Научно-производственный центр медицинской биотехнологии
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
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FIELD: organic chemistry. SUBSTANCE: synthesis is carried out by reaction of cooled to 0 C solution of 2,2-(2,5-dioxopiperazinyl-1,4)-diacetic acid diethyl ester in the medium of absolute methanol with dry NH(saturation for 40 min). Yield is 82.4%, m. p. is 313-315 C, empirical formula is CHNO, toxicity LDis above 1000 mg/kg. New substance shows protective effect against damage factors of histotoxic hypoxia, acute hypobaric hypoxia, improves conditioned reflex reproduction without effect on the processes of teaching and memorizing in mice. Synthesized compound can be used in medicine. EFFECT: synthesis of new compound indicated above. 4 tbl
Procedure for the obtaining of 2-acetoxibenzoatos of n (2-hydroxythyl) amidas of fatty acids. (Machine-translation by Google Translate, not legally binding)