SU325231A1 - METHOD OF OBTAINING | 3- (N, N-DIIZOPROPILAMIHO) ETYL-ACETATE - Google Patents
METHOD OF OBTAINING | 3- (N, N-DIIZOPROPILAMIHO) ETYL-ACETATEInfo
- Publication number
- SU325231A1 SU325231A1 SU1454847A SU1454847A SU325231A1 SU 325231 A1 SU325231 A1 SU 325231A1 SU 1454847 A SU1454847 A SU 1454847A SU 1454847 A SU1454847 A SU 1454847A SU 325231 A1 SU325231 A1 SU 325231A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- diizopropilamiho
- etyl
- acetate
- obtaining
- ketene
- Prior art date
Links
- XEKOWRVHYACXOJ-UHFFFAOYSA-N acetic acid ethyl ester Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
- CCGKOQOJPYTBIH-UHFFFAOYSA-N Ethenone Chemical compound C=C=O CCGKOQOJPYTBIH-UHFFFAOYSA-N 0.000 description 5
- 238000004821 distillation Methods 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 3
- 150000001414 amino alcohols Chemical class 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- ZRUPXAZUXDFLTG-UHFFFAOYSA-N 1-aminopentan-2-ol Chemical compound CCCC(O)CN ZRUPXAZUXDFLTG-UHFFFAOYSA-N 0.000 description 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- ZYWUVGFIXPNBDL-UHFFFAOYSA-N N,N-Diisopropylaminoethanol Chemical compound CC(C)N(C(C)C)CCO ZYWUVGFIXPNBDL-UHFFFAOYSA-N 0.000 description 1
- 235000015450 Tilia cordata Nutrition 0.000 description 1
- 235000011941 Tilia x europaea Nutrition 0.000 description 1
- 125000003342 alkenyl group Chemical group 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
Description
Предлагаетс способ получени новых эфиров аминоспиртов. Эти соединени могут найти применение в качестве растворителей, пластификаторов .A method for the preparation of new amino alcohol esters is proposed. These compounds can be used as solvents, plasticizers.
В литературе описаны различные эфиры аминоспиртов, в частности известен способ получени производных алканоламннов или их эфиров, заключающийс во взаимодействии соединени формулыThe literature describes various esters of amino alcohols, in particular, a method for the preparation of alkanolamine derivatives or their esters is known, which consists in the interaction of a compound of the formula
,А,BUT
где R - гетероциклический радикал;where R is a heterocyclic radical;
/0 АСН-СНа или --СНОН-CHjZ/ 0 ACH-CH or -SHON-CHjZ
где Z - галоген, с амином формулы NH2Riwhere Z is halogen, with an amine of the formula NH2Ri
где RI - алкил, циклоалкил, алкенил или арал кил.where RI is alkyl, cycloalkyl, alkenyl or aral kil.
Однако в литературе отсутствуют сведени о получений р- (М,М-диизопропиламино) этилацетата , который может найти широкое применение .However, in the literature there is no information on the preparation of p- (M, M-diisopropylamino) ethyl acetate, which can be widely used.
пропилэтаноламин насыщают кетеном при 65°С с последующим выделением целевого продукта известным способом, например персгонкой под вакуумом при 125-127°С/ 0,1 мм рт. ст. Выход целевого продукта 85%.propylethanolamine is saturated with ketene at 65 ° C, followed by separation of the target product in a known manner, for example, by distillation under vacuum at 125-127 ° C / 0.1 mm Hg. Art. The yield of the target product is 85%.
Пример. Дл проведени основной реакции помещают 145 г (1 г-мо.гь) N,N-диизoпpoпилэтаноламина в трехгорлую колбу, снабженную обратным холодильником, отводной трубкой дл ввода кетена и термометром. В колбу с К,К-диизопропилэтанолам11ном ири обычных услови х пропускают кетен в течение 2 час, так как выход кетена на «лампеExample. For the main reaction, 145 g (1 g-m) of N, N-diisopropylethanolamine is placed in a three-neck flask equipped with a reflux condenser, a branch pipe for the introduction of ketene and a thermometer. In a flask with K, K-diisopropylethanol irim and normal conditions, ketene is passed through for 2 hours, since the ketene output on the lamp
42 г (1 г-.ноль) за это врем .42 g (1 g -nol) during this time.
При пропускании кетена реакционна смесь разогреваетс и температура достигает 65° С. Полученную смесь сразу же перегон ют под вакуумом при 125-127° С/0,1 мм рт. ст. Продукт , выдел емый перегонкой, совершенно бесцветен, легко раствор ет резииу и иластмассы , органические красители и другие оргаиические соединени . Выход 85-уо от теоретического , dy 1,0372; r;g 1,4550.By passing ketene, the reaction mixture is heated and the temperature reaches 65 ° C. The resulting mixture is immediately distilled under vacuum at 125-127 ° C / 0.1 mm Hg. Art. The product released by distillation is completely colorless, easily dissolving resilium and elastics, organic dyes and other organic compounds. Output 85-yo from theoretical, dy 1.0372; r; g 1.4550.
Найдено, %: N 7,6. CioHaiOiN. Вычислено, %: N 7,49. 3 Предмет изобретени 1. Способ получеии |3-(Ы,Ы-диизопропиламино )этилацетата, отличающийс тем, что . М,Ы-диизопропилэтаноламин насыщают кете- 5 ном с последующим выделением целевого про4 дукта известиым способом, иапример, перегонкой под вакуумом. 2. Способ по п. 1, отличающийс тем, что перегонку под вакуумом осуществл ют при 125-127° С/0,1 мм рт. ст.Found,%: N 7.6. CioHaiOiN. Calculated,%: N 7.49. 3 Subject of the invention 1. Method for producing | 3- (S, S-diisopropylamino) ethyl acetate, characterized in that. M, N-diisopropylethanolamine is saturated with keto-5 and subsequent separation of the target product by the lime method, for example, by distillation under vacuum. 2. A method according to claim 1, characterized in that the distillation under vacuum is carried out at 125-127 ° C / 0.1 mm Hg. Art.
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU325231A1 true SU325231A1 (en) |
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