TR200201252T2 - 15-Hidroksieikosatetraenoik asit ile ilişkili bileşikler ve bunların kullanım yöntemleri - Google Patents

15-Hidroksieikosatetraenoik asit ile ilişkili bileşikler ve bunların kullanım yöntemleri

Info

Publication number
TR200201252T2
TR200201252T2 TR2002/01252T TR200201252T TR200201252T2 TR 200201252 T2 TR200201252 T2 TR 200201252T2 TR 2002/01252 T TR2002/01252 T TR 2002/01252T TR 200201252 T TR200201252 T TR 200201252T TR 200201252 T2 TR200201252 T2 TR 200201252T2
Authority
TR
Turkey
Prior art keywords
methods
hydroxyiecosatetraenoic
acid
related compounds
compounds
Prior art date
Application number
TR2002/01252T
Other languages
English (en)
Inventor
R. Hellberg Mark
M. Yanni John
Graff Gustav
A. Gamache Daniel
G. Klimko Peter
Original Assignee
Alcon, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon, Inc. filed Critical Alcon, Inc.
Publication of TR200201252T2 publication Critical patent/TR200201252T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups

Abstract

Göz kurumasinin iyilestirilmesi için HETE türevleri ve bunlarin kullanim yöntemleri anlatilmistir.
TR2002/01252T 1999-11-09 2000-10-23 15-Hidroksieikosatetraenoik asit ile ilişkili bileşikler ve bunların kullanım yöntemleri TR200201252T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16437699P 1999-11-09 1999-11-09

Publications (1)

Publication Number Publication Date
TR200201252T2 true TR200201252T2 (tr) 2003-02-21

Family

ID=22594209

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/01252T TR200201252T2 (tr) 1999-11-09 2000-10-23 15-Hidroksieikosatetraenoik asit ile ilişkili bileşikler ve bunların kullanım yöntemleri

Country Status (20)

Country Link
US (1) US6353012B1 (tr)
EP (1) EP1228026B1 (tr)
JP (1) JP2003513947A (tr)
KR (1) KR20020050238A (tr)
CN (1) CN1387502A (tr)
AR (1) AR031681A1 (tr)
AT (1) ATE257143T1 (tr)
AU (1) AU773499B2 (tr)
BR (1) BR0015404A (tr)
CA (1) CA2386636A1 (tr)
DE (1) DE60007547T2 (tr)
DK (1) DK1228026T3 (tr)
ES (1) ES2208441T3 (tr)
HK (1) HK1045985B (tr)
MX (1) MXPA02004700A (tr)
PL (1) PL356102A1 (tr)
PT (1) PT1228026E (tr)
TR (1) TR200201252T2 (tr)
WO (1) WO2001034547A2 (tr)
ZA (1) ZA200202280B (tr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003030894A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
US20030109488A1 (en) * 2001-10-11 2003-06-12 Alcon, Inc. Methods for treating dry eye
WO2003105831A1 (en) * 2002-06-14 2003-12-24 Alcon, Inc. Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders
US20040002514A1 (en) * 2002-06-14 2004-01-01 Alcon, Inc. Topical use of hydroxyeicosatetraenoic acid compounds to treat psoriasis
JP2006502183A (ja) * 2002-09-20 2006-01-19 アルコン，インコーポレイテッド ドライアイ障害の処置のためのサイトカイン合成インヒビターの使用
KR20070090928A (ko) 2004-11-19 2007-09-06 마텍 바이오싸이언스스 코포레이션 장쇄 다가불포화 지방산으로부터의 옥시리핀, 및 이의 제조방법 및 사용 방법
US7893106B2 (en) 2004-11-19 2011-02-22 Martek Biosciences, Corporation Oxylipins from stearidonic acid and γ-linolenic acid and methods of making and using the same
US9416118B2 (en) 2011-06-10 2016-08-16 The Brigham And Women's Hospital, Inc. Docosahexaenoyl ethanolamides

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US3991759A (en) 1975-10-28 1976-11-16 Alza Corporation Method and therapeutic system for treating aqueous deficient dry eye
US4131651A (en) 1977-10-25 1978-12-26 Barnes-Hind Pharmaceuticals, Inc. Treatment of dry eye
US4409205A (en) 1979-03-05 1983-10-11 Cooper Laboratories, Inc. Ophthalmic solution
US4370325A (en) 1979-03-30 1983-01-25 Dermik Laboratories Pharmaceutical compositions and method of treatment
AU546872B2 (en) 1982-06-16 1985-09-26 Unilever Plc Skin treatment compositions containing a fatty acid or ester
US4421748A (en) 1982-07-13 1983-12-20 Trager Seymour F Artificial tear aid
GB8319073D0 (en) 1983-07-14 1983-08-17 Efamol Ltd Fatty acid compositions
US4868154A (en) 1986-02-19 1989-09-19 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with melanocyte stimulating hormones
US4753945A (en) 1986-02-19 1988-06-28 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with phosphodiesterase inhibitors
US4883658A (en) 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4744980A (en) 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US4804539A (en) 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
US4818537A (en) 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
US4966773A (en) 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
US4914088A (en) 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US5278151A (en) 1987-04-02 1994-01-11 Ocular Research Of Boston, Inc. Dry eye treatment solution
US4921644A (en) 1988-02-29 1990-05-01 Technology Unlimited, Inc. Mucin directed lipsome
US4906467A (en) 1988-03-24 1990-03-06 New York Medical College Novel, long-duration treatment for glaucoma
US4923700A (en) 1988-06-03 1990-05-08 Kaufman Herbert E Artificial tear suspension
US5064655A (en) 1989-02-24 1991-11-12 Liposome Technology, Inc. Liposome gel composition and method
US5075104A (en) 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
US5174988A (en) 1989-07-27 1992-12-29 Scientific Development & Research, Inc. Phospholipid delivery system
AU655919B2 (en) 1990-02-22 1995-01-19 Macnaught Pty Limited Artificial tears
US5041434A (en) 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
ZA912797B (en) 1990-05-29 1992-12-30 Boston Ocular Res Dry eye treatment process and solution
EP0459148B1 (en) 1990-05-29 1996-01-03 Ocular Research Of Boston Inc. Dry eye treatment composition
US5102670A (en) 1990-09-14 1992-04-07 Abraham Nader G Method for treating eye disorders by reducing 12(r)-hydroxyeicosatetraenoic acid and 12(r)-dihydroxyeicosatrienoic acid levels
DE69212850T2 (de) 1991-01-15 1997-03-06 Alcon Lab Inc Verwendung von Karrageenan in topischen ophthalmologischen Zusammensetzungen
ZA927277B (en) 1991-10-02 1993-05-19 Boston Ocular Res Dry eye treatment process and solution.
EP0546728A3 (en) 1991-12-13 1993-09-08 Alcon Laboratories Inc Physiological tear compositions and methods for their preparation
ES2139005T3 (es) 1992-04-21 2000-02-01 Schepens Eye Res Inst Terapia ocular con androgeno en el sindrome de sjogren.
US5290572A (en) 1992-08-06 1994-03-01 Deo Corporation Opthalmic composition for treating dry eye
US5358706A (en) 1992-09-30 1994-10-25 Union Carbide Chemicals & Plastics Technology Corporation Muco-adhesive polymers
US5455265A (en) 1993-02-11 1995-10-03 Allergan, Inc. Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors
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Also Published As

Publication number Publication date
BR0015404A (pt) 2002-06-25
AR031681A1 (es) 2003-10-01
CA2386636A1 (en) 2001-05-17
ES2208441T3 (es) 2004-06-16
WO2001034547A3 (en) 2002-01-24
ATE257143T1 (de) 2004-01-15
CN1387502A (zh) 2002-12-25
ZA200202280B (en) 2003-05-28
AU1913201A (en) 2001-06-06
EP1228026B1 (en) 2004-01-02
WO2001034547A2 (en) 2001-05-17
DK1228026T3 (da) 2004-04-05
PL356102A1 (en) 2004-06-14
DE60007547T2 (de) 2004-06-17
DE60007547D1 (de) 2004-02-05
KR20020050238A (ko) 2002-06-26
HK1045985A1 (en) 2002-12-20
HK1045985B (zh) 2004-04-23
EP1228026A2 (en) 2002-08-07
JP2003513947A (ja) 2003-04-15
US6353012B1 (en) 2002-03-05
MXPA02004700A (es) 2004-09-10
AU773499B2 (en) 2004-05-27
PT1228026E (pt) 2004-04-30

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