TN2018000341A1 - ANTl-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF. - Google Patents

ANTl-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF.

Info

Publication number
TN2018000341A1
TN2018000341A1 TNP/2018/000341A TN2018000341A TN2018000341A1 TN 2018000341 A1 TN2018000341 A1 TN 2018000341A1 TN 2018000341 A TN2018000341 A TN 2018000341A TN 2018000341 A1 TN2018000341 A1 TN 2018000341A1
Authority
TN
Tunisia
Prior art keywords
antibodies
complément
des
anticorps
complement factor
Prior art date
Application number
TNP/2018/000341A
Other languages
English (en)
Inventor
Tony Sangyoung Byun
Karen Sue Christopherson
Sandip Panicker
Graham Parry
Original Assignee
Bioverativ Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioverativ Usa Inc filed Critical Bioverativ Usa Inc
Publication of TN2018000341A1 publication Critical patent/TN2018000341A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TNP/2018/000341A 2016-04-04 2017-04-03 ANTl-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF. TN2018000341A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662317897P 2016-04-04 2016-04-04
PCT/US2017/025784 WO2017176651A1 (en) 2016-04-04 2017-04-03 Anti-complement factor bb antibodies and uses thereof

Publications (1)

Publication Number Publication Date
TN2018000341A1 true TN2018000341A1 (en) 2020-06-15

Family

ID=60000646

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP/2018/000341A TN2018000341A1 (en) 2016-04-04 2017-04-03 ANTl-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF.

Country Status (23)

Country Link
US (3) US10934347B2 (OSRAM)
EP (1) EP3452510A4 (OSRAM)
JP (3) JP6967528B2 (OSRAM)
KR (2) KR20240096672A (OSRAM)
CN (2) CN109563158B (OSRAM)
AU (2) AU2017246794B2 (OSRAM)
BR (1) BR112018070357A2 (OSRAM)
CA (1) CA3019332A1 (OSRAM)
CL (1) CL2018002810A1 (OSRAM)
CO (1) CO2018010827A2 (OSRAM)
CR (1) CR20180529A (OSRAM)
DO (1) DOP2018000219A (OSRAM)
EA (1) EA201892225A1 (OSRAM)
EC (1) ECSP18082302A (OSRAM)
IL (3) IL311675A (OSRAM)
MA (1) MA44878A (OSRAM)
MX (2) MX2018012176A (OSRAM)
MY (1) MY194603A (OSRAM)
PE (1) PE20190209A1 (OSRAM)
PH (1) PH12018502137A1 (OSRAM)
SG (1) SG11201808525UA (OSRAM)
TN (1) TN2018000341A1 (OSRAM)
WO (1) WO2017176651A1 (OSRAM)

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EP2598533B1 (en) 2010-07-28 2019-02-20 Gliknik Inc. Fusion proteins of natural human protein fragments to create orderly multimerized immunoglobulin fc compositions
AU2016297862C1 (en) 2015-07-24 2022-12-15 Gliknik Inc. Fusion proteins of human protein fragments to create orderly multimerized immunoglobulin Fc compositions with enhanced complement binding
TN2018000341A1 (en) 2016-04-04 2020-06-15 Bioverativ Usa Inc ANTl-COMPLEMENT FACTOR BB ANTIBODIES AND USES THEREOF.
PE20191354A1 (es) 2016-12-09 2019-10-01 Gliknik Inc Optimizacion de fabricacion de gl-2045, un stradomer multimerizante
KR20190093186A (ko) * 2016-12-09 2019-08-08 글리크닉 인코포레이티드 다가 Fc 화합물에 의해 염증성 장애를 치료하는 방법
EP3570894A4 (en) * 2017-01-17 2021-04-07 The Texas A&M University System ENDOLYSOSOMAL TARGETING CONJUGATES FOR BETTER LOAD MOLECULES DISTRIBUTION TO ENDOLYSOSOMAL COMPARTMENT OF TARGET CELLS
EP3694874A1 (en) 2017-10-11 2020-08-19 Bioverativ USA Inc. Methods of inducing complement activity
JP7403165B2 (ja) 2017-12-19 2023-12-22 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル 血液脳関門を通過してウイルスベクターを送達するための方法および組成物
CA3142840A1 (en) * 2019-06-27 2020-12-30 Verseau Therapeutics, Inc. Anti-cd53 compositions and methods for modulating myeloid cell inflammatory phenotypes and uses thereof
CA3147638A1 (en) * 2019-07-17 2021-01-21 Gemini Therapeutics Sub, Inc. Factor h potentiating antibodies and uses thereof
WO2021167949A1 (en) * 2020-02-18 2021-08-26 Children's Hospital Medical Center Compositions and methods for treating liver disease
KR20230004686A (ko) 2020-04-20 2023-01-06 젠자임 코포레이션 인간화 항-보체 인자 Bb 항체 및 그의 용도
JP7787164B2 (ja) 2020-09-23 2025-12-16 アキリオン ファーマシューティカルズ, インコーポレーテッド 補体媒介性障害の治療のための医薬化合物

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Also Published As

Publication number Publication date
CO2018010827A2 (es) 2018-11-22
PE20190209A1 (es) 2019-02-07
PH12018502137A1 (en) 2019-09-23
CN109563158B (zh) 2022-08-09
CA3019332A1 (en) 2017-10-12
JP2023139289A (ja) 2023-10-03
KR20240096672A (ko) 2024-06-26
EP3452510A4 (en) 2020-01-15
JP2021191789A (ja) 2021-12-16
US20240228599A1 (en) 2024-07-11
EA201892225A1 (ru) 2019-09-30
ECSP18082302A (es) 2019-01-31
WO2017176651A1 (en) 2017-10-12
SG11201808525UA (en) 2018-10-30
IL295288B2 (en) 2024-08-01
CL2018002810A1 (es) 2019-03-15
KR102673420B1 (ko) 2024-06-07
US11851482B2 (en) 2023-12-26
IL262010A (en) 2018-10-31
US20210221877A1 (en) 2021-07-22
NZ747018A (en) 2025-05-02
AU2024224000A1 (en) 2024-12-19
MX2023007149A (es) 2023-06-28
KR20190003951A (ko) 2019-01-10
CN109563158A (zh) 2019-04-02
EP3452510A1 (en) 2019-03-13
BR112018070357A2 (pt) 2019-01-29
JP2019513726A (ja) 2019-05-30
US10934347B2 (en) 2021-03-02
MA44878A (fr) 2019-03-13
AU2017246794B2 (en) 2024-07-04
AU2017246794A1 (en) 2018-10-25
CN116790614A (zh) 2023-09-22
MX2018012176A (es) 2019-02-07
DOP2018000219A (es) 2019-03-31
US20190153079A1 (en) 2019-05-23
MY194603A (en) 2022-12-06
IL311675A (en) 2024-05-01
JP6967528B2 (ja) 2021-11-17
IL295288B1 (en) 2024-04-01
JP7326393B2 (ja) 2023-08-15
CR20180529A (es) 2019-03-21
IL295288A (en) 2022-10-01
IL262010B (en) 2022-09-01

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