SU60211A1 - The method of obtaining aspirin - Google Patents
The method of obtaining aspirinInfo
- Publication number
- SU60211A1 SU60211A1 SU189560A SU189560A SU60211A1 SU 60211 A1 SU60211 A1 SU 60211A1 SU 189560 A SU189560 A SU 189560A SU 189560 A SU189560 A SU 189560A SU 60211 A1 SU60211 A1 SU 60211A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- aspirin
- obtaining
- acid
- anhydride
- catalyst
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
Ацетилирование салициловой кислоты можно Провадить в присутствии катайизаторов, например, серной кислоты, смеси третичных аминов и т. п.Acetylation of salicylic acid can be performed in the presence of cataizators, for example, sulfuric acid, mixtures of tertiary amines, etc.
Авторы насто щего изобретени предлагают при проведен ии этой реакции примен ть в качестве катализатора фталевый ангидрид.The inventors of the present invention suggest using phthalic anhydride as the catalyst for this reaction.
Процесс проводитс в отсутствии растворителей и при. небольшом (3%) избытке ускусвого ангидрида .The process is carried out in the absence of solvents and at. a small (3%) excess of accelerated anhydride.
Прйм-ер. Смесь 100 г салицилозой кислоты, 76 г 100%-го уксусного « 0,75 г фталевото аегидридов нагревают 3 часа, при 94°. Реакционную массу медленно охлаждаютPrym-er. A mixture of 100 g of salicylose acid, 76 g of 100% acetic acid, 0.75 g of phthaloic ahydride is heated for 3 hours at 94 °. The reaction mass is slowly cooled.
до 65°, вливают в нее маточник от предыдущей операции и подвергают кристаллизации. Выпавшие кристаллы аспирина отсасывают « промывают неболь1шим количеством уксусной кислоты. Выход 117 г.to 65 °, the mother liquor is poured into it from the previous operation and crystallized. The precipitated aspirin crystals are aspirated “washed with a small amount of acetic acid. Exit 117 g
Предмет изобретени .The subject matter of the invention.
Способ получени аспирина путем; нагреваИи салициловой кислоты с уксусным ангидридом в присутствии катализаторов, отличающ и и с тем, что в качестве катализатора примен ют фталевый ангидрид .The method of producing aspirin by; heating salicylic acid with acetic anhydride in the presence of catalysts, distinguished by the fact that phthalic anhydride is used as a catalyst.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU189560A SU60211A1 (en) | 1936-03-19 | 1936-03-19 | The method of obtaining aspirin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU189560A SU60211A1 (en) | 1936-03-19 | 1936-03-19 | The method of obtaining aspirin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU60211A1 true SU60211A1 (en) | 1940-11-30 |
Family
ID=48242140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU189560A SU60211A1 (en) | 1936-03-19 | 1936-03-19 | The method of obtaining aspirin |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU60211A1 (en) |
-
1936
- 1936-03-19 SU SU189560A patent/SU60211A1/en active
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