SU1585707A1 - Method of diagnosis of t-immunodeficiency - Google Patents
Method of diagnosis of t-immunodeficiency Download PDFInfo
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- SU1585707A1 SU1585707A1 SU884434833A SU4434833A SU1585707A1 SU 1585707 A1 SU1585707 A1 SU 1585707A1 SU 884434833 A SU884434833 A SU 884434833A SU 4434833 A SU4434833 A SU 4434833A SU 1585707 A1 SU1585707 A1 SU 1585707A1
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- immunodeficiency
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Изобретение позвол ет упростить дифференциальную диагностику Т-иммунодефицитов и модификации Е-рецепторов лимфоцитов, повысить ее эффективность. Способ осуществл етс путем одномоментного исследовани двух параметров: содержани Е-РОК и неспецифической кислой эстеразы в лимфоцитах и по их сечению проводить дифференциацию указанных состо ний, что упрощает и повышает эффективность диагностики. Данный способ может быть применен в широкой клинической практике дл дифференциальной диагностики Т-иммунодефицитов.The invention allows to simplify the differential diagnosis of T-immunodeficiencies and modification of E-receptors of lymphocytes, to increase its effectiveness. The method is carried out by simultaneously examining two parameters: the content of E-ROCK and nonspecific acid esterase in lymphocytes and, according to their cross-section, to carry out the differentiation of these conditions, which simplifies and improves the efficiency of diagnosis. This method can be applied in a wide clinical practice for the differential diagnosis of T-immunodeficiency.
Description
Изобретение относитс к медицине, в частности к диагностике иммунодефицитов.This invention relates to medicine, in particular to the diagnosis of immunodeficiencies.
Цель изобретени - повышение точности дифференциации Т-иммунодефицита от Е-рецепторов.The purpose of the invention is to improve the accuracy of differentiation of T-immunodeficiency from E-receptors.
П р и м е р 1. Больна С. Диагноз: ревма- тоидный артрит. При исследовании обнаружено снижение количества Е-ро- зеткообразующих клеток на 45%. содержани клеток, дающих реакцию на неспецифически кислую зстеразу, - на 25%. Показатель БТЛ снижен. Инкубаци клеток с левомизолом к повышению числа Е-розет- кообразующих клеток не привела.PRI me R 1. Sick S. Diagnosis: rheumatoid arthritis. The study found a decrease in the number of E-rosette-forming cells by 45%. the content of cells that respond to nonspecific acid zsterase is 25%. Indicator BTL reduced. Incubation of cells with levomisole did not lead to an increase in the number of E-rosetting cells.
По снижению первых двух показателей согласно предлагаемому способу диагностирован Т-иммунодефицит.To reduce the first two indicators according to the proposed method, T-immunodeficiency was diagnosed.
П р и м е р 2, Больна Г. Диагноз: ревматизм . При исследовании обнаружено снижение уровн Е-розеткообразующих клеток на 45%. Содержание клеток с положительной реакцией на неспецифическую кислую зстеразу не изменено.PRI me R 2, Sick G. Diagnosis: rheumatism. The study found a decrease in the level of E-rosette-forming cells by 45%. The content of cells with a positive reaction to nonspecific acid zsterase is not changed.
Согласно предлагаемому способу результаты исследовани свидетельствуют о модификации Е-рецепторов и отсутствии Т-иммунодефицита. что подтверждаетс другими методами исследовани .According to the proposed method, the results of the study indicate a modification of the E-receptors and the absence of T-immunodeficiency. which is confirmed by other research methods.
Так. при инкубации клеток с левомизолом количество Е-розеткообразующих клеток возросло до показателей здоровых лиц; показатели реакции лимфоцитов на ФГА не отличались от показателей референтной группы.So. when cells were incubated with levomisole, the number of E-rosetting cells increased to the values of healthy individuals; indicators of lymphocyte response to PHA did not differ from those of the reference group.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU884434833A SU1585707A1 (en) | 1988-05-31 | 1988-05-31 | Method of diagnosis of t-immunodeficiency |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU884434833A SU1585707A1 (en) | 1988-05-31 | 1988-05-31 | Method of diagnosis of t-immunodeficiency |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1585707A1 true SU1585707A1 (en) | 1990-08-15 |
Family
ID=21378956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU884434833A SU1585707A1 (en) | 1988-05-31 | 1988-05-31 | Method of diagnosis of t-immunodeficiency |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU1585707A1 (en) |
-
1988
- 1988-05-31 SU SU884434833A patent/SU1585707A1/en active
Non-Patent Citations (1)
| Title |
|---|
| Неприна Т.е.. Пантелеева Е.С.Ярилин А.А., Филатов Н.П. Модификаци Е-рецепторов циркулирующих Т-лимфоцитов в норме и при онкологических заболевани х. * |
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