SU1651527A3 - 2,2-(2,5-dioxopiperazinyl-1,4)-diacetic acid diamide showing antihypoxanthant activity and improving conditioned reflex reproduction - Google Patents

2,2-(2,5-dioxopiperazinyl-1,4)-diacetic acid diamide showing antihypoxanthant activity and improving conditioned reflex reproduction

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Publication number
SU1651527A3
SU1651527A3 SU4758625/04A SU4758625A SU1651527A3 SU 1651527 A3 SU1651527 A3 SU 1651527A3 SU 4758625/04 A SU4758625/04 A SU 4758625/04A SU 4758625 A SU4758625 A SU 4758625A SU 1651527 A3 SU1651527 A3 SU 1651527A3
Authority
SU
USSR - Soviet Union
Prior art keywords
dioxopiperazinyl
diacetic acid
conditioned reflex
antihypoxanthant
activity
Prior art date
Application number
SU4758625/04A
Other languages
Russian (ru)
Inventor
Ю.И. Башнин
Г.Н. Кожухарь
Е.А. Вальдман
Ю.Г. Бобков
С.М. Дудкин
П.В. Полев
Original Assignee
Научно-производственный центр медицинской биотехнологии
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Научно-производственный центр медицинской биотехнологии filed Critical Научно-производственный центр медицинской биотехнологии
Priority to SU4758625/04A priority Critical patent/SU1651527A3/en
Application granted granted Critical
Publication of SU1651527A3 publication Critical patent/SU1651527A3/en

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Abstract

FIELD: organic chemistry. SUBSTANCE: synthesis is carried out by reaction of cooled to 0 C solution of 2,2-(2,5-dioxopiperazinyl-1,4)-diacetic acid diethyl ester in the medium of absolute methanol with dry NH(saturation for 40 min). Yield is 82.4%, m. p. is 313-315 C, empirical formula is CHNO, toxicity LDis above 1000 mg/kg. New substance shows protective effect against damage factors of histotoxic hypoxia, acute hypobaric hypoxia, improves conditioned reflex reproduction without effect on the processes of teaching and memorizing in mice. Synthesized compound can be used in medicine. EFFECT: synthesis of new compound indicated above. 4 tbl
SU4758625/04A 1989-11-16 1989-11-16 2,2-(2,5-dioxopiperazinyl-1,4)-diacetic acid diamide showing antihypoxanthant activity and improving conditioned reflex reproduction SU1651527A3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU4758625/04A SU1651527A3 (en) 1989-11-16 1989-11-16 2,2-(2,5-dioxopiperazinyl-1,4)-diacetic acid diamide showing antihypoxanthant activity and improving conditioned reflex reproduction

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU4758625/04A SU1651527A3 (en) 1989-11-16 1989-11-16 2,2-(2,5-dioxopiperazinyl-1,4)-diacetic acid diamide showing antihypoxanthant activity and improving conditioned reflex reproduction

Publications (1)

Publication Number Publication Date
SU1651527A3 true SU1651527A3 (en) 1996-01-10

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ID=60531661

Family Applications (1)

Application Number Title Priority Date Filing Date
SU4758625/04A SU1651527A3 (en) 1989-11-16 1989-11-16 2,2-(2,5-dioxopiperazinyl-1,4)-diacetic acid diamide showing antihypoxanthant activity and improving conditioned reflex reproduction

Country Status (1)

Country Link
SU (1) SU1651527A3 (en)

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