SU569282A3 - Способ получени -ацильных производных дезаланилтетаина - Google Patents
Способ получени -ацильных производных дезаланилтетаинаInfo
- Publication number
- SU569282A3 SU569282A3 SU7402048486A SU2048486A SU569282A3 SU 569282 A3 SU569282 A3 SU 569282A3 SU 7402048486 A SU7402048486 A SU 7402048486A SU 2048486 A SU2048486 A SU 2048486A SU 569282 A3 SU569282 A3 SU 569282A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- thetaine
- under reduced
- reduced pressure
- added
- solution
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 3
- 238000002360 preparation method Methods 0.000 title claims 2
- 239000000243 solution Substances 0.000 claims 5
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims 4
- 238000006243 chemical reaction Methods 0.000 claims 4
- 239000000047 product Substances 0.000 claims 4
- 238000003756 stirring Methods 0.000 claims 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims 3
- 229940024606 amino acid Drugs 0.000 claims 3
- 235000001014 amino acid Nutrition 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 2
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims 2
- 239000007853 buffer solution Substances 0.000 claims 2
- -1 carboxyl anhydride Chemical class 0.000 claims 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N methanol Natural products OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 2
- 239000011541 reaction mixture Substances 0.000 claims 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims 2
- VIRHVJKBDQINKD-YOEHRIQHSA-N (2S)-2-[[(2S)-2-[(2-benzamidoacetyl)amino]-3-phenylpropanoyl]amino]propanoic acid Chemical compound C(C1=CC=CC=C1)(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)O VIRHVJKBDQINKD-YOEHRIQHSA-N 0.000 claims 1
- YOETUEMZNOLGDB-UHFFFAOYSA-N 2-methylpropyl carbonochloridate Chemical compound CC(C)COC(Cl)=O YOETUEMZNOLGDB-UHFFFAOYSA-N 0.000 claims 1
- ZVNPWFOVUDMGRP-UHFFFAOYSA-N 4-methylaminophenol sulfate Chemical compound OS(O)(=O)=O.CNC1=CC=C(O)C=C1.CNC1=CC=C(O)C=C1 ZVNPWFOVUDMGRP-UHFFFAOYSA-N 0.000 claims 1
- XFOUAXMJRHNTOP-UHFFFAOYSA-N Bacilysin Natural products CC(N)C(=O)NC(C(O)=O)CC1CCC(=O)C2OC12 XFOUAXMJRHNTOP-UHFFFAOYSA-N 0.000 claims 1
- 241000207199 Citrus Species 0.000 claims 1
- 235000010469 Glycine max Nutrition 0.000 claims 1
- 244000068988 Glycine max Species 0.000 claims 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 1
- 101150003481 UNG1 gene Proteins 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 150000008064 anhydrides Chemical class 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- XEKAUTDWPYQNFU-UHFFFAOYSA-N chlorane Chemical compound Cl.Cl.Cl XEKAUTDWPYQNFU-UHFFFAOYSA-N 0.000 claims 1
- SIHHLZPXQLFPMC-UHFFFAOYSA-N chloroform;methanol;hydrate Chemical compound O.OC.ClC(Cl)Cl SIHHLZPXQLFPMC-UHFFFAOYSA-N 0.000 claims 1
- 229930002875 chlorophyll Natural products 0.000 claims 1
- 235000019804 chlorophyll Nutrition 0.000 claims 1
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 claims 1
- ZCDOYSPFYFSLEW-UHFFFAOYSA-N chromate(2-) Chemical compound [O-][Cr]([O-])(=O)=O ZCDOYSPFYFSLEW-UHFFFAOYSA-N 0.000 claims 1
- 235000020971 citrus fruits Nutrition 0.000 claims 1
- 239000003245 coal Substances 0.000 claims 1
- 238000004440 column chromatography Methods 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000003795 desorption Methods 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 150000004678 hydrides Chemical class 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 229910052907 leucite Inorganic materials 0.000 claims 1
- 230000003211 malignant effect Effects 0.000 claims 1
- 108091028606 miR-1 stem-loop Proteins 0.000 claims 1
- 229910052759 nickel Inorganic materials 0.000 claims 1
- 238000004816 paper chromatography Methods 0.000 claims 1
- 229960005190 phenylalanine Drugs 0.000 claims 1
- 125000000405 phenylalanyl group Chemical group 0.000 claims 1
- 239000008363 phosphate buffer Substances 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 239000000741 silica gel Substances 0.000 claims 1
- 229910002027 silica gel Inorganic materials 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000010409 thin film Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL1973164318A PL87546B1 (enrdf_load_stackoverflow) | 1973-07-26 | 1973-07-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU569282A3 true SU569282A3 (ru) | 1977-08-15 |
Family
ID=19963606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU7402048486A SU569282A3 (ru) | 1973-07-26 | 1974-07-25 | Способ получени -ацильных производных дезаланилтетаина |
Country Status (13)
-
1973
- 1973-07-26 PL PL1973164318A patent/PL87546B1/pl unknown
-
1974
- 1974-07-17 BE BE146631A patent/BE817735A/xx not_active IP Right Cessation
- 1974-07-18 IN IN1604/CAL/74A patent/IN140064B/en unknown
- 1974-07-19 CA CA205,149A patent/CA1034567A/en not_active Expired
- 1974-07-22 SE SE7409506A patent/SE434158B/xx unknown
- 1974-07-22 GB GB32334/74A patent/GB1481881A/en not_active Expired
- 1974-07-24 FR FR7425679A patent/FR2245669B1/fr not_active Expired
- 1974-07-24 CH CH1022674A patent/CH602688A5/xx not_active IP Right Cessation
- 1974-07-24 HU HU74PO573A patent/HU174054B/hu unknown
- 1974-07-24 DE DE2435619A patent/DE2435619A1/de active Granted
- 1974-07-25 JP JP8556474A patent/JPS5652896B2/ja not_active Expired
- 1974-07-25 SU SU7402048486A patent/SU569282A3/ru active
- 1974-07-26 NL NL7410104.A patent/NL159989C/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5652896B2 (enrdf_load_stackoverflow) | 1981-12-15 |
| CH602688A5 (enrdf_load_stackoverflow) | 1978-07-31 |
| DE2435619B2 (enrdf_load_stackoverflow) | 1979-05-10 |
| NL7410104A (nl) | 1975-01-28 |
| FR2245669A1 (enrdf_load_stackoverflow) | 1975-04-25 |
| NL159989C (nl) | 1979-09-17 |
| NL159989B (nl) | 1979-04-17 |
| CA1034567A (en) | 1978-07-11 |
| SE7409506L (enrdf_load_stackoverflow) | 1975-01-27 |
| SE434158B (sv) | 1984-07-09 |
| JPS5041801A (enrdf_load_stackoverflow) | 1975-04-16 |
| HU174054B (hu) | 1979-10-28 |
| BE817735A (fr) | 1974-11-18 |
| FR2245669B1 (enrdf_load_stackoverflow) | 1977-06-24 |
| GB1481881A (en) | 1977-08-03 |
| DE2435619A1 (de) | 1975-02-27 |
| DE2435619C3 (enrdf_load_stackoverflow) | 1980-01-03 |
| PL87546B1 (enrdf_load_stackoverflow) | 1976-07-31 |
| IN140064B (enrdf_load_stackoverflow) | 1976-09-04 |
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