SMT201400186B - Peptidi derivati da fviii e loro uso nella tolleranza immunologica negli emofiliaci - Google Patents

Peptidi derivati da fviii e loro uso nella tolleranza immunologica negli emofiliaci

Info

Publication number
SMT201400186B
SMT201400186B SM201400186T SM201400186T SMT201400186B SM T201400186 B SMT201400186 B SM T201400186B SM 201400186 T SM201400186 T SM 201400186T SM 201400186 T SM201400186 T SM 201400186T SM T201400186 B SMT201400186 B SM T201400186B
Authority
SM
San Marino
Prior art keywords
hemophiliacs
fviii
peptides derived
immunological tolerance
immunological
Prior art date
Application number
SM201400186T
Other languages
English (en)
Italian (it)
Inventor
David Wraith
Original Assignee
Apitope Int Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40834163&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201400186(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Apitope Int Nv filed Critical Apitope Int Nv
Publication of SMT201400186B publication Critical patent/SMT201400186B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SM201400186T 2009-05-18 2014-12-15 Peptidi derivati da fviii e loro uso nella tolleranza immunologica negli emofiliaci SMT201400186B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0908515.0A GB0908515D0 (en) 2009-05-18 2009-05-18 Peptide
EP10721533A EP2432494A2 (en) 2009-05-18 2010-05-17 Peptide

Publications (1)

Publication Number Publication Date
SMT201400186B true SMT201400186B (it) 2015-01-15

Family

ID=40834163

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201400186T SMT201400186B (it) 2009-05-18 2014-12-15 Peptidi derivati da fviii e loro uso nella tolleranza immunologica negli emofiliaci

Country Status (30)

Country Link
US (1) US8703705B2 (https=)
EP (2) EP2432494A2 (https=)
JP (1) JP5784009B2 (https=)
KR (1) KR101673889B1 (https=)
CN (1) CN102458445B (https=)
AU (1) AU2010250957B2 (https=)
BR (1) BRPI1012845A2 (https=)
CA (1) CA2762020C (https=)
CL (1) CL2011002893A1 (https=)
CO (1) CO6460780A2 (https=)
CY (1) CY1115832T1 (https=)
DK (1) DK2465523T3 (https=)
EA (1) EA027229B1 (https=)
EC (1) ECSP11011540A (https=)
ES (1) ES2525448T3 (https=)
GB (1) GB0908515D0 (https=)
HR (1) HRP20141182T1 (https=)
IL (1) IL216199A (https=)
MX (1) MX2011012270A (https=)
MY (1) MY168207A (https=)
NZ (2) NZ613713A (https=)
PL (1) PL2465523T3 (https=)
PT (1) PT2465523E (https=)
RS (1) RS53671B1 (https=)
SG (2) SG190573A1 (https=)
SI (1) SI2465523T1 (https=)
SM (1) SMT201400186B (https=)
UA (1) UA110921C2 (https=)
WO (1) WO2010133834A2 (https=)
ZA (1) ZA201108446B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2506868T1 (en) 2009-12-06 2018-04-30 Bioverativ Therapeutics Inc. HYPER AND HYBRID POLYPETTIDES FACTOR VIII-FC AND METHODS FOR THEIR USE
EA036483B1 (ru) * 2012-11-12 2020-11-16 Эпитоп Интернэшнл Нв Пептиды, способные индуцировать толерантность к рекомбинантному fviii, содержащая их композиция, их применение и способ лечения гемофилии
GB201314052D0 (en) * 2013-08-06 2013-09-18 Apitope Int Nv Peptides
PE20231949A1 (es) 2015-10-30 2023-12-05 Spark Therapeutics Inc VARIANTES DEL FACTOR VIII REDUCIDO CON CpG, COMPOSICIONES Y METODOS Y USOS PARA EL TRATAMIENTO DE TRASTORNOS DE LA HEMOSTASIA
MX2019006444A (es) 2016-12-02 2019-10-30 Bioverativ Therapeutics Inc Métodos de tratamiento de artropatía hemofílica utilizando factores de coagulación quiméricos.
PL3793588T3 (pl) 2018-05-18 2025-09-01 Bioverativ Therapeutics Inc. Sposoby leczenia hemofilii a

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102764425B (zh) 2000-08-21 2015-11-25 阿皮托普技术(布里斯托尔)有限公司 肽选择方法
AU2002249779A1 (en) * 2000-12-01 2002-08-12 Regents Of The University Of Minnesota Method to treat hemophilia
WO2002096454A1 (en) 2001-05-31 2002-12-05 D. Collen Research Foundation Vzw Recombinant molecules with reduced immunogenicity, methods and intermediates for obtaining them and their use in pharmaceutical compositions and diagnostic tools
WO2002098454A2 (en) 2001-05-31 2002-12-12 D. Collen Research Foundation Vzw Onderwijsen Navorsing Campus Gasthuisberg K.U. Leuven Recombinant molecules with reduced immunogenicity, methods and intermediates for obtaining them and their use in pharmaceutical compositions and diagnostic tools
WO2003087161A1 (en) 2002-04-18 2003-10-23 Merck Patent Gmbh Modified factor viii
GB0723712D0 (en) * 2007-12-04 2008-01-16 Apitope Technology Bristol Ltd Peptides
GB0801513D0 (en) * 2008-01-28 2008-03-05 Circassia Ltd Peptides from factor VIII

Also Published As

Publication number Publication date
WO2010133834A2 (en) 2010-11-25
ES2525448T3 (es) 2014-12-23
SG190573A1 (en) 2013-06-28
AU2010250957A1 (en) 2011-12-01
PT2465523E (pt) 2014-12-09
JP5784009B2 (ja) 2015-09-24
CY1115832T1 (el) 2017-01-25
CA2762020A1 (en) 2010-11-25
MX2011012270A (es) 2011-12-12
CO6460780A2 (es) 2012-06-15
RS53671B1 (sr) 2015-04-30
UA110921C2 (uk) 2016-03-10
IL216199A (en) 2015-11-30
KR101673889B1 (ko) 2016-11-08
ECSP11011540A (es) 2012-01-31
BRPI1012845A2 (pt) 2016-10-11
CL2011002893A1 (es) 2012-08-17
EA201171430A1 (ru) 2012-05-30
US20120121625A1 (en) 2012-05-17
SG176138A1 (en) 2011-12-29
PL2465523T3 (pl) 2015-03-31
US8703705B2 (en) 2014-04-22
NZ613713A (en) 2014-10-31
GB0908515D0 (en) 2009-06-24
EP2465523B1 (en) 2014-10-01
HRP20141182T1 (hr) 2015-02-13
JP2012527440A (ja) 2012-11-08
EA027229B1 (ru) 2017-07-31
SI2465523T1 (sl) 2015-02-27
EP2432494A2 (en) 2012-03-28
HK1173358A1 (en) 2013-05-16
EP2465523A1 (en) 2012-06-20
MY168207A (en) 2018-10-15
IL216199A0 (en) 2012-01-31
CA2762020C (en) 2018-08-28
DK2465523T3 (en) 2014-12-15
KR20120023023A (ko) 2012-03-12
AU2010250957B2 (en) 2015-01-15
CN102458445A (zh) 2012-05-16
WO2010133834A3 (en) 2011-02-24
NZ596300A (en) 2013-08-30
CN102458445B (zh) 2014-06-11
ZA201108446B (en) 2013-01-30

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