TR200402258T4 - Lipit keseleri üretmek için yöntem ve cihaz - Google Patents
Lipit keseleri üretmek için yöntem ve cihazInfo
- Publication number
- TR200402258T4 TR200402258T4 TR2004/02258T TR200402258T TR200402258T4 TR 200402258 T4 TR200402258 T4 TR 200402258T4 TR 2004/02258 T TR2004/02258 T TR 2004/02258T TR 200402258 T TR200402258 T TR 200402258T TR 200402258 T4 TR200402258 T4 TR 200402258T4
- Authority
- TR
- Turkey
- Prior art keywords
- lipid
- vesicles
- producing
- pouches
- liquids
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Steroid Compounds (AREA)
- Reciprocating Pumps (AREA)
Abstract
Lipit keseleri üretmek için yöntem ve bir tertibat olup, tertibat sunlari içerir:polar sivi fazi tasimak için bir boru (1), lipit içeren organik sivi fazi tasimak için bir boru (2), olusan lipit keselerinin toplanmasi için bir toplama kabi (7) ve sivi fazlarin borulardan (1) ve (2) iletimini saglan vasitalar. Boru (1) sivi geçirgen ortak bir açiklik (3) üzerinden boruya (2) baglanir. Ortak açiklik (3), borudaki (2) organik sivi faz açikliktan (3) geçip borudan (1) akan polar sivi faza esas itibariyle dik bir açiyla gelecek ve açikliktan (3) geçen polar sivi fazin içine tercihen püskürtme bugu biçiminde girecek sekilde düzenlenmistir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00123953A EP1203614A1 (de) | 2000-11-03 | 2000-11-03 | Verfahren und Vorrichtung zur Herstellung von Lipidvesikeln |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200402258T4 true TR200402258T4 (tr) | 2004-10-21 |
Family
ID=8170281
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2004/02258T TR200402258T4 (tr) | 2000-11-03 | 2001-10-31 | Lipit keseleri üretmek için yöntem ve cihaz |
Country Status (11)
Country | Link |
---|---|
US (1) | US6843942B2 (tr) |
EP (2) | EP1203614A1 (tr) |
AT (1) | ATE268638T1 (tr) |
AU (2) | AU1598702A (tr) |
CA (1) | CA2427640C (tr) |
DE (1) | DE50102554D1 (tr) |
DK (1) | DK1337322T3 (tr) |
ES (1) | ES2220829T3 (tr) |
PT (1) | PT1337322E (tr) |
TR (1) | TR200402258T4 (tr) |
WO (1) | WO2002036257A1 (tr) |
Families Citing this family (56)
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AU756196B2 (en) * | 1998-11-13 | 2003-01-09 | Optime Therapeutics, Inc. | Method and apparatus for liposome production |
US20040009126A1 (en) * | 2002-03-05 | 2004-01-15 | Transave, Inc. | Inhalation system for prevention and treatment of intracellular infections |
JP4722481B2 (ja) | 2002-06-28 | 2011-07-13 | プロティバ バイオセラピューティクス リミテッド | リポソーム製造方法および装置 |
US7879351B2 (en) * | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
ES2831305T3 (es) * | 2002-10-29 | 2021-06-08 | Insmed Inc | Liposomas que comprenden un aminoglucósido para el tratamiento de infecciones pulmonares |
CA2418498C (en) | 2003-02-05 | 2007-12-18 | Interwrap Inc. | Multilayer slip resistant sheet material |
US7470408B2 (en) | 2003-12-18 | 2008-12-30 | Velocys | In situ mixing in microchannels |
TWI395591B (zh) * | 2004-04-01 | 2013-05-11 | Oncothyreon Inc | 黏液性糖蛋白(muc-1)疫苗 |
AT500143A1 (de) * | 2004-04-22 | 2005-11-15 | Sanochemia Pharmazeutika Ag | Cholinesterase-inhibitoren in liposomen sowie deren herstellung und verwendung |
US8524274B2 (en) | 2004-10-18 | 2013-09-03 | Polymun Scientific Immunbiologische Forschung Gmbh | Liposomal composition comprising an active ingredient for relaxing smooth muscle, the production of this composition and the therapeutic use thereof |
JP5639338B2 (ja) * | 2005-07-27 | 2014-12-10 | プロチバ バイオセラピューティクス インコーポレイティッド | リポソームの製造システムおよび製造方法 |
DE102006054192A1 (de) * | 2006-03-17 | 2007-09-20 | Novosom Ag | Effizientes Verfahren zur Beladung von amphoteren Liposomen mit Nukleinsäure-Wirkstoffen |
US20120021042A1 (en) * | 2005-09-15 | 2012-01-26 | Steffen Panzner | Efficient Method For Loading Amphoteric Liposomes With Nucleic Acid Active Substances |
JP5324223B2 (ja) | 2005-12-08 | 2013-10-23 | トランセイブ, インク. | 肺感染症を治療する抗感染薬の脂質ベースの組成物及びその使用法 |
CA2633399C (en) | 2005-12-12 | 2016-01-26 | Ac Immune S.A. | Therapeutic vaccine |
WO2007073919A2 (en) | 2005-12-28 | 2007-07-05 | Nowicky Wassili | Method and kit for the detection of cancer |
DE102006015271A1 (de) * | 2006-04-01 | 2007-10-11 | Lohmann & Rauscher Gmbh & Co. Kg | Biguanidhaltige Liposomen |
JP5600432B2 (ja) * | 2006-04-06 | 2014-10-01 | インスメッド, インコーポレイテッド | コアセルベート化誘導リポソーム被包法及びその調合物 |
WO2008012062A1 (en) * | 2006-07-24 | 2008-01-31 | Polymun Scientific Immunbiologische Forschung Gmbh | Antigenic proteoliposomes and method of manufacture |
WO2008137717A1 (en) | 2007-05-04 | 2008-11-13 | Transave, Inc. | Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof |
US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
CN104672311A (zh) * | 2007-10-02 | 2015-06-03 | 玛瑞纳生物技术有限公司 | 用于递送核酸的脂肽 |
US7745667B2 (en) * | 2008-04-07 | 2010-06-29 | Velocys | Microchannel apparatus comprising structured walls, chemical processes, methods of making formaldehyde |
KR20110071017A (ko) | 2008-10-16 | 2011-06-27 | 마리나 바이오테크, 인크. | 유전자 침묵 치료제의 리포좀에 의한 효율적인 전달을 위한 프로세스 및 조성물 |
RU2573409C2 (ru) | 2009-11-04 | 2016-01-20 | Дзе Юниверсити Оф Бритиш Коламбиа | Содержащие нуклеиновые кислоты липидные частицы и относящиеся к ним способы |
WO2011120023A1 (en) | 2010-03-26 | 2011-09-29 | Marina Biotech, Inc. | Nucleic acid compounds for inhibiting survivin gene expression uses thereof |
EP2374535A1 (de) * | 2010-04-06 | 2011-10-12 | Bühler AG | Verfahren und Vorrichtungen zur Vesikelbildung, insbesondere unter Verwendung von Block-Coplymeren |
WO2011133584A2 (en) | 2010-04-19 | 2011-10-27 | Marina Biotech, Inc. | Nucleic acid compounds for inhibiting hras gene expression and uses thereof |
WO2011139843A2 (en) | 2010-04-28 | 2011-11-10 | Marina Biotech, Inc. | Multi-sirna compositions for reducing gene expression |
US20130315982A1 (en) | 2010-10-29 | 2013-11-28 | Mindinvest Holdings Ltd. | Liposomal drug composition containing a polymeric guanidine derivative |
EP2668201A2 (en) | 2011-01-28 | 2013-12-04 | Sanofi Pasteur SA | Immunological compositions comprising hiv gp41 polypeptide derivatives |
EP3069785A1 (en) | 2011-10-25 | 2016-09-21 | The University Of British Columbia | Limit size lipid nanoparticles and related methods |
US9579338B2 (en) | 2011-11-04 | 2017-02-28 | Nitto Denko Corporation | Method of producing lipid nanoparticles for drug delivery |
RU2647476C2 (ru) | 2011-11-04 | 2018-03-15 | Нитто Денко Корпорейшн | Способ получения липидных наночастиц для доставки лекарственного средства |
EP2601965A1 (en) | 2011-12-06 | 2013-06-12 | Apeiron Biologics AG | Compositions for preventing or treating adverse reactions of EGFR inhibition |
DE21212055T1 (de) | 2011-12-07 | 2022-08-04 | Alnylam Pharmaceuticals, Inc. | Biologisch abbaubare lipide zur freisetzung von wirkstoffen |
NZ700983A (en) | 2012-05-21 | 2016-10-28 | Insmed Inc | Systems for treating pulmonary infections |
CN103536533B (zh) * | 2012-07-17 | 2018-01-02 | 石药集团中奇制药技术(石家庄)有限公司 | 一种水溶性药物脂质体制备方法 |
WO2014048976A1 (en) | 2012-09-25 | 2014-04-03 | Vaxdyn Sl | Anti-acinetobacter baumannii immunogens |
EP2925298B1 (en) | 2012-11-29 | 2019-05-29 | Insmed Incorporated | Stabilized vancomycin formulations |
EP2971013B1 (en) | 2013-03-15 | 2020-08-19 | The University Of British Columbia | Lipid nanoparticles for transfection and related methods |
RS60827B1 (sr) | 2014-05-15 | 2020-10-30 | Insmed Inc | Postupci lečenja plućnih netuberkuloznih mikobakterijskih infekcija |
US10632072B2 (en) * | 2015-03-19 | 2020-04-28 | University Of Connecticut | Systems and methods for continuous manufacturing of liposomal drug formulations |
US20210284998A1 (en) | 2016-10-03 | 2021-09-16 | Precision Nanosystems Inc. | Compositions for Transfecting Resistant Cell Types |
JP2021513508A (ja) | 2018-02-12 | 2021-05-27 | インテアールエヌエー テクノロジーズ ビー.ヴイ.InteRNA Technologies B.V. | 抗がんマイクロrna及びその脂質製剤 |
US11571386B2 (en) | 2018-03-30 | 2023-02-07 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
RU2020135149A (ru) | 2018-04-06 | 2022-05-06 | Уцар Хелс ГМбХ | Лечение рака производными гуанидиния |
AU2019362031A1 (en) * | 2018-10-19 | 2021-04-08 | Translate Bio, Inc. | Pumpless encapsulation of messenger RNA |
EP3711749A1 (en) | 2019-03-19 | 2020-09-23 | Polymun Scientific Immunbiologische Forschung GmbH | Method of making lipid nanoparticles |
GB202011367D0 (en) | 2020-07-22 | 2020-09-02 | Micropore Tech Limited | Method of preparing liposomes |
GB2600468A (en) | 2020-10-30 | 2022-05-04 | Excivion Ltd | Adjuvant composition |
DE102020214601A1 (de) | 2020-11-19 | 2022-05-19 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein | Verfahren und Vorrichtung zur Herstellung einer Flüssigkeit enthaltend Liposomen und hergestellte Flüssigkeit |
EP4119220A1 (en) | 2021-07-16 | 2023-01-18 | Andreas Jahn | Device and method for the formation of organic nanoparticles |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4206197A (en) | 1975-11-26 | 1980-06-03 | The United States Of America As Represented By The Secretary Of The Navy | Chemical encapsulation and distribution |
AU598002B2 (en) | 1986-07-15 | 1990-06-14 | Cilag Ltd. | Method of preparing single bilayered liposomes |
US4895452A (en) * | 1988-03-03 | 1990-01-23 | Micro-Pak, Inc. | Method and apparatus for producing lipid vesicles |
US5000887A (en) * | 1988-05-17 | 1991-03-19 | Liposome Technology, Inc. | Preparation of uniform-size liposomes |
AU2588297A (en) | 1996-04-04 | 1997-10-29 | Ortho Pharmaceutical Corporation | Liposome-based topical vitamin d formulation |
AU756196B2 (en) * | 1998-11-13 | 2003-01-09 | Optime Therapeutics, Inc. | Method and apparatus for liposome production |
-
2000
- 2000-11-03 EP EP00123953A patent/EP1203614A1/de not_active Withdrawn
-
2001
- 2001-10-31 DK DK01992612T patent/DK1337322T3/da active
- 2001-10-31 EP EP01992612A patent/EP1337322B1/de not_active Expired - Lifetime
- 2001-10-31 WO PCT/EP2001/012595 patent/WO2002036257A1/de active Search and Examination
- 2001-10-31 TR TR2004/02258T patent/TR200402258T4/tr unknown
- 2001-10-31 AU AU1598702A patent/AU1598702A/xx active Pending
- 2001-10-31 AU AU2002215987A patent/AU2002215987B2/en not_active Expired
- 2001-10-31 PT PT01992612T patent/PT1337322E/pt unknown
- 2001-10-31 DE DE50102554T patent/DE50102554D1/de not_active Expired - Lifetime
- 2001-10-31 AT AT01992612T patent/ATE268638T1/de active
- 2001-10-31 ES ES01992612T patent/ES2220829T3/es not_active Expired - Lifetime
- 2001-10-31 US US10/415,414 patent/US6843942B2/en not_active Expired - Lifetime
- 2001-10-31 CA CA002427640A patent/CA2427640C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
PT1337322E (pt) | 2004-10-29 |
ATE268638T1 (de) | 2004-06-15 |
US6843942B2 (en) | 2005-01-18 |
WO2002036257A1 (de) | 2002-05-10 |
DK1337322T3 (da) | 2004-09-13 |
DE50102554D1 (de) | 2004-07-15 |
EP1337322B1 (de) | 2004-06-09 |
CA2427640C (en) | 2006-09-05 |
EP1203614A1 (de) | 2002-05-08 |
EP1337322A1 (de) | 2003-08-27 |
CA2427640A1 (en) | 2003-05-01 |
US20040032037A1 (en) | 2004-02-19 |
AU2002215987B2 (en) | 2006-04-27 |
ES2220829T3 (es) | 2004-12-16 |
AU1598702A (en) | 2002-05-15 |
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