IN2015DN03186A - - Google Patents
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- Publication number
- IN2015DN03186A IN2015DN03186A IN3186DEN2015A IN2015DN03186A IN 2015DN03186 A IN2015DN03186 A IN 2015DN03186A IN 3186DEN2015 A IN3186DEN2015 A IN 3186DEN2015A IN 2015DN03186 A IN2015DN03186 A IN 2015DN03186A
- Authority
- IN
- India
- Prior art keywords
- cells
- fetal
- endocervical sample
- disassociated
- isolating
- Prior art date
Links
- 230000001605 fetal effect Effects 0.000 abstract 7
- 238000000034 method Methods 0.000 abstract 4
- 208000036818 High risk pregnancy Diseases 0.000 abstract 1
- 239000000090 biomarker Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000012252 genetic analysis Methods 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 230000008774 maternal effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000003097 mucus Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70539—MHC-molecules, e.g. HLA-molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Developmental Biology & Embryology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pregnancy & Childbirth (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261715854P | 2012-10-19 | 2012-10-19 | |
| PCT/US2013/065570 WO2014062995A1 (en) | 2012-10-19 | 2013-10-18 | Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2015DN03186A true IN2015DN03186A (enExample) | 2015-10-02 |
Family
ID=50488767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3186DEN2015 IN2015DN03186A (enExample) | 2012-10-19 | 2013-10-18 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10344315B2 (enExample) |
| EP (1) | EP2909315B1 (enExample) |
| JP (1) | JP6421123B2 (enExample) |
| AU (1) | AU2013331171B2 (enExample) |
| CA (1) | CA2888746C (enExample) |
| DK (1) | DK2909315T3 (enExample) |
| ES (1) | ES2729182T3 (enExample) |
| IN (1) | IN2015DN03186A (enExample) |
| TR (1) | TR201908019T4 (enExample) |
| WO (1) | WO2014062995A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2909315B1 (en) | 2012-10-19 | 2019-05-01 | Wayne State University | Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis |
| WO2016057993A1 (en) | 2014-10-10 | 2016-04-14 | Wayne State University | Methods and compositions relating to assays of fetal extravillous trophoblast cells |
| US10808239B2 (en) | 2016-04-06 | 2020-10-20 | Wayne State University | Isolation and analysis of fetal DNA from extravillous trophoblast cells retrieved from the endocervical canal |
| EP3442706B1 (en) | 2016-04-13 | 2025-07-23 | NextGen Jane, Inc. | Sample collection and preservation methods |
| WO2019021065A2 (en) * | 2017-02-13 | 2019-01-31 | Trophodiagnostics, Llc | NEW SYSTEM AND METHOD FOR COLLECTING, ENRICHING AND ISOLATING TROPHOBLASTIC CELLS FROM A ENDOCERVICAL CHANNEL |
| US11230729B2 (en) | 2018-04-20 | 2022-01-25 | Inanna Diagnostics, Inc | Methods and devices for obtaining cellular and DNA material from human female reproductive system |
| TWI668423B (zh) * | 2018-10-02 | 2019-08-11 | 吳宏偉 | 細胞分選方法及系統 |
| CN111122857A (zh) * | 2018-10-31 | 2020-05-08 | 苏州浚惠生物科技有限公司 | 胎儿滋养层细胞的标志物、鉴定方法、检测试剂盒和应用 |
| CN111304153A (zh) * | 2019-12-17 | 2020-06-19 | 广东凯普生物科技股份有限公司 | 一种分离滋养层细胞的方法 |
| JP7824649B2 (ja) * | 2020-02-21 | 2026-03-05 | 国立大学法人東海国立大学機構 | 胎児発育不全に対する定量的評価指標 |
| CN112980779B (zh) * | 2021-05-20 | 2021-08-24 | 广州凯普医药科技有限公司 | 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法 |
| AU2023406050A1 (en) * | 2022-11-29 | 2025-06-12 | Akna Health Inc. | Identification of cervical biomarkers |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629147A (en) | 1992-07-17 | 1997-05-13 | Aprogenex, Inc. | Enriching and identifying fetal cells in maternal blood for in situ hybridization |
| EP0587951B1 (en) | 1992-09-18 | 1997-12-17 | AMERSHAM INTERNATIONAL plc | Cell nuclei capture method and device used therefor |
| WO1999041613A1 (en) * | 1998-02-12 | 1999-08-19 | Immunivest | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| AUPR749901A0 (en) * | 2001-09-06 | 2001-09-27 | Monash University | Method of identifying chromosomal abnormalities and prenatal diagnosis |
| US20040197832A1 (en) * | 2003-04-03 | 2004-10-07 | Mor Research Applications Ltd. | Non-invasive prenatal genetic diagnosis using transcervical cells |
| US20050181429A1 (en) * | 2003-04-03 | 2005-08-18 | Monaliza Medical Ltd. | Non-invasive prenatal genetic diagnosis using transcervical cells |
| US20060024722A1 (en) | 2004-07-30 | 2006-02-02 | Mark Fischer-Colbrie | Samples for detection of oncofetal fibronectin and uses thereof |
| US20070224597A1 (en) * | 2006-03-23 | 2007-09-27 | Biocept, Inc. | Isolating fetal trophoblasts |
| US20090286271A1 (en) | 2006-05-31 | 2009-11-19 | Karumanchi Ananth S | Methods of Diagnosing and Treating Complications of Pregnancy |
| BRPI0906641A2 (pt) | 2008-01-30 | 2019-09-10 | Novartis Ag | enriquecimento de dois estágios de dna fetal livre de célula em plasma materno |
| US20110027795A1 (en) * | 2008-02-18 | 2011-02-03 | Genetic Technologies Limited | Cell processing and/or enrichment methods |
| AU2010239131A1 (en) * | 2009-04-21 | 2011-11-17 | Genetic Technologies Limited | Methods for obtaining fetal genetic material |
| EP2909315B1 (en) | 2012-10-19 | 2019-05-01 | Wayne State University | Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis |
-
2013
- 2013-10-18 EP EP13847056.2A patent/EP2909315B1/en active Active
- 2013-10-18 ES ES13847056T patent/ES2729182T3/es active Active
- 2013-10-18 WO PCT/US2013/065570 patent/WO2014062995A1/en not_active Ceased
- 2013-10-18 TR TR2019/08019T patent/TR201908019T4/tr unknown
- 2013-10-18 US US14/436,270 patent/US10344315B2/en active Active
- 2013-10-18 IN IN3186DEN2015 patent/IN2015DN03186A/en unknown
- 2013-10-18 AU AU2013331171A patent/AU2013331171B2/en active Active
- 2013-10-18 DK DK13847056.2T patent/DK2909315T3/da active
- 2013-10-18 JP JP2015538043A patent/JP6421123B2/ja active Active
- 2013-10-18 CA CA2888746A patent/CA2888746C/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10344315B2 (en) | 2019-07-09 |
| JP2015533504A (ja) | 2015-11-26 |
| AU2013331171B2 (en) | 2019-05-30 |
| EP2909315B1 (en) | 2019-05-01 |
| CA2888746A1 (en) | 2014-04-24 |
| EP2909315A1 (en) | 2015-08-26 |
| DK2909315T3 (da) | 2019-06-03 |
| TR201908019T4 (tr) | 2019-06-21 |
| ES2729182T3 (es) | 2019-10-30 |
| CA2888746C (en) | 2022-07-26 |
| US20150267240A1 (en) | 2015-09-24 |
| HK1214294A1 (en) | 2016-07-22 |
| AU2013331171A1 (en) | 2015-05-28 |
| JP6421123B2 (ja) | 2018-11-07 |
| EP2909315A4 (en) | 2016-04-20 |
| WO2014062995A1 (en) | 2014-04-24 |
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