SU483829A3 - Способ получени производных изохинолина - Google Patents
Способ получени производных изохинолинаInfo
- Publication number
- SU483829A3 SU483829A3 SU1637445A SU1637445A SU483829A3 SU 483829 A3 SU483829 A3 SU 483829A3 SU 1637445 A SU1637445 A SU 1637445A SU 1637445 A SU1637445 A SU 1637445A SU 483829 A3 SU483829 A3 SU 483829A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- ethyl
- dioxo
- tetrahydro
- dimethylisoquinolyl
- urea
- Prior art date
Links
- 238000000034 method Methods 0.000 title description 4
- 125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 title description 2
- PBKONEOXTCPAFI-UHFFFAOYSA-N 1,2,4-trichlorobenzene Chemical compound ClC1=CC=C(Cl)C(Cl)=C1 PBKONEOXTCPAFI-UHFFFAOYSA-N 0.000 description 18
- 239000004202 carbamide Substances 0.000 description 12
- -1 ethyl - benzenesulfonyl Chemical group 0.000 description 10
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 7
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 6
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
- PAFZNILMFXTMIY-UHFFFAOYSA-N cyclohexylamine Chemical compound NC1CCCCC1 PAFZNILMFXTMIY-UHFFFAOYSA-N 0.000 description 6
- 159000000000 sodium salts Chemical class 0.000 description 6
- BUXTXUBQAKIQKS-UHFFFAOYSA-N sulfuryl diisocyanate Chemical compound O=C=NS(=O)(=O)N=C=O BUXTXUBQAKIQKS-UHFFFAOYSA-N 0.000 description 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 description 2
- 150000001412 amines Chemical class 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 2
- NMBWXBWFDHVLGS-UHFFFAOYSA-N 2-ethylbenzenesulfonamide Chemical compound CCC1=CC=CC=C1S(N)(=O)=O NMBWXBWFDHVLGS-UHFFFAOYSA-N 0.000 description 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 101100223892 Escherichia coli sulI gene Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 description 1
- 125000003545 alkoxy group Chemical group 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
- 229910052794 bromium Inorganic materials 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- 229940058172 ethylbenzene Drugs 0.000 description 1
- UCYJKCIWSHBAMK-UHFFFAOYSA-N ethylbenzene sulfuryl diisocyanate Chemical compound S(=O)(=O)(N=C=O)N=C=O.C(C)C1=CC=CC=C1 UCYJKCIWSHBAMK-UHFFFAOYSA-N 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- 150000002513 isocyanates Chemical class 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702011126 DE2011126A1 (de) | 1969-04-17 | 1970-03-10 | Isochinolinderivate und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU483829A3 true SU483829A3 (ru) | 1975-09-05 |
Family
ID=5764576
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1637444A SU413675A3 (ru) | 1970-03-10 | 1970-04-10 | Способ получения производных изохинолина |
| SU1637446A SU406352A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-03-10 | 1970-04-10 | |
| SU1637445A SU483829A3 (ru) | 1970-03-10 | 1970-04-10 | Способ получени производных изохинолина |
| SU1637466A SU414789A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-03-10 | 1970-04-10 | |
| SU1637447A SU417942A3 (ru) | 1970-03-10 | 1970-04-10 | Способ получения производных изохинолина |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1637444A SU413675A3 (ru) | 1970-03-10 | 1970-04-10 | Способ получения производных изохинолина |
| SU1637446A SU406352A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-03-10 | 1970-04-10 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1637466A SU414789A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-03-10 | 1970-04-10 | |
| SU1637447A SU417942A3 (ru) | 1970-03-10 | 1970-04-10 | Способ получения производных изохинолина |
Country Status (8)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20090186A2 (hr) | 2009-03-31 | 2010-10-31 | Institut Ruđer Bošković | Adamantanski bisureidni derivati, metoda priprave i primjena u detekciji aniona |
-
1970
- 1970-04-07 CH CH1823972A patent/CH540259A/de not_active IP Right Cessation
- 1970-04-07 BG BG016222A patent/BG17574A3/xx unknown
- 1970-04-07 BG BG016223A patent/BG17575A3/xx unknown
- 1970-04-07 CH CH1823472A patent/CH550174A/xx not_active IP Right Cessation
- 1970-04-07 CH CH1823372A patent/CH540258A/de not_active IP Right Cessation
- 1970-04-07 BG BG1662070A patent/BG17780A3/xx unknown
- 1970-04-10 SU SU1637444A patent/SU413675A3/ru active
- 1970-04-10 SU SU1637446A patent/SU406352A3/ru active
- 1970-04-10 SU SU1637445A patent/SU483829A3/ru active
- 1970-04-10 SU SU1637466A patent/SU414789A3/ru active
- 1970-04-10 SU SU1637447A patent/SU417942A3/ru active
- 1970-04-11 RO RO6578570A patent/RO56309A/ro unknown
- 1970-04-11 RO RO6578770A patent/RO56119A/ro unknown
- 1970-04-11 RO RO6578670A patent/RO57025A/ro unknown
- 1970-04-11 RO RO6578270A patent/RO56615A/ro unknown
- 1970-04-11 RO RO6578870A patent/RO56471A/ro unknown
- 1970-04-11 RO RO6578470A patent/RO57082A/ro unknown
- 1970-04-11 RO RO6578170A patent/RO56517A/ro unknown
- 1970-04-14 CS CS786970A patent/CS162719B2/cs unknown
- 1970-04-14 CS CS786773A patent/CS173645B2/cs unknown
- 1970-04-14 CS CS786270A patent/CS162716B2/cs unknown
- 1970-04-14 CS CS786470A patent/CS162717B2/cs unknown
- 1970-04-14 CS CS786673A patent/CS162718B2/cs unknown
- 1970-04-16 AT AT315871A patent/AT297012B/de not_active IP Right Cessation
- 1970-04-16 ES ES378681A patent/ES378681A1/es not_active Expired
- 1970-04-16 AT AT315671A patent/AT297010B/de not_active IP Right Cessation
- 1970-04-16 ES ES378682A patent/ES378682A1/es not_active Expired
- 1970-04-16 ES ES378683A patent/ES378683A1/es not_active Expired
- 1970-04-16 AT AT315771A patent/AT297011B/de not_active IP Right Cessation
- 1970-04-16 AT AT316071A patent/AT297014B/de not_active IP Right Cessation
- 1970-04-16 AT AT315971A patent/AT297013B/de not_active IP Right Cessation
- 1970-04-17 ES ES378757A patent/ES378757A1/es not_active Expired
- 1970-04-17 ES ES378760A patent/ES378760A1/es not_active Expired
- 1970-04-17 ES ES378755A patent/ES378755A1/es not_active Expired
- 1970-04-17 ES ES378758A patent/ES378758A1/es not_active Expired
- 1970-04-17 ES ES378756A patent/ES378756A1/es not_active Expired
- 1970-04-17 ES ES378759A patent/ES378759A1/es not_active Expired
- 1970-12-07 BG BG016221A patent/BG17573A3/xx unknown
-
1975
- 1975-08-04 YU YU199875A patent/YU37136B/xx unknown
- 1975-08-04 YU YU199775A patent/YU37135B/xx unknown
- 1975-08-04 YU YU200475A patent/YU37140B/xx unknown
- 1975-08-04 YU YU200375A patent/YU37139B/xx unknown
- 1975-08-04 YU YU200075A patent/YU37137B/xx unknown
- 1975-08-04 YU YU199975A patent/YU36929B/xx unknown
- 1975-08-04 YU YU200175A patent/YU200175A/xx unknown
- 1975-08-04 YU YU200275A patent/YU37138B/xx unknown
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