TW200517360A - Process for preparing radioactive fluorine compounds - Google Patents

Process for preparing radioactive fluorine compounds

Info

Publication number
TW200517360A
TW200517360A TW093134320A TW93134320A TW200517360A TW 200517360 A TW200517360 A TW 200517360A TW 093134320 A TW093134320 A TW 093134320A TW 93134320 A TW93134320 A TW 93134320A TW 200517360 A TW200517360 A TW 200517360A
Authority
TW
Taiwan
Prior art keywords
column
substrate
fluoride ions
labeled
fluorine compounds
Prior art date
Application number
TW093134320A
Other languages
English (en)
Inventor
Keiichi Hirano
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Publication of TW200517360A publication Critical patent/TW200517360A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
TW093134320A 2003-11-11 2004-11-10 Process for preparing radioactive fluorine compounds TW200517360A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003381032 2003-11-11

Publications (1)

Publication Number Publication Date
TW200517360A true TW200517360A (en) 2005-06-01

Family

ID=34567262

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093134320A TW200517360A (en) 2003-11-11 2004-11-10 Process for preparing radioactive fluorine compounds

Country Status (7)

Country Link
US (1) US20070071671A1 (zh)
EP (1) EP1683776A4 (zh)
JP (1) JP4519774B2 (zh)
AU (1) AU2004287704B2 (zh)
NZ (1) NZ546260A (zh)
TW (1) TW200517360A (zh)
WO (1) WO2005044758A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2017359A3 (en) * 2007-06-11 2009-08-05 Trasis S.A. Method for the elution of 18F fluoride trapped on an anion-exchange resin in a form suitable for efficient radiolabeling without any evaporation step
EP1990310A1 (en) * 2007-04-23 2008-11-12 Trasis S.A. Method for the preparation of reactive 18F fluoride, and for the labeling of radiotracers, using a modified non-ionic solid support and without any evaporation step
EP2062630A1 (en) * 2007-11-20 2009-05-27 Trasis S.A. Method for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium by the use of strong organic bases
CA2729973A1 (en) * 2008-07-07 2010-01-14 Bayer Schering Pharma Aktiengesellschaft Process for production of radiopharmaceuticals
WO2010072342A2 (en) * 2008-12-22 2010-07-01 Bayer Schering Pharma Aktiengesellschaft A method for the synthesis of a radionuclide-labeled compound
JP7424574B2 (ja) * 2018-08-22 2024-01-30 国立大学法人北海道大学 放射性フッ素標識化合物の製造方法及び放射性医薬組成物の製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2576264A (en) * 1947-08-16 1951-11-27 Univ Minnesota Spray drying apparatus
EP0641350A4 (en) * 1993-03-22 1995-08-23 Gen Electric METHOD FOR PRODUCING 2-FLUORO-2-DESOXYGLUCOSE.
JPH08325169A (ja) * 1995-03-29 1996-12-10 Nkk Corp フッ素放射性同位元素標識有機化合物の製造方法
JPH08325168A (ja) * 1995-03-29 1996-12-10 Nkk Corp フッ素放射性同位元素標識有機化合物の製造方法
JP3133253B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 標識反応および加水分解反応をカラムで行うｆｄｇ合成装置
US5932178A (en) * 1996-03-29 1999-08-03 Nkk Plant Engineering Corporation FDG synthesizer using columns
JP3279914B2 (ja) * 1996-03-29 2002-04-30 エヌケ−ケ−プラント建設株式会社 オンカラムｆｄｇ合成装置
CA2399429A1 (en) * 2000-02-09 2001-08-16 Riken Method of separating and recovering 18f in 18o water

Also Published As

Publication number Publication date
EP1683776A1 (en) 2006-07-26
US20070071671A1 (en) 2007-03-29
JPWO2005044758A1 (ja) 2007-11-29
EP1683776A4 (en) 2007-08-29
AU2004287704B2 (en) 2008-01-17
AU2004287704A1 (en) 2005-05-19
NZ546260A (en) 2009-06-26
WO2005044758A1 (ja) 2005-05-19
JP4519774B2 (ja) 2010-08-04

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