TR201908019T4 - Doğum öncesi teşhis için servikal mukusta fetal trofoblast hücrelerinin tanımlanması ve analizi. - Google Patents

Doğum öncesi teşhis için servikal mukusta fetal trofoblast hücrelerinin tanımlanması ve analizi. Download PDF

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Publication number
TR201908019T4
TR201908019T4 TR2019/08019T TR201908019T TR201908019T4 TR 201908019 T4 TR201908019 T4 TR 201908019T4 TR 2019/08019 T TR2019/08019 T TR 2019/08019T TR 201908019 T TR201908019 T TR 201908019T TR 201908019 T4 TR201908019 T4 TR 201908019T4
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cells
fetal
sample
trophoblast
analysis
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TR2019/08019T
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English (en)
Turkish (tr)
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Randall Armant D
P Diamond Michael
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Univ Wayne State
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Publication of TR201908019T4 publication Critical patent/TR201908019T4/tr

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0605Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539MHC-molecules, e.g. HLA-molecules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • G01N2800/368Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
TR2019/08019T 2012-10-19 2013-10-18 Doğum öncesi teşhis için servikal mukusta fetal trofoblast hücrelerinin tanımlanması ve analizi. TR201908019T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261715854P 2012-10-19 2012-10-19

Publications (1)

Publication Number Publication Date
TR201908019T4 true TR201908019T4 (tr) 2019-06-21

Family

ID=50488767

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TR2019/08019T TR201908019T4 (tr) 2012-10-19 2013-10-18 Doğum öncesi teşhis için servikal mukusta fetal trofoblast hücrelerinin tanımlanması ve analizi.

Country Status (10)

Country Link
US (1) US10344315B2 (enExample)
EP (1) EP2909315B1 (enExample)
JP (1) JP6421123B2 (enExample)
AU (1) AU2013331171B2 (enExample)
CA (1) CA2888746C (enExample)
DK (1) DK2909315T3 (enExample)
ES (1) ES2729182T3 (enExample)
IN (1) IN2015DN03186A (enExample)
TR (1) TR201908019T4 (enExample)
WO (1) WO2014062995A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2909315B1 (en) 2012-10-19 2019-05-01 Wayne State University Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis
DK3204536T3 (da) * 2014-10-10 2020-03-30 Univ Wayne State Fremgangsmåde til analyse af RNA fra føtale ekstravilløse trophoblastceller
AU2017246480B2 (en) * 2016-04-06 2023-06-01 Wayne State University Isolation and analysis of fetal DNA from extravillous trophoblast cells retrieved from the endocervical canal
EP3442706B1 (en) 2016-04-13 2025-07-23 NextGen Jane, Inc. Sample collection and preservation methods
WO2019021065A2 (en) * 2017-02-13 2019-01-31 Trophodiagnostics, Llc NEW SYSTEM AND METHOD FOR COLLECTING, ENRICHING AND ISOLATING TROPHOBLASTIC CELLS FROM A ENDOCERVICAL CHANNEL
US11230729B2 (en) 2018-04-20 2022-01-25 Inanna Diagnostics, Inc Methods and devices for obtaining cellular and DNA material from human female reproductive system
TWI668423B (zh) * 2018-10-02 2019-08-11 吳宏偉 細胞分選方法及系統
CN111122857A (zh) * 2018-10-31 2020-05-08 苏州浚惠生物科技有限公司 胎儿滋养层细胞的标志物、鉴定方法、检测试剂盒和应用
CN111304153A (zh) * 2019-12-17 2020-06-19 广东凯普生物科技股份有限公司 一种分离滋养层细胞的方法
JP7824649B2 (ja) * 2020-02-21 2026-03-05 国立大学法人東海国立大学機構 胎児発育不全に対する定量的評価指標
CN112980779B (zh) * 2021-05-20 2021-08-24 广州凯普医药科技有限公司 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法
AU2023406050A1 (en) * 2022-11-29 2025-06-12 Akna Health Inc. Identification of cervical biomarkers

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629147A (en) 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
EP0587951B1 (en) 1992-09-18 1997-12-17 AMERSHAM INTERNATIONAL plc Cell nuclei capture method and device used therefor
DE69941689D1 (de) * 1998-02-12 2010-01-07 Univ Texas Verfahren und reagenzien zur raschen und effizienten isolierung zirkulierender krebszellen
AUPR749901A0 (en) * 2001-09-06 2001-09-27 Monash University Method of identifying chromosomal abnormalities and prenatal diagnosis
US20040197832A1 (en) 2003-04-03 2004-10-07 Mor Research Applications Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
US20050181429A1 (en) * 2003-04-03 2005-08-18 Monaliza Medical Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
US20060024722A1 (en) 2004-07-30 2006-02-02 Mark Fischer-Colbrie Samples for detection of oncofetal fibronectin and uses thereof
US20070224597A1 (en) 2006-03-23 2007-09-27 Biocept, Inc. Isolating fetal trophoblasts
US20090286271A1 (en) 2006-05-31 2009-11-19 Karumanchi Ananth S Methods of Diagnosing and Treating Complications of Pregnancy
US20110183338A1 (en) 2008-01-30 2011-07-28 Novartis Vaccines And Diagnostics, Inc. Two stage enrichment of cell-free fetal dna in maternal plasma
EP2250497B1 (en) * 2008-02-18 2014-09-10 Genetic Technologies Limited Cell processing and/or enrichment methods
US9447467B2 (en) 2009-04-21 2016-09-20 Genetic Technologies Limited Methods for obtaining fetal genetic material
EP2909315B1 (en) 2012-10-19 2019-05-01 Wayne State University Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis

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Publication number Publication date
DK2909315T3 (da) 2019-06-03
CA2888746C (en) 2022-07-26
JP6421123B2 (ja) 2018-11-07
WO2014062995A1 (en) 2014-04-24
ES2729182T3 (es) 2019-10-30
IN2015DN03186A (enExample) 2015-10-02
JP2015533504A (ja) 2015-11-26
EP2909315B1 (en) 2019-05-01
AU2013331171B2 (en) 2019-05-30
US10344315B2 (en) 2019-07-09
CA2888746A1 (en) 2014-04-24
EP2909315A1 (en) 2015-08-26
AU2013331171A1 (en) 2015-05-28
EP2909315A4 (en) 2016-04-20
HK1214294A1 (en) 2016-07-22
US20150267240A1 (en) 2015-09-24

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