TW200612945A - Aerosol suspension formulations containing TG 227 ea as propellant - Google Patents

Aerosol suspension formulations containing TG 227 ea as propellant

Info

Publication number
TW200612945A
TW200612945A TW094122245A TW94122245A TW200612945A TW 200612945 A TW200612945 A TW 200612945A TW 094122245 A TW094122245 A TW 094122245A TW 94122245 A TW94122245 A TW 94122245A TW 200612945 A TW200612945 A TW 200612945A
Authority
TW
Taiwan
Prior art keywords
propellant
formulations containing
suspension formulations
aerosol suspension
water
Prior art date
Application number
TW094122245A
Other languages
English (en)
Other versions
TWI377943B (en
Inventor
Christel Schmelzer
Arne Froemder
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35169696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200612945(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE102004032322A external-priority patent/DE102004032322A1/de
Priority claimed from DE200510023334 external-priority patent/DE102005023334A1/de
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of TW200612945A publication Critical patent/TW200612945A/zh
Application granted granted Critical
Publication of TWI377943B publication Critical patent/TWI377943B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW094122245A 2004-07-02 2005-07-01 Aerosol suspension formulations containing tg 227 ea as propellant TWI377943B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004032322A DE102004032322A1 (de) 2004-07-02 2004-07-02 Aerosolsuspensionsformulierungen mit TG 227 ea als Teibmittel
DE200510023334 DE102005023334A1 (de) 2005-05-17 2005-05-17 Aeorosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel

Publications (2)

Publication Number Publication Date
TW200612945A true TW200612945A (en) 2006-05-01
TWI377943B TWI377943B (en) 2012-12-01

Family

ID=35169696

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094122245A TWI377943B (en) 2004-07-02 2005-07-01 Aerosol suspension formulations containing tg 227 ea as propellant

Country Status (19)

Country Link
US (1) US8357352B2 (zh)
EP (1) EP1809243B2 (zh)
JP (1) JP5209963B2 (zh)
KR (1) KR101297061B1 (zh)
AR (1) AR049660A1 (zh)
AU (1) AU2005259523B2 (zh)
BR (1) BRPI0512878A (zh)
CA (1) CA2571519C (zh)
DK (1) DK1809243T4 (zh)
EA (1) EA013428B1 (zh)
EC (1) ECSP077126A (zh)
ES (1) ES2391563T5 (zh)
IL (1) IL180461A0 (zh)
MX (1) MXPA06015204A (zh)
NO (1) NO20070373L (zh)
NZ (1) NZ552869A (zh)
PL (1) PL1809243T5 (zh)
TW (1) TWI377943B (zh)
WO (1) WO2006002840A2 (zh)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0512878A (pt) 2004-07-02 2008-04-15 Boehringer Ingelheim Int formulações de suspensão de aerossol, com tg 227 ea ou tg 134 a como agente propulsor
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
DE102006053374A1 (de) * 2006-02-09 2007-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
WO2008047239A2 (en) * 2006-09-21 2008-04-24 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
GB2442745B (en) 2006-10-13 2011-04-06 At & T Corp Method and apparatus for acoustic sensing using multiple optical pulses
GB2442746B (en) * 2006-10-13 2011-04-06 At & T Corp Method and apparatus for acoustic sensing using multiple optical pulses
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
EP3695835A1 (en) * 2009-02-03 2020-08-19 Microbion Corporation Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
WO2010133294A2 (de) 2009-05-18 2010-11-25 Boehringer Ingelheim International Gmbh Adapter, inhalationseinrichtung und zerstäuber
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011064164A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
JP6335798B2 (ja) 2012-02-28 2018-05-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規噴射剤含有チオトロピウム製剤
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
WO2015018904A1 (en) 2013-08-09 2015-02-12 Boehringer Ingelheim International Gmbh Nebulizer
US10195374B2 (en) 2014-05-07 2019-02-05 Boehringer Ingelheim International Gmbh Container, nebulizer and use
CN106232166B (zh) 2014-05-07 2020-04-14 勃林格殷格翰国际有限公司 喷雾器
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
US10322198B2 (en) 2016-07-08 2019-06-18 The Procter & Gamble Company Freshening compositions comprising isopropyl myristate

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8824804D0 (en) * 1988-10-22 1988-11-30 Fisons Plc Device
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
DE4003270A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgase und ihre verwendung in arzneimittelzubereitungen
US5919435A (en) * 1990-11-09 1999-07-06 Glaxo Group Limited Aerosol formulation containing a particulate medicament
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
GB9202519D0 (en) * 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
UA27143C2 (uk) * 1992-12-09 2000-02-28 Берінгер Інгельхейм Фармасьютікалс Інк Рідка фармацевтичhа композиція в формі аерозолю
EP0697002B1 (en) * 1993-04-30 1997-11-19 Minnesota Mining And Manufacturing Company Seal configuration for aerosol canister
CA2166970C (en) * 1993-07-15 2000-12-19 Oh-Seung Kwon Seals for use in an aerosol delivery device
US6149892A (en) * 1995-04-14 2000-11-21 Glaxowellcome, Inc. Metered dose inhaler for beclomethasone dipropionate
GB9513084D0 (en) 1995-06-27 1995-08-30 Bespak Plc Dispensing apparatus
SE9701750D0 (sv) * 1997-05-12 1997-05-12 Astra Pharma Prod Inhalation device and method of manufacture thereof
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
GB2326334A (en) 1997-06-13 1998-12-23 Chiesi Farma Spa Pharmaceutical aerosol compositions
JP3801348B2 (ja) 1997-07-28 2006-07-26 株式会社ヴァレオサーマルシステムズ レシーバタンク
JP4117059B2 (ja) * 1998-02-10 2008-07-09 東洋エアゾール工業株式会社 高濃度粉末エアゾール製品
US6423298B2 (en) * 1998-06-18 2002-07-23 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical formulations for aerosols with two or more active substances
ATE234604T1 (de) * 1998-08-04 2003-04-15 Jago Res Ag Medizinische aerosolformulierungen
US5955958A (en) 1998-10-05 1999-09-21 Lu; Kai Holiday candy jar with light and sound effects
IT1303788B1 (it) 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6261539B1 (en) 1998-12-10 2001-07-17 Akwete Adjei Medicinal aerosol formulation
US6739333B1 (en) * 1999-05-26 2004-05-25 Boehringer Ingelheim Pharma Kg Stainless steel canister for propellant-driven metering aerosols
GB0002798D0 (en) * 2000-02-09 2000-03-29 Glaxo Group Ltd Actuator nozzle for metered dose inhaler
AU2001281288A1 (en) * 2000-07-18 2002-01-30 Aeropharm Technology Incorporated Modulated release therapeutic aerosols
EP1311294A2 (en) * 2000-08-04 2003-05-21 Longwood Pharmaceutical Research, Inc. Formulations of mometasone and a bronchodilator for pulmonary administration
DE10043509A1 (de) * 2000-09-01 2002-03-14 Asta Medica Ag Feste Peptidzubereitungen für die Inhalation und deren Herstellung
US7776315B2 (en) * 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
EP1241113A1 (en) 2001-03-12 2002-09-18 CHIESI FARMACEUTICI S.p.A. Inhaler with means for improving chemical stability of medicinal aerosol solution contained therein
CA2452140C (en) 2001-06-26 2010-12-14 Norton Healthcare, Ltd. An improved aerosol actuator
US20050118107A1 (en) * 2002-02-01 2005-06-02 Steve Burns Composition for inhalation
EP3384931B1 (en) * 2002-03-01 2019-07-24 Chiesi Farmaceutici S.p.A. Formoterol superfine formulation
EP1340492A1 (en) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Aerosol formulations for pulmonary administration of medicaments having systemic effects
DE10214263A1 (de) 2002-03-28 2003-10-16 Boehringer Ingelheim Pharma HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum
ATE422197T1 (de) * 2002-11-22 2009-02-15 Lilly Co Eli Modulatoren von vitamin d rezeptoren
KR101113003B1 (ko) * 2003-03-20 2012-02-24 베링거 인겔하임 파마슈티칼즈, 인코포레이티드 추진제로 하이드로-플루오로-알칸을 사용하는 계량 흡입기용 제형
AR041873A1 (es) * 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
BRPI0512878A (pt) 2004-07-02 2008-04-15 Boehringer Ingelheim Int formulações de suspensão de aerossol, com tg 227 ea ou tg 134 a como agente propulsor
DE102004032322A1 (de) 2004-07-02 2006-02-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea als Teibmittel
NZ555500A (en) 2004-12-17 2010-09-30 Cipla Ltd Crystalline forms of levosalbutamol sulfate, process for their preparation, and their use in respiratory conditions
DE102006053374A1 (de) * 2006-02-09 2007-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz
DE102006017320A1 (de) * 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel

Also Published As

Publication number Publication date
DK1809243T4 (da) 2022-09-05
WO2006002840A2 (de) 2006-01-12
US20060002863A1 (en) 2006-01-05
AU2005259523A1 (en) 2006-01-12
ES2391563T5 (es) 2022-10-26
ES2391563T3 (es) 2012-11-27
WO2006002840A8 (de) 2012-11-08
EP1809243B8 (de) 2013-02-27
KR101297061B1 (ko) 2013-08-19
PL1809243T3 (pl) 2013-05-31
EP1809243A2 (de) 2007-07-25
NO20070373L (no) 2007-01-31
EA200700042A1 (ru) 2007-08-31
US8357352B2 (en) 2013-01-22
IL180461A0 (en) 2007-06-03
EP1809243B1 (de) 2012-07-18
NZ552869A (en) 2010-06-25
MXPA06015204A (es) 2007-03-15
WO2006002840A3 (de) 2006-11-16
CA2571519C (en) 2013-05-14
CA2571519A1 (en) 2006-01-12
JP2008504325A (ja) 2008-02-14
ECSP077126A (es) 2007-02-28
AR049660A1 (es) 2006-08-23
TWI377943B (en) 2012-12-01
JP5209963B2 (ja) 2013-06-12
KR20070042166A (ko) 2007-04-20
PL1809243T5 (pl) 2022-12-27
AU2005259523B2 (en) 2011-06-09
DK1809243T3 (da) 2012-10-15
EA013428B1 (ru) 2010-04-30
EP1809243B2 (de) 2022-06-08
BRPI0512878A (pt) 2008-04-15

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