CA2482294A1 - Multicolumn selectivity inversion generator for production of ultrapure radionuclides - Google Patents

Multicolumn selectivity inversion generator for production of ultrapure radionuclides Download PDF

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Publication number
CA2482294A1
CA2482294A1 CA002482294A CA2482294A CA2482294A1 CA 2482294 A1 CA2482294 A1 CA 2482294A1 CA 002482294 A CA002482294 A CA 002482294A CA 2482294 A CA2482294 A CA 2482294A CA 2482294 A1 CA2482294 A1 CA 2482294A1
Authority
CA
Canada
Prior art keywords
radionuclides
ultrapure
production
solution
inversion generator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002482294A
Other languages
French (fr)
Other versions
CA2482294C (en
Inventor
Philip E. Horwitz
Andrew H. Bond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PG Research Foundation Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/159,003 external-priority patent/US6852296B2/en
Priority claimed from US10/261,031 external-priority patent/US7087206B2/en
Priority claimed from US10/351,717 external-priority patent/US7157022B2/en
Priority claimed from US10/409,829 external-priority patent/US6998052B2/en
Application filed by Individual filed Critical Individual
Publication of CA2482294A1 publication Critical patent/CA2482294A1/en
Application granted granted Critical
Publication of CA2482294C publication Critical patent/CA2482294C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G4/00—Radioactive sources
    • G21G4/04—Radioactive sources other than neutron sources
    • G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
    • G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/0005—Isotope delivery systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Disclosed is a process for producing a solution of a daughter radionuclide that is substantially free of impurities by contacting an aqueous parent-daughter radionuclide solution with a first separation medium, eg.
Chromatographic column. The product solution of the desired daughter radionuclide is then contacted with a second separation medium to produce a pure daughter radionuclide solution.
CA002482294A 2002-04-12 2003-04-10 Multicolumn selectivity inversion generator for production of ultrapure radionuclides Expired - Lifetime CA2482294C (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US37232702P 2002-04-12 2002-04-12
US60/372,327 2002-04-12
US10/159,003 2002-05-31
US10/159,003 US6852296B2 (en) 2001-06-22 2002-05-31 Production of ultrapure bismuth-213 for use in therapeutic nuclear medicine
US10/261,031 US7087206B2 (en) 2002-04-12 2002-09-30 Multicolumn selectivity inversion generator for production of high purity actinium for use in therapeutic nuclear medicine
US10/261,031 2002-09-30
US10/351,717 2003-01-27
US10/351,717 US7157022B2 (en) 2002-09-30 2003-01-27 Multivalent metal ion extraction using diglycolamide-coated particles
US10/409,829 US6998052B2 (en) 2002-04-12 2003-04-09 Multicolumn selectivity inversion generator for production of ultrapure radionuclides
US10/409,829 2003-04-09
PCT/US2003/011278 WO2003086569A1 (en) 2002-04-12 2003-04-10 Multicolumn selectivity inversion generator for production of ultrapure radionuclides

Publications (2)

Publication Number Publication Date
CA2482294A1 true CA2482294A1 (en) 2003-10-23
CA2482294C CA2482294C (en) 2008-03-11

Family

ID=29255665

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002482294A Expired - Lifetime CA2482294C (en) 2002-04-12 2003-04-10 Multicolumn selectivity inversion generator for production of ultrapure radionuclides

Country Status (6)

Country Link
EP (1) EP1499412B1 (en)
CN (1) CN1327926C (en)
AU (1) AU2003230886B2 (en)
CA (1) CA2482294C (en)
WO (1) WO2003086569A1 (en)
ZA (1) ZA200408384B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2131369A1 (en) * 2008-06-06 2009-12-09 Technische Universiteit Delft A process for the production of no-carrier added 99Mo
CN103454364B (en) * 2012-05-28 2015-12-09 原子高科股份有限公司 Chromatographic column device for generator
GB201314718D0 (en) * 2013-08-16 2013-10-02 Algeta As Quantification method
GB201317553D0 (en) * 2013-10-03 2013-11-20 Univ Central Lancashire Chromatographic Separation of Nuclear Waste
JP6465273B2 (en) * 2014-09-24 2019-02-06 日東電工株式会社 Rare earth element adsorption separation material
EP3174068B1 (en) 2015-11-30 2018-06-20 Orano Med New method and apparatus for the production of high purity radionuclides
CN112962125B (en) * 2021-02-09 2022-05-17 原子高科股份有限公司 Method for preparing 64Ni target and 64Cu nuclide and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5154897A (en) * 1991-03-06 1992-10-13 University Of Missouri Method and apparatus for the generation of radioisotopes
US5368736A (en) * 1993-07-26 1994-11-29 The United States Of America As Represented By The United States Department Of Energy Process for the separation and purification of yttrium-90 for medical applications
CA2261772C (en) * 1996-08-26 2003-12-09 Paul V. Harper Process and apparatus for the production of bi-212 and a use thereof
US5809394A (en) * 1996-12-13 1998-09-15 Battelle Memorial Institute Methods of separating short half-life radionuclides from a mixture of radionuclides
JP4495453B2 (en) 2001-06-22 2010-07-07 ピージー リサーチ ファンデーション，インコーポレーテッド Automatic radionuclide separation system

Also Published As

Publication number Publication date
CA2482294C (en) 2008-03-11
EP1499412A4 (en) 2007-07-11
CN1658938A (en) 2005-08-24
WO2003086569A1 (en) 2003-10-23
AU2003230886A1 (en) 2003-10-27
AU2003230886B2 (en) 2007-07-05
EP1499412B1 (en) 2014-06-11
ZA200408384B (en) 2005-11-30
CN1327926C (en) 2007-07-25
EP1499412A1 (en) 2005-01-26

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MKEX Expiry

Effective date: 20230411