CA2482294A1 - Generateur multicolonnes a inversion de selectivite pour la production de radionucleides ultrapurs - Google Patents

Generateur multicolonnes a inversion de selectivite pour la production de radionucleides ultrapurs Download PDF

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Publication number
CA2482294A1
CA2482294A1 CA002482294A CA2482294A CA2482294A1 CA 2482294 A1 CA2482294 A1 CA 2482294A1 CA 002482294 A CA002482294 A CA 002482294A CA 2482294 A CA2482294 A CA 2482294A CA 2482294 A1 CA2482294 A1 CA 2482294A1
Authority
CA
Canada
Prior art keywords
radionuclides
ultrapure
production
solution
inversion generator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002482294A
Other languages
English (en)
Other versions
CA2482294C (fr
Inventor
Philip E. Horwitz
Andrew H. Bond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PG Research Foundation Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/159,003 external-priority patent/US6852296B2/en
Priority claimed from US10/261,031 external-priority patent/US7087206B2/en
Priority claimed from US10/351,717 external-priority patent/US7157022B2/en
Priority claimed from US10/409,829 external-priority patent/US6998052B2/en
Application filed by Individual filed Critical Individual
Publication of CA2482294A1 publication Critical patent/CA2482294A1/fr
Application granted granted Critical
Publication of CA2482294C publication Critical patent/CA2482294C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G4/00—Radioactive sources
    • G21G4/04—Radioactive sources other than neutron sources
    • G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
    • G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/0005—Isotope delivery systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne un procédé de production d'une solution de radionucléide de filiation sensiblement exempte d'impuretés par contact d'une solution de radionucléide de filiation parente aqueuse avec un premier milieu de séparation, par exemple une colonne chromatographique. La solution de produit du radionucléide de filiation voulu est ensuite mise en contact avec un second milieu de séparation pour produire une solution de radionucléide de filiation pure.
CA002482294A 2002-04-12 2003-04-10 Generateur multicolonnes a inversion de selectivite pour la production de radionucleides ultrapurs Expired - Lifetime CA2482294C (fr)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US37232702P 2002-04-12 2002-04-12
US60/372,327 2002-04-12
US10/159,003 2002-05-31
US10/159,003 US6852296B2 (en) 2001-06-22 2002-05-31 Production of ultrapure bismuth-213 for use in therapeutic nuclear medicine
US10/261,031 US7087206B2 (en) 2002-04-12 2002-09-30 Multicolumn selectivity inversion generator for production of high purity actinium for use in therapeutic nuclear medicine
US10/261,031 2002-09-30
US10/351,717 US7157022B2 (en) 2002-09-30 2003-01-27 Multivalent metal ion extraction using diglycolamide-coated particles
US10/351,717 2003-01-27
US10/409,829 2003-04-09
US10/409,829 US6998052B2 (en) 2002-04-12 2003-04-09 Multicolumn selectivity inversion generator for production of ultrapure radionuclides
PCT/US2003/011278 WO2003086569A1 (fr) 2002-04-12 2003-04-10 Generateur multicolonnes a inversion de selectivite pour la production de radionucleides ultrapurs

Publications (2)

Publication Number Publication Date
CA2482294A1 true CA2482294A1 (fr) 2003-10-23
CA2482294C CA2482294C (fr) 2008-03-11

Family

ID=29255665

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002482294A Expired - Lifetime CA2482294C (fr) 2002-04-12 2003-04-10 Generateur multicolonnes a inversion de selectivite pour la production de radionucleides ultrapurs

Country Status (6)

Country Link
EP (1) EP1499412B1 (fr)
CN (1) CN1327926C (fr)
AU (1) AU2003230886B2 (fr)
CA (1) CA2482294C (fr)
WO (1) WO2003086569A1 (fr)
ZA (1) ZA200408384B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2131369A1 (fr) * 2008-06-06 2009-12-09 Technische Universiteit Delft Procédé de production de 99-Mo sans support ajouté
CN103454364B (zh) * 2012-05-28 2015-12-09 原子高科股份有限公司 一种用于发生器的色谱柱装置
GB201314718D0 (en) * 2013-08-16 2013-10-02 Algeta As Quantification method
GB201317553D0 (en) * 2013-10-03 2013-11-20 Univ Central Lancashire Chromatographic Separation of Nuclear Waste
JP6465273B2 (ja) * 2014-09-24 2019-02-06 日東電工株式会社 希土類元素の吸着分離材
EP3174068B1 (fr) 2015-11-30 2018-06-20 Orano Med Nouveau procédé et appareil pour la production de radionucléides de haute pureté
CN112962125B (zh) * 2021-02-09 2022-05-17 原子高科股份有限公司 一种制备64Ni靶件、64Cu核素的方法与其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5154897A (en) * 1991-03-06 1992-10-13 University Of Missouri Method and apparatus for the generation of radioisotopes
US5368736A (en) * 1993-07-26 1994-11-29 The United States Of America As Represented By The United States Department Of Energy Process for the separation and purification of yttrium-90 for medical applications
CA2261772C (fr) * 1996-08-26 2003-12-09 Paul V. Harper Procede et appareillage destines a produire du bi-212 et une utilisation de ceux-ci
US5809394A (en) * 1996-12-13 1998-09-15 Battelle Memorial Institute Methods of separating short half-life radionuclides from a mixture of radionuclides
JP4495453B2 (ja) * 2001-06-22 2010-07-07 ピージー リサーチ ファンデーション，インコーポレーテッド 自動放射性核種分離システム

Also Published As

Publication number Publication date
CA2482294C (fr) 2008-03-11
EP1499412A4 (fr) 2007-07-11
WO2003086569A1 (fr) 2003-10-23
CN1327926C (zh) 2007-07-25
AU2003230886A1 (en) 2003-10-27
AU2003230886B2 (en) 2007-07-05
ZA200408384B (en) 2005-11-30
EP1499412B1 (fr) 2014-06-11
CN1658938A (zh) 2005-08-24
EP1499412A1 (fr) 2005-01-26

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Effective date: 20230411