TR201900260T4 - Bir rekombinant konakçı organizmada bir aspartik proteaz üretmeye yönelik gelişmiş yöntem. - Google Patents
Bir rekombinant konakçı organizmada bir aspartik proteaz üretmeye yönelik gelişmiş yöntem. Download PDFInfo
- Publication number
- TR201900260T4 TR201900260T4 TR2019/00260T TR201900260T TR201900260T4 TR 201900260 T4 TR201900260 T4 TR 201900260T4 TR 2019/00260 T TR2019/00260 T TR 2019/00260T TR 201900260 T TR201900260 T TR 201900260T TR 201900260 T4 TR201900260 T4 TR 201900260T4
- Authority
- TR
- Turkey
- Prior art keywords
- producing
- improved method
- aspartic protease
- recombinant host
- host organism
- Prior art date
Links
- 108091005502 Aspartic proteases Proteins 0.000 title abstract 2
- 102000035101 Aspartic proteases Human genes 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108090000746 Chymosin Proteins 0.000 abstract 1
- 229940080701 chymosin Drugs 0.000 abstract 1
- 230000013595 glycosylation Effects 0.000 abstract 1
- 238000006206 glycosylation reaction Methods 0.000 abstract 1
- GNOLWGAJQVLBSM-UHFFFAOYSA-N n,n,5,7-tetramethyl-1,2,3,4-tetrahydronaphthalen-1-amine Chemical compound C1=C(C)C=C2C(N(C)C)CCCC2=C1C GNOLWGAJQVLBSM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/02—Making cheese curd
- A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
- A23C19/0326—Rennet produced by fermentation, e.g. microbial rennet; Rennet produced by genetic engineering
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
En az bir -N-X-T- glikosilasyon bölgesi içermesi için modifiye edilen kimozin gibi bir aspartik proteaz içeren bir polipeptit ve söz konusu polipeptidi üretmeye yönelik bir yöntem.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200200922 | 2002-06-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201900260T4 true TR201900260T4 (tr) | 2019-02-21 |
Family
ID=29724351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2019/00260T TR201900260T4 (tr) | 2002-06-17 | 2003-06-16 | Bir rekombinant konakçı organizmada bir aspartik proteaz üretmeye yönelik gelişmiş yöntem. |
Country Status (7)
Country | Link |
---|---|
US (1) | US7776581B2 (tr) |
EP (1) | EP1515986B1 (tr) |
AU (1) | AU2003232180A1 (tr) |
DK (1) | DK1515986T3 (tr) |
ES (1) | ES2707384T3 (tr) |
TR (1) | TR201900260T4 (tr) |
WO (1) | WO2003106484A1 (tr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2387028T3 (es) * | 2003-12-31 | 2012-09-12 | Merck Patent Gmbh | Proteína de fusión de Fc-eritropoyetina con farmacocinética mejorada |
ATE527362T1 (de) * | 2004-03-25 | 2011-10-15 | Iogen Bio Products Corp | Verbesserte expression zeigendemodifizierte xylanasen |
US9493759B2 (en) | 2008-12-12 | 2016-11-15 | Novozymes, Inc. | Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same |
JP2016504920A (ja) * | 2013-02-05 | 2016-02-18 | セーホーエル.ハンセン アクティーゼルスカブ | 脱グリコシル化ステップを介したタンパク質の改善された精製 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0123928A3 (en) | 1983-03-31 | 1986-02-05 | Codon Genetic Engineering Laboratories | Recombinant dna coding for a polypeptide displaying milk clotting activity |
DK47493D0 (da) * | 1993-04-27 | 1993-04-27 | Novo Nordisk As | Fremgangsmaade til fremstilling af ost |
DE69535877D1 (de) * | 1994-12-21 | 2008-12-11 | Hansens Lab | Mikrobiell erzeugtes rennin mit verbesserter milchgerinnungsaktivität und verfahren zu dessen herstellung |
ATE400661T1 (de) * | 1999-08-23 | 2008-07-15 | Sembiosys Genetics Inc | Kommerzielle herstellung von chymosin in pflanzen |
EP1299535A2 (en) * | 2000-06-30 | 2003-04-09 | Maxygen Aps | Peptide extended glycosylated polypeptides |
GB0102903D0 (en) * | 2001-02-05 | 2001-03-21 | Inpharmatica Ltd | Novel protein |
AU2002358179A1 (en) * | 2001-12-21 | 2003-07-09 | Dsm Ip Assets B.V. | New rennets |
-
2003
- 2003-06-16 TR TR2019/00260T patent/TR201900260T4/tr unknown
- 2003-06-16 DK DK03759881.0T patent/DK1515986T3/da active
- 2003-06-16 ES ES03759881T patent/ES2707384T3/es not_active Expired - Lifetime
- 2003-06-16 US US10/518,414 patent/US7776581B2/en active Active
- 2003-06-16 EP EP03759881.0A patent/EP1515986B1/en not_active Expired - Lifetime
- 2003-06-16 AU AU2003232180A patent/AU2003232180A1/en not_active Abandoned
- 2003-06-16 WO PCT/DK2003/000398 patent/WO2003106484A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK1515986T3 (da) | 2019-01-02 |
ES2707384T3 (es) | 2019-04-03 |
US7776581B2 (en) | 2010-08-17 |
EP1515986B1 (en) | 2018-10-24 |
WO2003106484A1 (en) | 2003-12-24 |
EP1515986A1 (en) | 2005-03-23 |
AU2003232180A1 (en) | 2003-12-31 |
US20060099588A1 (en) | 2006-05-11 |
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