SK6882Y1 - Cosmetic preparation with stem cells in combination with peptides - Google Patents

Abstract

A cosmetic preparation with plant stem cells in combination of peptides, to improve the functional properties of the skin, comprising acetyl hexapeptid-8, pentapeptid-18, oligopeptid-24, tripeptid-10 citrulin, tripeptid-1, acetyl hexapeptid-4, extract of the enzyme Pseudoalteromonas, hydrolyzed wheat protein, hydrolyzed soy protein, extract of Malus Domestica plant cell culture, sodium hyaluronate and N,N-dimethylaminoethanol.

Description

The invention relates to a plant stem cell cosmetic composition in combination with peptides for improving the functional properties of the skin, which, depending on the desired mode of application, can be in the form of a serum, emulsion, gel or solution.

BACKGROUND OF THE INVENTION

The aging of the skin results in a deterioration of its functional properties, which is accompanied by certain biochemical, histological and physiological changes that are more intense when exposed to the environment. This deterioration is also due to other factors such as skin stretching due to gravity, constant lending pressure on the facial skin, for example during sleep, or repeated facial movements induced by contracting the muscles of facial expressions. Muscles contract when they receive acetylcholine, which is released from vesicles in a process known as neural exocytosis. The aim of the present invention is to improve the skin's skin properties, stability and wrinkle resistance.

The essence of the technical solution

The object of the invention is a cosmetic composition for improving the functional properties of the skin with plant stem cells and peptides. The essence of the invention is that the cosmetic composition comprises the following combination of active ingredients: acetyl hexapeptide-8 in an amount of 0.005% by weight, pentapeptide-18 in an amount of 0.003% by weight, oligopeptide-24 in an amount of 0.0025% by weight, tripeptide -10 citrulline in an amount of 0.0012 wt%, tripeptide-1 in an amount of 0.0003 wt%, acetyl heptapeptide-4 in an amount of 0.0025 wt%, extract of Pseudoalteromonas ferment in an amount of 0.36 wt%, hydrolyzed wheat protein at 0.09 wt%, hydrolyzed soy protein at 0.06 wt%, extract from Malus Domestica plant stem cell culture at 0.225 wt%, sodium hyaluronic acid (Sodium Hyaluronate) at 1, And Ν, Ν-dimethylamino ethanol in an amount of 0.5 wt.

Acetyl hexapeptide-8 retains muscle contraction signals and minimizes wrinkles. Pentapeptide-18 has a profound effect on reducing and releasing muscle contraction. Oligopeptide-24 plays a central role in wrinkle reduction and promotes the formation of new skin cells. It improves skin elasticity and replenishes with energy and vitality. Tripeptide-10 Citrulin acts as a skin conditioner. Tripeptide-1 counteracts mimic wrinkles and relaxes the facial muscles. Acetyl-heptapeptide-4 reduces the deep wrinkles caused by muscle contraction, especially around the eyes and forehead. Pseudoalteromonas extract extract acts on the ragged layer of the skin and prevents it from drying out. Hydrolyzed wheat protein and hydrolyzed soy protein are antistatic additives. Plant stem cell culture extract Malus Domestica ensures skin cell life, improves skin tone and minimizes skin deficiencies. Sodium salt of hyaluronic acid (Sodium Hyaluronate) has a moisturizing effect. Ν, Ν-dimethylamino ethanol stimulates phosphatidycholine synthesis, is an important component of cell membranes and regulates viscosity.

A biotechnology serum, emulsion, gel or solution cosmetic smoothes the skin and visibly reduces wrinkles. The cosmetic product is enriched with a nanobiotechnological complex that restores the skin by activating the user's own stem cells. In addition to stem cell-based active ingredients, the cosmetic composition also contains peptides with intensive anti-wrinkle, regenerative and nourishing action.

Stem cell technology is a groundbreaking, unique and exceptional form of skin care. The invention involves a combination of stem cells with skin activators. Plant stem cell culture extract Malus Domestica is a liposomal preparation based on unique stem cells of Uttwiler Spätlauber. Thanks to special technology it is possible to obtain stem cells and incorporate them into cosmetic products to ensure longevity of skin cells. This protects human cells, which manifests itself in slowing the aging of the skin.

Plant stem cell extract from Swiss apple (Malus Domestica): During research conducted in Switzerland, scientists have noticed a very rare type of apple tree (Uttwiler Spätlauber), whose fruits retain their freshness for a very long time. Scientists have found that this is probably due to the very long viability of apple stem cells. Swiss apple stem cells transmit such genetic information to the deepest cells of the skin that delay the chronological process of skin aging and support regenerative and protective processes. Research work carried out on human stem cells confirmed that

SK 6882 Υ1 already 0.01% yield activates stem cells that contribute to skin renewal. In vivo studies carried out in volunteers show that wrinkle depth is reduced already after 28 days of use.

The result is cosmetic products that provide and support:

- protecting the longevity of skin stem cells, slowing down the aging of important cells,

- reducing and slowing down the progressive natural cell aging, maintaining a youthful appearance and skin vitality.

EXAMPLES

Example 1 - anti-mimic wrinkle stem cell serum • Water in an amount of 35.30 wt.

Glycerin in an amount of 11.00 wt.

• Argirelin solution at 10.00% by weight: active substance acetyl hexapeptide-8 at 0.05% by weight, • Leuphasyl solution at 6.00% by weight: active substance pentapeptide-18 at 0.05% by weight • 5.00% Snap7 solution: 0.05% acetyl heptapeptide-4 active substance; 5.00% CG-NanoEDP3 solution: 5. oligopeptide-24 active substance % in an amount of 0.05 wt.

Panthenol in an amount of 5.00 wt.

• Lipomoist 2013 CPE solution in an amount of 3.50% by weight: water, xanthan gum (Xanthan Gum), caprylyl glycol, phenoxyethanol, glucose, carrageenan (Carrageenan), ethylhexyl glycerin • Trylagen PCB solution in an amount of 3.00% by weight: active ingredient Pseudoalteromonas ferment extract in an amount of 12% by weight, hydrolyzed wheat protein in an amount of 3% by weight, hydrolyzed soy protein in an amount of 2% by weight, tripeptide-10 citrulline in an amount of 0.04% by weight, tripeptide-1 in an amount 0.01% by weight; propylene glycol in an amount of 3.00% by weight;

Citrustem ™ solution at 2.50% by weight: water, glycerine, Citrus Aurantium Dulcis (Orange) Callus Culture Extract, xanthan gum (Xanthan Gum), sodium benzoate (Sodium Benzoate), gluconolactone, calcium gluconate (Calcium Gluconate) • PhytoCellTec ™ Malus Domestica in an amount of 2.50% by weight: active ingredient extract from the plant stem cell culture of Malus Domestica in an amount of 9% by weight.

Sodium Hyaluronic Acid (Sodium Hyaluronate) in an amount of 1.50 wt.

Polysorbate in an amount of 4.00 wt.

Phenoxyethanol, ethylhexyl glycerin in an amount of 0.50 wt.

Ν, Ν-dimethylamino ethanol in an amount of 0.50 wt.

Carbomer in an amount of 0.40 wt.

Imidurea (Imidazolidinyl Urea) in an amount of 0.20 wt.

Tocopheryl acetate in an amount of 0.20 wt.

Retinyl Palmitate in an amount of 0.10 wt.

Triethanolamine to pH 5.0 to 7.0 in an amount of 0.60 wt.

Perfume in an amount of 0.20 wt.

Biotechnology serum smoothes the skin and visibly reduces wrinkles. The serum is enriched with a nanobiotechnological complex that renews the skin by activating our stem cells. In addition to stem cell-based active substances, serum also contains peptides with intensive anti-wrinkle, regenerative and nourishing effects.

Example 2 - emulsion with stem cells for pigment spots (composition per 100 g of product) • Water in an amount of 31.20 wt.

Argirelin solution in an amount of 10.00% by weight: active substance acetyl hexapeptide-8 in an amount of 0.05% by weight.

• Melaclear solution in an amount of 8.00% by weight: active ingredient, Glycerin-Aqua-Ditiaoctanediol-Gluconic Acid-Sutilains-Beta-Carotene • Leuphasyl solution in an amount of 6.00% by weight: active ingredient pentapeptide-18 in amount 0, 05 wt.

Snap7 solution in an amount of 5.00% by weight: the active substance acetyl-heptapeptide-4 in an amount of 0.05% by weight.

CG-NanoEDP3 solution in an amount of 5.00% by weight: active ingredient oligopeptide-24 in an amount of 0.05% by weight.

• Etiolin in 5.00% by weight: glycerine, Butylene Glycol, Arctostafylos Uva Ursi Leaf Extract, Mitracarpus Scaber • Trylagen PCB solution in 3.00% by weight: active ingredient Pseudoalteromonas ferment extract in 12% by weight, hydrolyzed wheat protein at 3% by weight, hydrolyzed soy protein at 2% by weight, tripeptide-10 citrulline at 0.04% by weight, tripeptide-1 at 0.01% by weight, • liquid paraffin (Paraffinum liquidum) % in an amount of 3.00 wt.

Polyacrylamide, C12.14 Isoparaffin, Lauret-7 in an amount of 3.00 wt.

Water, titanium dioxide in an amount of 3.00 wt.

Citrustem ™ water solution at 2.50% by weight: water, glycerine, Citrus Aurantium Dulcis (Orange), Callus Culture Extract, Xanthan gum (Xanthan Gum), Sodium benzoate (Sodium Benzoate), Gluconolactone, Calcium Gluconate PhytoCellTec ™ Malus Domestica in an amount of 2.50% by weight; active substance extract from a plant stem cell culture of Malus Domestica in an amount of 9 wt.

Glycerin in an amount of 2.00 wt.

% Sodium hyaluronic acid (Sodium Hyaluronate) in an amount of 1.50 wt.

Isopropyl myristate in an amount of 1.50 wt.

Dimethicone in an amount of 1.50 wt.

Kapryl / caprine triglyceride in an amount of 1.50 wt.

Phenoxyethanol, ethylhexyglycerin in an amount of 1.00 wt.

Octyl methoxycinamate in an amount of 1.00 wt.

C1244 Pareth-30 in an amount of 0.80 wt.

Glyceryl stearate in an amount of 0.70 wt.

Ν, Ν-dimethylamino ethanol in an amount of 0.50 wt.

Butyl methoxydibenzoylmethane in an amount of 0.50 wt.

Benzyl alcohol (Benzyl alcohol), 5-chloro-2-methyl-4-isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one in an amount of 0.10 wt.

Perfume in an amount of 0.20 wt.

The biotechnological emulsion suppresses the formation of melanin in the skin, thus unifying the skin tone. It brightens pigment spots, prevents further imperfections on the skin and protects the skin from premature aging. Helps prevent skin damage from UV radiation.

Example 3 - anti-mimic wrinkle stem cell cleansing gel (composition per 100 g of product) Water in an amount of 49.60 wt.

Polysorbate 20 in an amount of 4.00 wt.

Argirelin solution in an amount of 10.00% by weight: active substance acetyl hexapeptide-8 in an amount of 0.05% by weight.

Leuphasyl solution in an amount of 6.00% by weight: pentapeptide-18 active ingredient in an amount of 0.05% by weight.

Snap7 solution in an amount of 5.00% by weight: water, acetyl heptapeptide-4 active ingredient in an amount of 0.05% by weight.

CG-NanoEDP3 solution in an amount of 5.00% by weight: active ingredient oligopeptide-24 in an amount of 0.05% by weight.

• Lipomoist 2013 CPE solution in an amount of 3.50% by weight: water, xanthan gum (Xanthan Gum), caprylyl glycol, phenoxyethanol, glucose, carrageenan (Carrageenan), ethylhexyl glycerin • Trylagen PCB solution in an amount of 3.00% by weight: active ingredient Pseudoalteromonas ferment extract at 12% by weight, hydrolyzed wheat protein at 3% by weight, hydrolyzed soy protein at 2% by weight, tripeptide-10 citrulline at 2% by weight, tripeptide-1 at 0%, 01% by weight, lecithin, butylene glycol, phenoxyethanol • PhytoCellTec ™ Malus Domestica in an amount of 2.50% by weight: active substance extract from the plant stem cell culture of Malus Domestica in an amount of 9% by weight, • Citrustem ™ water solution in an amount of 2, 50% by weight: water, glycerine, Citrus Aurantium Dulcis (Orange), Callus Culture Extract, xanthan gum (Xanthan Gum), sodium benzoate (Sodium Benzoate), gluconolactone, calcium gluconate (Calcium Gluconate) Sick of 2.00% by weight.

Glycerin in an amount of 2.00 wt.

• Sodium Hyaluronate (Sodium Hyaluronate) in an amount of 1.50 wt.

Ν, Ν-dimethylamino ethanol in an amount of 0.50 wt.

Panthenol in an amount of 0.30 wt.

Carbomer in an amount of 0.60 wt.

Triethanolamine in an amount of 0.60 wt.

Phenoxyethanol, ethylhexyglycerin in an amount of 1.00 wt.

Benzyl alcohol (Benzyl alcohol), 5-chloro-2-methyl-4-isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one in an amount of 0.10 wt.

Polypant Anti-wrinkle solution (water, glycerine, plant extracts: Asiatic Centelia, Horsetail, Hammamelis, Lemon, Hops, Pine, Rosemary, Sage) in an amount of 0.10 wt.

Perfume in an amount of 0.20 wt.

Anti-mimic wrinkle cleaning solution with stem cells cleanses the skin and helps maintain its elasticity and reduce wrinkle depth. Tones and strengthens the skin and gives it radiance at any age.

Example 4 - anti-mimic wrinkle stem cell cleaning solution (composition per 100 g product) Water in an amount of 28.10 wt.

• Paraffin Liquidum in an amount of 28.00 wt.

Argirelin solution in an amount of 10.00% by weight: active substance acetyl hexapeptide-8 in an amount of 0.05% by weight.

Leuphasyl solution in an amount of 6.00% by weight: pentapeptide-18 active ingredient in an amount of 0.05% by weight.

Snap7 solution in an amount of 5.00% by weight: the active substance acetyl-heptapeptide-4 in an amount of 0.05% by weight.

CG-NanoEDP3 solution in an amount of 5.00% by weight: active ingredient oligopeptide-24 in an amount of 0.05% by weight.

• Trylagen PCB solution in an amount of 3.00% by weight: active ingredient Pseudoalteromonas ferment extract in an amount of 12% by weight, hydrolyzed wheat protein in an amount of 3% by weight, hydrolyzed soy protein in an amount of 2% by weight, tripeptide-10 citrulline in 0.04 wt%, tripeptide-1 at 0.01 wt%, Citrustem ™ water solution at 2.50 wt%: water, glycerin, Citrus Aurantium Dulcis (Orange), Callus Culture Extract, xanthan resin (Xanthan Gum), sodium benzoate (Sodium Benzoate), Gluconolactone, calcium gluconate (Calcium Gluconate) • PhytoCellTec ™ Malus Domestica in an amount of 2.50% by weight: active substance extract from the plant stem cell culture Malus Domestica in an amount of 9% by weight Glycerin in an amount of 2.00% by weight.

Isopropyl myristate in an amount of 2.00 wt.

% Sodium hyaluronic acid (Sodium Hyaluronate) in an amount of 1.50 wt.

Phenoxyethanol, ethylhexyglycerin in an amount of 1.00 wt.

Bodyfensine solution (Butylene Glycol, water, Acetil Dipeptide-3-Aminohexanoate) in an amount of 1.00 wt.

Renovage solution (Kapryl / kaprin triglyceride, Teprenon) in an amount of 1.00 wt.

Poloxamer 184 in an amount of 1.00 wt.

Polypant Anti-wrinkle solution (water, glycerine, plant extracts: Asiatic Centelia, Horsetail, Hammamelis, Lemon, Hops, Pine, Rosemary, Sage) in an amount of 0.10 wt.

5-chloro-2-methyl-4-isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one in an amount of 0.10 wt.

Perfume in an amount of 0.20 wt.

Anti-mimic wrinkle cleaning solution with stem cells cleanses the skin and helps maintain its elasticity and reduce wrinkle depth. Tones and strengthens the skin and gives it radiance at any age.

Claims (1)

Cosmetic composition for improving the functional properties of the skin, with plant stem cells and peptides, comprising a combination of the following active ingredients: acetyl hexapeptide-8 in an amount of 0.005% by weight, pentapeptide-18 in an amount of 0.003% by weight, oligopeptide -24 at 0.0025 wt%, tripeptide-10 citrulline at 0.0012 wt%, tripeptide-1 at 0.0003 wt%, acetyl heptapeptide-4 at 0.0025 wt%, extract Pseudoalteromonas v SK 6882 Υ1 0.36% by weight, hydrolyzed wheat protein at 0.09% by weight, hydrolyzed soy protein at 0.06% by weight, extract from Malus Domestica plant stem cell culture at 0.225% by weight, % sodium hyaluronic acid (Sodium Hyaluronate) in an amount of 1.5 wt. and Ν, Ν-dimethylamino ethanol in an amount of 0.5 wt. End of document