TR199903192T2 - Eritropoetin, de�i�tirilmi� hemoglobin i�eren farmasotik kombine m�stahzarlar. - Google Patents
Eritropoetin, de�i�tirilmi� hemoglobin i�eren farmasotik kombine m�stahzarlar.Info
- Publication number
- TR199903192T2 TR199903192T2 TR1999/03192T TR9903192T TR199903192T2 TR 199903192 T2 TR199903192 T2 TR 199903192T2 TR 1999/03192 T TR1999/03192 T TR 1999/03192T TR 9903192 T TR9903192 T TR 9903192T TR 199903192 T2 TR199903192 T2 TR 199903192T2
- Authority
- TR
- Turkey
- Prior art keywords
- preparations containing
- erythropoietin
- modified hemoglobin
- combined preparations
- containing erythropoietin
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 6
- 102000003951 Erythropoietin Human genes 0.000 title abstract 4
- 108090000394 Erythropoietin Proteins 0.000 title abstract 4
- 229940105423 erythropoietin Drugs 0.000 title abstract 4
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title abstract 4
- 102000001554 Hemoglobins Human genes 0.000 title 1
- 108010054147 Hemoglobins Proteins 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97110168A EP0885613A1 (de) | 1997-06-21 | 1997-06-21 | Verwendung von modifizierten Hämoglobinen zur Behandlung von Anämien und Kombinationspräparate umfassend Erythropoietin und modifiziertes Hämoglobin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199903192T2 true TR199903192T2 (xx) | 2000-05-22 |
Family
ID=8226937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1999/03192T TR199903192T2 (xx) | 1997-06-21 | 1998-06-03 | Eritropoetin, de�i�tirilmi� hemoglobin i�eren farmasotik kombine m�stahzarlar. |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US6440932B1 (https=) |
| EP (2) | EP0885613A1 (https=) |
| JP (3) | JP2002504913A (https=) |
| KR (1) | KR100519904B1 (https=) |
| CN (1) | CN1185010C (https=) |
| AT (1) | ATE272405T1 (https=) |
| AU (1) | AU743475B2 (https=) |
| BR (1) | BR9810267A (https=) |
| CA (1) | CA2294448C (https=) |
| DE (1) | DE59811768D1 (https=) |
| DK (1) | DK0996462T3 (https=) |
| ES (1) | ES2226151T3 (https=) |
| PT (1) | PT996462E (https=) |
| TR (1) | TR199903192T2 (https=) |
| WO (1) | WO1998058660A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT977582E (pt) * | 1997-03-18 | 2002-12-31 | Roche Diagnostics Gmbh | Preparacoes farmaceuticas associadas contendo eritropoietina e preparacoes de ferro |
| US7345019B1 (en) * | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
| PL219131B1 (pl) * | 2000-05-15 | 2015-03-31 | Hoffmann La Roche | Ciekła kompozycja farmaceutyczna, sposób jej wytwarzania oraz jej zastosowanie |
| CA2431964C (en) | 2000-12-20 | 2013-09-10 | F. Hoffmann-La Roche Ag | Conjugates of erythropoietin (pep) with polyethylene glycol (peg) |
| US7767643B2 (en) | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
| US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| DE10215315A1 (de) * | 2002-04-05 | 2003-11-20 | Aventis Behring Gmbh Intellect | Human-Transferrin zur Behandlung der Anaemia of Chronic Disease (ACD) und des funktionellen Eisenmangels |
| US7459435B2 (en) * | 2002-08-29 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
| US7459436B2 (en) * | 2002-11-22 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
| BRPI0414887A (pt) * | 2003-09-29 | 2006-12-12 | Warren Pharmaceuticals Inc E T | métodos de tratamento, prevenção, retardo do inìcio ou redução dos efeitos de citocinas pró-inflamatórias em um mamìfero e de tratamento, prevenção, retardo do inìcio de uma condição associada com um efeito de citocinas pró-inflamatórias em um mamìfero, e, composição farmacêutica |
| RU2273485C2 (ru) * | 2004-05-19 | 2006-04-10 | Виктор Николаевич Алейников | Железосодержащий препарат "феррал" |
| US7772182B2 (en) * | 2004-08-05 | 2010-08-10 | Alza Corporation | Stable suspension formulations of erythropoietin receptor agonists |
| PL2054074T3 (pl) | 2006-08-04 | 2015-03-31 | Prolong Pharmaceuticals Llc | Zmodyfikowana erytropoetyna |
| CL2008002053A1 (es) | 2007-07-17 | 2009-05-22 | Hoffmann La Roche | Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion. |
| CL2008002054A1 (es) * | 2007-07-17 | 2009-05-29 | Hoffmann La Roche | Metodo para la regeneracion de una columna de cromatografia de intercambio cationico despues de la elusion de eritropoyetina monopeguilada y metodo para obtener una eritropoyetina monopeguilada, incorporando el metodo de regeneracion de la columna de intercambio cationico. |
| PT3380487T (pt) | 2015-11-23 | 2020-10-29 | Bristol Myers Squibb Co | Sistemas de aditivos para utilização na peguilação de proteínas |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL77081A (en) | 1984-12-04 | 1999-10-28 | Genetics Inst | Dna sequence encoding human erythropoietin process for the preparation thereof and a pharmaceutical composition of human erythropoietin |
| US4826811A (en) * | 1986-06-20 | 1989-05-02 | Northfield Laboratories, Inc. | Acellular red blood cell substitute |
| NO881507D0 (no) * | 1987-04-10 | 1988-04-07 | Ortho Pharma Corp | Fremgangsmaate for forhoeyning av hematokritnivaaet til et normalt pattedyr. |
| JPH03112934A (ja) * | 1989-09-27 | 1991-05-14 | Mitsubishi Kasei Corp | 圧縮成型可能な粉体組成物 |
| US5631219A (en) * | 1994-03-08 | 1997-05-20 | Somatogen, Inc. | Method of stimulating hematopoiesis with hemoglobin |
| CA2180529A1 (en) * | 1994-11-17 | 1996-05-30 | John Blue | Hemoglobin therapy in hemodialysis |
| DE19535571A1 (de) | 1995-09-14 | 1997-03-20 | Boehringer Mannheim Gmbh | Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten |
| EP0939644B1 (en) * | 1996-08-27 | 2004-01-14 | Hemosol Inc. | Enhanced stimulation of erythropoiesis |
-
1997
- 1997-06-21 EP EP97110168A patent/EP0885613A1/de not_active Withdrawn
-
1998
- 1998-06-03 TR TR1999/03192T patent/TR199903192T2/xx unknown
- 1998-06-03 ES ES98930785T patent/ES2226151T3/es not_active Expired - Lifetime
- 1998-06-03 US US09/446,378 patent/US6440932B1/en not_active Expired - Lifetime
- 1998-06-03 CN CNB988064324A patent/CN1185010C/zh not_active Expired - Lifetime
- 1998-06-03 CA CA002294448A patent/CA2294448C/en not_active Expired - Lifetime
- 1998-06-03 BR BR9810267-2A patent/BR9810267A/pt not_active Application Discontinuation
- 1998-06-03 EP EP98930785A patent/EP0996462B1/de not_active Expired - Lifetime
- 1998-06-03 WO PCT/EP1998/003299 patent/WO1998058660A1/de not_active Ceased
- 1998-06-03 DE DE59811768T patent/DE59811768D1/de not_active Expired - Lifetime
- 1998-06-03 JP JP50365599A patent/JP2002504913A/ja not_active Withdrawn
- 1998-06-03 AU AU81098/98A patent/AU743475B2/en not_active Expired
- 1998-06-03 AT AT98930785T patent/ATE272405T1/de active
- 1998-06-03 PT PT98930785T patent/PT996462E/pt unknown
- 1998-06-03 KR KR10-1999-7012111A patent/KR100519904B1/ko not_active Expired - Fee Related
- 1998-06-03 DK DK98930785T patent/DK0996462T3/da active
-
2002
- 2002-05-08 US US10/140,682 patent/US20020160956A1/en not_active Abandoned
-
2005
- 2005-03-28 US US11/091,876 patent/US20050197281A1/en not_active Abandoned
-
2007
- 2007-04-23 JP JP2007113275A patent/JP2007246530A/ja not_active Withdrawn
-
2011
- 2011-07-08 JP JP2011151443A patent/JP5785008B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP5785008B2 (ja) | 2015-09-24 |
| EP0996462B1 (de) | 2004-08-04 |
| US6440932B1 (en) | 2002-08-27 |
| CN1185010C (zh) | 2005-01-19 |
| CN1261282A (zh) | 2000-07-26 |
| KR100519904B1 (ko) | 2005-10-10 |
| AU8109898A (en) | 1999-01-04 |
| AU743475B2 (en) | 2002-01-24 |
| JP2007246530A (ja) | 2007-09-27 |
| CA2294448C (en) | 2007-12-11 |
| ES2226151T3 (es) | 2005-03-16 |
| EP0996462A1 (de) | 2000-05-03 |
| DK0996462T3 (da) | 2004-11-29 |
| US20020160956A1 (en) | 2002-10-31 |
| WO1998058660A1 (de) | 1998-12-30 |
| KR20010014075A (ko) | 2001-02-26 |
| CA2294448A1 (en) | 1998-12-30 |
| PT996462E (pt) | 2004-12-31 |
| DE59811768D1 (de) | 2004-09-09 |
| EP0885613A1 (de) | 1998-12-23 |
| JP2011246474A (ja) | 2011-12-08 |
| US20050197281A1 (en) | 2005-09-08 |
| BR9810267A (pt) | 2000-09-12 |
| ATE272405T1 (de) | 2004-08-15 |
| JP2002504913A (ja) | 2002-02-12 |
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