TR199903001T2 - 2-{4-[4-(4,5-Dikloro-2-metilimidazol-1-YL) Butil]-1-piperazinil}-5-floropirimidin, hazirlanisi ve tedavi edici olarak kullanimi. - Google Patents

2-{4-[4-(4,5-Dikloro-2-metilimidazol-1-YL) Butil]-1-piperazinil}-5-floropirimidin, hazirlanisi ve tedavi edici olarak kullanimi.

Info

Publication number
TR199903001T2
TR199903001T2 TR1999/03001T TR9903001T TR199903001T2 TR 199903001 T2 TR199903001 T2 TR 199903001T2 TR 1999/03001 T TR1999/03001 T TR 1999/03001T TR 9903001 T TR9903001 T TR 9903001T TR 199903001 T2 TR199903001 T2 TR 199903001T2
Authority
TR
Turkey
Prior art keywords
fluoropyrimidine
piperazinyl
dichloro
butyl
methylimidazole
Prior art date
Application number
TR1999/03001T
Other languages
English (en)
Inventor
Merce-Vidal Ramon
Frigola-Constansa Jordi
Original Assignee
Laboratorios Del Dr. Esteve, S,A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Del Dr. Esteve, S,A. filed Critical Laboratorios Del Dr. Esteve, S,A.
Publication of TR199903001T2 publication Critical patent/TR199903001T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Abstract

Bulus, formül (I), 2-{4-[4-(4,5-Dikloro-2-metilimidazol-1-yl)- butil]-1-piperazinil}-5-floropirimidin bilesigi ve bunun fizyolojik olarak kabul edilebilen tuzlariyla ilgilidir.
TR1999/03001T 1997-06-02 1998-05-28 2-{4-[4-(4,5-Dikloro-2-metilimidazol-1-YL) Butil]-1-piperazinil}-5-floropirimidin, hazirlanisi ve tedavi edici olarak kullanimi. TR199903001T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9706738A FR2763950B1 (fr) 1997-06-02 1997-06-02 2- {4- [4-(4,5-dichloro-2-methylimidazol-1-yl)butyl] -1- piperazinyl }-5-fluoropyrimidine, sa preparation et son utilisation therapeutique

Publications (1)

Publication Number Publication Date
TR199903001T2 true TR199903001T2 (tr) 2000-07-21

Family

ID=9507480

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/03001T TR199903001T2 (tr) 1997-06-02 1998-05-28 2-{4-[4-(4,5-Dikloro-2-metilimidazol-1-YL) Butil]-1-piperazinil}-5-floropirimidin, hazirlanisi ve tedavi edici olarak kullanimi.

Country Status (22)

Country Link
US (2) US6303608B1 (tr)
EP (1) EP1007522B1 (tr)
JP (1) JP4344890B2 (tr)
KR (1) KR100556559B1 (tr)
CN (1) CN1094491C (tr)
AT (1) ATE228126T1 (tr)
AU (1) AU732722B2 (tr)
BR (1) BR9810240A (tr)
CA (1) CA2292746A1 (tr)
DE (1) DE69809564T2 (tr)
DK (1) DK1007522T3 (tr)
ES (1) ES2149691B1 (tr)
FR (1) FR2763950B1 (tr)
HU (1) HUP0002905A3 (tr)
IL (1) IL133216A0 (tr)
NO (1) NO318757B1 (tr)
NZ (1) NZ501566A (tr)
PL (1) PL190777B1 (tr)
PT (1) PT1007522E (tr)
RU (1) RU2191184C2 (tr)
TR (1) TR199903001T2 (tr)
WO (1) WO1998055476A1 (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101152658B1 (ko) * 2009-04-30 2012-06-18 한국과학기술연구원 세로토닌 5-ｈｔ6 길항 활성 효과를 갖는 피페라진 화합물 함유 조성물
RU2660583C1 (ru) * 2017-08-15 2018-07-06 Общество С Ограниченной Ответственностью "Валента - Интеллект" Применение буспирона для лечения функционального головокружения

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2642759B1 (fr) * 1989-02-09 1991-05-17 Laboratorios Esteve Sa Derives de pyrimidyl-piperazinyl-alkyl azoles avec activite anxiolytique et/ou tranquillisante
FR2672052B1 (fr) * 1991-01-28 1995-05-24 Esteve Labor Dr Derives d'aryl (ou heteroaryl)-piperazinyl-alkyl-azoles, leur preparation et leur application en tant que medicaments.
FR2673628B1 (fr) * 1991-03-07 1993-07-09 Esteve Labor Dr Procede de preparation de derives d'aryl (ou heteroaryl)-piperazinyl-butyl-azoles.
FR2712808B1 (fr) * 1993-11-25 1996-02-16 Esteve Labor Dr Utilisation des dérivés de 1-{4-[4-aryl(ou hétéroaryl)-1-pipérazinyl]-butyl}-1-H-azole pour la préparation de médicaments destinés au traitement des troubles de la sécrétion gastrique .
FR2742052B1 (fr) * 1995-12-12 1998-04-10 Esteve Labor Dr Utilisation des derives 1-(4-(4-aryl (ou heteroaryl)-1-piper azinyl)-buty)-1h-azole pour le traitement de la depression, des troubles obsessifs compulsifs, l'apnee du sommeil, les dysfonctions sexuelles, l'emese et le mal des transports

Also Published As

Publication number Publication date
EP1007522B1 (fr) 2002-11-20
DK1007522T3 (da) 2003-03-17
PT1007522E (pt) 2003-04-30
PL190777B1 (pl) 2006-01-31
NO995894L (no) 2000-02-01
KR100556559B1 (ko) 2006-03-06
ES2149691A1 (es) 2000-11-01
PL337113A1 (en) 2000-07-31
ATE228126T1 (de) 2002-12-15
JP2002501539A (ja) 2002-01-15
KR20010013274A (ko) 2001-02-26
CN1094491C (zh) 2002-11-20
NO995894D0 (no) 1999-12-01
EP1007522A1 (fr) 2000-06-14
NO318757B1 (no) 2005-05-02
FR2763950B1 (fr) 2002-09-20
RU2191184C2 (ru) 2002-10-20
AU7917098A (en) 1998-12-21
FR2763950A1 (fr) 1998-12-04
US6346620B1 (en) 2002-02-12
AU732722B2 (en) 2001-04-26
DE69809564T2 (de) 2003-07-10
HUP0002905A3 (en) 2002-01-28
US6303608B1 (en) 2001-10-16
NZ501566A (en) 2001-06-29
CA2292746A1 (fr) 1998-12-10
WO1998055476A1 (fr) 1998-12-10
JP4344890B2 (ja) 2009-10-14
DE69809564D1 (de) 2003-01-02
IL133216A0 (en) 2001-03-19
BR9810240A (pt) 2000-09-05
CN1261888A (zh) 2000-08-02
ES2149691B1 (es) 2001-05-16
HUP0002905A2 (hu) 2001-06-28

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