SU423298A3 - СПОСОБ ПОЛУЧЕНИЯПРОИЗВОДНЫХ 2,6-ДИМОРФОЛИНО-8-АЛКАКОЛАМйНО- ПИРИМИДО-[5,4-й']-ПИРИМИДИНА - Google Patents
СПОСОБ ПОЛУЧЕНИЯПРОИЗВОДНЫХ 2,6-ДИМОРФОЛИНО-8-АЛКАКОЛАМйНО- ПИРИМИДО-[5,4-й']-ПИРИМИДИНАInfo
- Publication number
- SU423298A3 SU423298A3 SU1758327A SU1758327A SU423298A3 SU 423298 A3 SU423298 A3 SU 423298A3 SU 1758327 A SU1758327 A SU 1758327A SU 1758327 A SU1758327 A SU 1758327A SU 423298 A3 SU423298 A3 SU 423298A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- pyrimidine
- pyrimido
- alkyl
- general formula
- alkanolamine
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 claims description 10
- 150000001875 compounds Chemical class 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- -1 phenyl OXY, mercapto Chemical group 0.000 claims description 3
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 claims description 3
- 125000000217 alkyl group Chemical group 0.000 claims description 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 2
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims description 2
- 238000000354 decomposition reaction Methods 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 150000003230 pyrimidines Chemical class 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 241001024304 Mino Species 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical compound CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical class CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 1
- WUGQZFFCHPXWKQ-UHFFFAOYSA-N Propanolamine Chemical compound NCCCO WUGQZFFCHPXWKQ-UHFFFAOYSA-N 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 150000001879 copper Chemical class 0.000 description 1
- CKFAFJGSVBYGIM-UHFFFAOYSA-N ethanol;2-methylpropan-2-ol Chemical compound CCO.CC(C)(C)O CKFAFJGSVBYGIM-UHFFFAOYSA-N 0.000 description 1
- 125000001475 halogen functional group Chemical group 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 238000005065 mining Methods 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702004202 DE2004202A1 (de) | 1970-01-30 | 1970-01-30 | Neue 2,6-Dimorpholino-8-alkanolamino-pyrimido[5,4-d]pyrimidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU423298A3 true SU423298A3 (ru) | 1974-04-05 |
Family
ID=5760962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1758327A SU423298A3 (ru) | 1970-01-30 | 1971-01-25 | СПОСОБ ПОЛУЧЕНИЯПРОИЗВОДНЫХ 2,6-ДИМОРФОЛИНО-8-АЛКАКОЛАМйНО- ПИРИМИДО-[5,4-й']-ПИРИМИДИНА |
Country Status (16)
| Country | Link |
|---|---|
| AT (2) | AT302343B (enExample) |
| AU (1) | AU2476671A (enExample) |
| BE (1) | BE762328A (enExample) |
| BG (1) | BG18611A3 (enExample) |
| DE (1) | DE2004202A1 (enExample) |
| DK (1) | DK126653B (enExample) |
| ES (2) | ES387123A1 (enExample) |
| FR (1) | FR2081472A1 (enExample) |
| GB (1) | GB1280288A (enExample) |
| HU (1) | HU163361B (enExample) |
| IE (1) | IE34922B1 (enExample) |
| IL (1) | IL36096A0 (enExample) |
| NL (1) | NL7101117A (enExample) |
| RO (2) | RO57988A7 (enExample) |
| SU (1) | SU423298A3 (enExample) |
| ZA (1) | ZA71578B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1051445B (it) | 1975-07-16 | 1981-04-21 | Recordati Chem Pharm | Derivati dell.acido benzoico terapeuticamente attivi e procedimento per prepararli |
| DE102008046396B4 (de) | 2008-09-09 | 2011-11-10 | Leica Biosystems Nussloch Gmbh | Vorrichtung zum Kühlen von Gewebeproben enthaltenden Kassettenmagazinen |
-
1970
- 1970-01-30 DE DE19702004202 patent/DE2004202A1/de active Pending
-
1971
- 1971-01-09 ES ES387123A patent/ES387123A1/es not_active Expired
- 1971-01-12 RO RO68284A patent/RO57988A7/ro unknown
- 1971-01-12 RO RO65572A patent/RO57780A7/ro unknown
- 1971-01-25 SU SU1758327A patent/SU423298A3/ru active
- 1971-01-25 DK DK30771AA patent/DK126653B/da unknown
- 1971-01-26 BG BG016662A patent/BG18611A3/xx unknown
- 1971-01-28 NL NL7101117A patent/NL7101117A/xx unknown
- 1971-01-28 AU AU24766/71A patent/AU2476671A/en not_active Expired
- 1971-01-29 ZA ZA710578A patent/ZA71578B/xx unknown
- 1971-01-29 AT AT942971A patent/AT302343B/de not_active IP Right Cessation
- 1971-01-29 BE BE762328A patent/BE762328A/xx unknown
- 1971-01-29 IE IE107/71A patent/IE34922B1/xx unknown
- 1971-01-29 FR FR7103039A patent/FR2081472A1/fr not_active Withdrawn
- 1971-01-29 HU HUTO842A patent/HU163361B/hu unknown
- 1971-01-29 IL IL36096A patent/IL36096A0/xx unknown
- 1971-01-29 AT AT76871A patent/AT301562B/de not_active IP Right Cessation
- 1971-04-19 GB GB20659/71A patent/GB1280288A/en not_active Expired
- 1971-07-19 ES ES393417A patent/ES393417A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE762328A (fr) | 1971-07-29 |
| ES393417A1 (es) | 1974-09-16 |
| ZA71578B (en) | 1971-11-24 |
| ES387123A1 (es) | 1973-05-16 |
| NL7101117A (enExample) | 1971-08-03 |
| GB1280288A (en) | 1972-07-05 |
| DE2004202A1 (de) | 1971-08-05 |
| AT301562B (de) | 1972-09-11 |
| HU163361B (enExample) | 1973-07-28 |
| IL36096A0 (en) | 1971-03-24 |
| IE34922L (en) | 1971-07-30 |
| RO57988A7 (enExample) | 1975-06-15 |
| RO57780A7 (enExample) | 1975-03-15 |
| AT302343B (de) | 1972-10-10 |
| FR2081472A1 (enExample) | 1971-12-03 |
| IE34922B1 (en) | 1975-09-17 |
| AU2476671A (en) | 1972-08-03 |
| SU383298A3 (enExample) | 1973-05-25 |
| DK126653B (da) | 1973-08-06 |
| BG18611A3 (bg) | 1975-02-25 |
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