SV2009002861A - Compuestos de pirimidina amida como inhibidores de pgds - Google Patents

Compuestos de pirimidina amida como inhibidores de pgds

Info

Publication number
SV2009002861A
SV2009002861A SV2008002861A SV2008002861A SV2009002861A SV 2009002861 A SV2009002861 A SV 2009002861A SV 2008002861 A SV2008002861 A SV 2008002861A SV 2008002861 A SV2008002861 A SV 2008002861A SV 2009002861 A SV2009002861 A SV 2009002861A
Authority
SV
El Salvador
Prior art keywords
amida
pyrimidine compounds
pgds inhibitors
depression
therapy
Prior art date
Application number
SV2008002861A
Other languages
English (en)
Inventor
Suzanne C Aldous
John Ziqi Jiang
Jinqi Lu
Liang Ma
Lan Mu
Harry Randall Munson
Jeffrey Stephen Sabol
Sukanthini Thurairatnam
Christopher Loren Vandeusen
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38007055&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SV2009002861(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of SV2009002861A publication Critical patent/SV2009002861A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)

Abstract

ESTA INVENCIÓN SE REFIERE A UN COMPUESTO DE FÓRMULA (I): (VER FORMULA); EN LA QUE R1, R2, R3 Y L1 SON COMO SE HAN DEFINIDO ANTERIORMENTE, UNA COMPOSICIÓN FARMACÉUTICA QUE COMPRENDE EL COMPUESTO, Y EL USO DEL COMPUESTO PARA TRATAR TRASTORNOS ALÉRGICOS Y/O INFLAMATORIOS, PARTICULARMENTE TRASTORNOS TALES COMO RINITIS ALÉRGICA, ASMA Y/O ENFERMEDAD PULMONAR OBSTRUCTIVA CRÓNICA (COPD)
SV2008002861A 2005-12-19 2008-04-04 Compuestos de pirimidina amida como inhibidores de pgds SV2009002861A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75173005P 2005-12-19 2005-12-19
US11/612,249 US20070155827A1 (en) 2005-12-19 2006-12-18 Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression

Publications (1)

Publication Number Publication Date
SV2009002861A true SV2009002861A (es) 2009-02-23

Family

ID=38007055

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2008002861A SV2009002861A (es) 2005-12-19 2008-04-04 Compuestos de pirimidina amida como inhibidores de pgds

Country Status (26)

Country Link
US (1) US20070155827A1 (es)
EP (1) EP1973539B1 (es)
JP (1) JP5190376B2 (es)
KR (1) KR101415532B1 (es)
CN (1) CN101336106B (es)
AT (1) ATE464895T1 (es)
AU (1) AU2006331733B2 (es)
BR (1) BRPI0620014A2 (es)
CA (1) CA2634112C (es)
CR (1) CR10165A (es)
CY (1) CY1110669T1 (es)
DE (1) DE602006013883D1 (es)
DK (1) DK1973539T3 (es)
EA (1) EA015392B1 (es)
ES (1) ES2342846T3 (es)
HK (1) HK1125040A1 (es)
IL (1) IL192103A (es)
MY (1) MY148459A (es)
NI (1) NI200800176A (es)
NO (1) NO20083036L (es)
NZ (1) NZ569045A (es)
PL (1) PL1973539T3 (es)
PT (1) PT1973539E (es)
SI (1) SI1973539T1 (es)
SV (1) SV2009002861A (es)
WO (1) WO2007075751A1 (es)

Families Citing this family (16)

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MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
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US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
TW200812573A (en) 2006-05-19 2008-03-16 Janssen Pharmaceutica Nv Co-therapy for the treatment of epilepsy and related disorders
US20090247617A1 (en) * 2008-03-26 2009-10-01 Abdel-Magid Ahmed F Process for the preparation of benzo-fused heteroaryl sulfamates
US20090247616A1 (en) * 2008-03-26 2009-10-01 Smith-Swintosky Virginia L Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety
EA019544B1 (ru) * 2008-03-26 2014-04-30 Янссен Фармацевтика Н.В. Применение гетероциклических бензопроизводных сульфамида для лечения тревожных расстройств
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WO2009133109A1 (en) * 2008-04-29 2009-11-05 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Modulators of dopamine neurotransmission
BRPI0915890A2 (pt) * 2008-06-23 2015-11-03 Janssen Pharmaceutica Nv forma cristalina de (2s)-(-)-n-(6-cloro-2,3-di-hidro-benzo[1,4]dioxin-2-ilmetil)-sulfamida
US8815939B2 (en) * 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
EP2760852A1 (en) 2011-09-29 2014-08-06 Janssen Pharmaceutica, N.V. Improved process for the preparation of sulfamide derivatives
AU2012316279A1 (en) 2011-09-29 2014-04-17 Janssen Pharmaceutica Nv Process for the preparation of sulfamide derivatives

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Also Published As

Publication number Publication date
CN101336106B (zh) 2012-09-05
PL1973539T3 (pl) 2010-09-30
BRPI0620014A2 (pt) 2011-10-25
DK1973539T3 (da) 2010-08-02
PT1973539E (pt) 2010-05-25
CA2634112C (en) 2014-08-05
ES2342846T3 (es) 2010-07-15
AU2006331733A1 (en) 2007-07-05
US20070155827A1 (en) 2007-07-05
MY148459A (en) 2013-04-30
NO20083036L (no) 2008-09-05
EA015392B1 (ru) 2011-08-30
HK1125040A1 (en) 2009-07-31
WO2007075751A1 (en) 2007-07-05
NI200800176A (es) 2012-05-28
AU2006331733B2 (en) 2013-01-10
NZ569045A (en) 2011-05-27
CY1110669T1 (el) 2015-06-10
CN101336106A (zh) 2008-12-31
KR101415532B1 (ko) 2014-07-04
JP2009520034A (ja) 2009-05-21
JP5190376B2 (ja) 2013-04-24
IL192103A0 (en) 2009-08-03
DE602006013883D1 (de) 2010-06-02
EP1973539B1 (en) 2010-04-21
SI1973539T1 (sl) 2010-08-31
EA200870090A1 (ru) 2008-12-30
CA2634112A1 (en) 2007-07-05
EP1973539A1 (en) 2008-10-01
KR20080089414A (ko) 2008-10-06
IL192103A (en) 2012-10-31
ATE464895T1 (de) 2010-05-15
CR10165A (es) 2009-01-14

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