten enthaltende Verpackungen und Verpackung für medizinische Flüssigkeiten

Also Published As

Publication number Publication date
EP1838866A4 (en) 2010-04-14
US20110091932A1 (en) 2011-04-21
JP4904286B2 (ja) 2012-03-28
JP2008530981A (ja) 2008-08-14
WO2006063335A2 (en) 2006-06-15
US7875845B2 (en) 2011-01-25
EP1838866A2 (en) 2007-10-03
WO2006063335A3 (en) 2009-04-16
EP2573543A2 (en) 2013-03-27
US20060134603A1 (en) 2006-06-22

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