TN2010000467A1 - Cyclic inhibitors of 11 beta hydroxysterioid dehydrogenase 1 - Google Patents
Cyclic inhibitors of 11 beta hydroxysterioid dehydrogenase 1Info
- Publication number
- TN2010000467A1 TN2010000467A1 TNP2010000467A TN2010000467A TN2010000467A1 TN 2010000467 A1 TN2010000467 A1 TN 2010000467A1 TN P2010000467 A TNP2010000467 A TN P2010000467A TN 2010000467 A TN2010000467 A TN 2010000467A TN 2010000467 A1 TN2010000467 A1 TN 2010000467A1
- Authority
- TN
- Tunisia
- Prior art keywords
- hydroxysterioid
- dehydrogenase
- beta
- cyclic inhibitors
- cortisol
- Prior art date
Links
- 101710088194 Dehydrogenase Proteins 0.000 title 1
- 125000004122 cyclic group Chemical group 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229960000890 hydrocortisone Drugs 0.000 abstract 2
- 230000005764 inhibitory process Effects 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- FUFLCEKSBBHCMO-UHFFFAOYSA-N 11-dehydrocorticosterone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 FUFLCEKSBBHCMO-UHFFFAOYSA-N 0.000 abstract 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 abstract 1
- MFYSYFVPBJMHGN-UHFFFAOYSA-N Cortisone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)(O)C(=O)CO)C4C3CCC2=C1 MFYSYFVPBJMHGN-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229960004544 cortisone Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2009/002653 WO2009134400A1 (en) | 2008-05-01 | 2009-04-30 | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2010000467A1 true TN2010000467A1 (en) | 2012-05-24 |
Family
ID=45478607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2010000467A TN2010000467A1 (en) | 2009-04-30 | 2010-10-14 | Cyclic inhibitors of 11 beta hydroxysterioid dehydrogenase 1 |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JP5784006B2 (enExample) |
| AP (1) | AP2011005948A0 (enExample) |
| CL (1) | CL2014001815A1 (enExample) |
| CO (1) | CO6501139A2 (enExample) |
| IL (1) | IL215249A (enExample) |
| MX (1) | MX2011011503A (enExample) |
| NZ (1) | NZ595473A (enExample) |
| PE (1) | PE20120794A1 (enExample) |
| TN (1) | TN2010000467A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5679997B2 (ja) * | 2009-02-04 | 2015-03-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5451611B2 (ja) * | 2007-07-26 | 2014-03-26 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター |
-
2010
- 2010-04-30 NZ NZ595473A patent/NZ595473A/en not_active IP Right Cessation
- 2010-04-30 JP JP2012508772A patent/JP5784006B2/ja active Active
- 2010-04-30 AP AP2011005948A patent/AP2011005948A0/xx unknown
- 2010-04-30 PE PE2011001866A patent/PE20120794A1/es not_active Application Discontinuation
- 2010-04-30 MX MX2011011503A patent/MX2011011503A/es active IP Right Grant
- 2010-10-14 TN TNP2010000467A patent/TN2010000467A1/fr unknown
-
2011
- 2011-09-20 IL IL215249A patent/IL215249A/en not_active IP Right Cessation
- 2011-10-05 CO CO11131281A patent/CO6501139A2/es not_active Application Discontinuation
-
2014
- 2014-07-08 CL CL2014001815A patent/CL2014001815A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PE20120794A1 (es) | 2012-07-26 |
| IL215249A0 (en) | 2011-12-29 |
| IL215249A (en) | 2014-12-31 |
| NZ595473A (en) | 2014-01-31 |
| AP2011005948A0 (en) | 2011-10-31 |
| JP5784006B2 (ja) | 2015-09-24 |
| HK1169409A1 (en) | 2013-01-25 |
| CL2014001815A1 (es) | 2015-02-13 |
| MX2011011503A (es) | 2011-11-18 |
| CO6501139A2 (es) | 2012-08-15 |
| JP2012525440A (ja) | 2012-10-22 |
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