SK559188A3 - Printing pad device for transferring specific quantities of printing medium per unit area - Google Patents

Abstract

In the printing pad device described, the surface of the pad (20) is recessed while retaining essentially the same external form and volume. Also described is the use of the pad for at least partially coating a substrate (22) with a predetermined pattern. The substrate (22) is a printed circuit board for manufacturing integrated circuits, a component of a pharmaceutical presentation and/or dosage form, a label with raised characters, a prepolymer or similar.

Description

A tampon printing device for transferring a defined amount of the printing environment to a surface unit

Oblast tečhnikv; .

The invention relates to a tampon printing apparatus for transferring a defined amount of the printing medium to a surface unit, as well as its use.

BACKGROUND OF THE INVENTION

Tampon printing methods have been known since 1968 and are also suitable for suppressing uneven surfaces, with which the flexible tampons carrying the printing environment are adapted. The tampon printing apparatus is described, for example, in DE-OS 19 39 437. The image element to be printed is deeply etched in the printing plate. The printing medium is transferred to this block by spreading, which dispenses the printing medium absorbed by the printing block, the remaining printing medium is perfectly removed from the block by a swab and transferred to the object to be printed. An overview of the use and properties of the tampon printing process can be found in the prospectus of TAMPORINT GmbH, Daimlerstrasse 27/1 in Korntal-Munchingen, which has been taken into consideration in order to avoid full repetition.

Tampon suppression devices are very advantageous because they are low space-consuming because they can be easily integrated into the production line and closed as well, helping to process highly efficient or toxic printing environments such as medicament-etching inks, starters polymerization and the like, to protect the operating personnel, but also to reduce the evaporation rate of the volatiles.

Until now, however, it has not been attempted to use a tamponage printing device to apply precisely controlled amounts of printing environment; surprisingly, it has been shown that by means of the already known tamponage printing process, it is possible to accurately meter the basis weight up to 26 g / cm in the printing process with a variation of ± 2% or less.

In this connection, as described in the co-pending German patent application, the process for the production of a drug delivery and / or dosage form by means of a printing process, with the same filing date, by the applicant can also be applied with highly sensitive drugs or control membranes to the corresponding substrates.

The use of the hitherto known means, namely variations of the tamponizing material (in the case of using softer tampons, more printing medium is transferred) as well as the viscosity of the printing medium could only be applied to the substrate by a slightly increased but still constant amount of printing medium; however, this amount was not sufficient to coat larger basis weights, such as above 100 g / cm @ 2, so the tamponage suppression method, despite its excellent properties, was not suitable for use in producing thicker layers of materials in one predetermined pattern. transfer layers using this method.

Expensive network printing methods or multi-step combination coating methods were used.

Accordingly, it is an essential object of the present invention to provide a further known device to the extent that it is possible to transfer a larger amount of printing medium to the substrate than has been the case with conventional tampons.

SUMMARY OF THE INVENTION

This task has been accomplished by a tampon printing apparatus for transferring a defined amount of printing environment to a surface unit by means of a tampon in which the tampon is provided with a roughening which increases its active surface area and thus exhibits increased capacity for the printing environment while maintaining the same external shape and volume.

The roughening of the surface is formed by a raster, grooving or knobs formed on at least a portion of the surface of the tampon to carry the printing environment.

A tampon printing apparatus is used to at least partially apply a printing environment to substrates in a predetermined pattern, wherein the substrate is a circuit board for manufacturing integrated circuits, part of a pharmaceutical administration and / or dosage form, a label with a bulging sign or a polymer blank.

The surface enlargement is further achieved by treating the finished tampon body or by forming an enlarged tampon surface to shape the tampon body in a suitable form.

Such tampons, in contrast to conventional smooth-surface tampons, are suitable for carrying up to more than three times the amount of printing medium as compared to the amount of medium that could be transferred using the same mold.

By further development of the known tampon printing apparatus according to the invention, it has been made possible for the first time to use these apparatuses or methods in completely new fields of application preferably for the production of coatings. This is the case, for example, in the manufacture of high-color labels, integrated circuits, whereby photo-paints or even conductor material can be suppressed; furthermore, it can be used for the targeted application of polymerization initiators on prepolymers, for the application of etching fluids for the production of etched patterns, for the transfer of paints to porcelain, for the manufacture of pharmaceutical administration and / or dosage forms such as tablets, dermally administrable systems; which carry substances through the mucosa, as in rectal and vaginal forms of use.

It is particularly preferred for use in the manufacture of patch transdermal therapeutic systems.

By means of the invention, the amount of printing medium which is transferred during the printing process can be increased by an unexpected amount and, surprisingly, a constant dosage can be kept within narrow limits.

By means of the device according to the invention, printing media containing the active substance can also be produced in the desired form for the first time in the desired form, as has hitherto been the case with the surface coating methods used hitherto, for example in transdermal therapeutic systems. the expensive active substance is saved and the problematic disposal of the active substance waste is avoided.

Furthermore, it is now possible to apply several printing environments such as multiple dyes, paints and adhesives, glue and a range containing aseptic or active substances and patches simultaneously and spatially distinct from each other in a single manufacturing step using a suitable printing block, thereby saving a single manufacturing step . Plates, as well as tampons, can be tempered if certain adhesives are to be treated with temperature-sensitive materials or even materials that are only heat-treated. It is also possible to cool these and the entire plant when temperature-sensitive materials are to be processed and / or incorporated.

By selecting a suitable tampon material, various requirements can be met, for example, all rubber-elastic materials known to the person skilled in the art, such as natural and synthetic rubber, and in particular silicone rubber, can be selected according to desired properties such as workability, resistance to wear. solvents, heat resistance or sufficient flexibility at low temperatures.

The tampon form can be selected with respect to the substrate to be treated; it is possible to use all conventional forms, such as the truncated cone shape, as well as flat and egg-shaped tampons with an increased suppression surface.

By a printing process, a basis weight of about 200 g per square meter of printing environment and more can be transferred using the apparatus of the present invention.

Overview of the drawings

Further features and advantages of the invention are explained with reference to the accompanying drawing, wherein FIG. 1 a tampon printing apparatus for applying a printing medium to a substrate;

Fig. 2 shows the tampon printing device of FIG. 1 when a new printing environment is taken from a printing block;

Fig. 3 a tampon according to the invention with an increased surface area;

Fig. 4 another swab according to the invention with an increased surface area;

Fig. 5 is a cross-sectional view of a transdermal therapeutic patch system made in accordance with the invention, and FIG. 6 shows a plan view of a further active substance layer with different active substances produced by the tampon printing device according to the invention, and FIG. 7 shows a further advantageous administration form, in particular made by the device according to the invention.

DETAILED DESCRIPTION OF THE INVENTION

In FIG. 1 schematically depicts a deposition of a printing medium layer using a tampon 20 produced according to the invention on a flat substrate 22. In this process, a flexible egg-shaped tampon 20 of silicone rubber is coated with a printing medium coating in the region of the surface area 23 which has been picked up. step of the device from a deepening of the printing plate 24 (see FIG. 2) formed in a tie with the desired pattern of the applied printing medium on a flat substrate on which it leaves a uniform thickness of the printing medium layer after lifting the tampon 20. In the same way, it is possible to suppress uneven substrates, optionally round substrates or corrugated substrates, as well as dishware and the like.

FIG. 3 shows a preferred embodiment of an egg tampon 20 according to the invention, in which areas of the surface 23 that serve to transmit the printing environment are formed by groove-like depressions enlarging the surface 23, by means of which a larger amount of printing environment can be received and transferred. The amount of printing medium absorbed in the process is determined by the etching depth and etching shape of the printing block 24 from which the printing environment is perfectly removed after it has been opened. using a squeegee applied to the block 24 in a uniform thickness and in this form collected and transferred.

In FIG. 4 is another preferred embodiment of the tampon 20, which is substantially cylindrical herein. For the deposition or transfer surface of the tampon 20, knobs are provided for enlarging the surface, which also serve to absorb a greater amount of printing environment.

In FIG. 5 shows an active substance-containing patch which can be produced by the device according to the invention. This can be produced, for example, by uniformly pressing the ribbed, drug-impermeable acrylic self-adhesive layer 16 on the cover film 15, here a siliconized paper which is collected prior to use, as well as circular control layers 18 which control by constant thickness and their chemical-physical passage and, finally, by printing the active substance-containing layer 14 with a printing device according to the invention and laminating with an impermeable layer, here a polyester laminate 10. As a control property of the tamponage following aluminum layer 18, the properties of which are guaranteed only at high thickness , the active ingredient content of which can also be obtained in a pharmaceutically usable suitable form only with large thickness and area constants of the coating, can be applied by the device according to the invention.

In FIG. 6 shows a patch as in FIG. 5 prior to application of the backing layer 10, wherein a plaster with two active substances 14 and 14 is shown. This embodiment is also feasible in a single step of the process of applying the active substance 14, 14 by means of a tamponizing printing device according to the invention, the self-adhesive ring 16 which is clearly visible here is also impermeable to the active substance.

In FIG. 7 is another pharmacological dosage form that can be made by the device of the invention, dragees 30 coated with a sugar sheath having a two-layer core 34. 36. which can be made by printing the layer 36 on a circular support without waste of the substrate material or printed layer.

Other embodiments, combinations, and uses of the device of the invention may be practiced by those skilled in the art, and are within the scope of the invention.

Claims (3)

PATENT CLAIMS A tampon printing apparatus for transferring a defined amount of printing medium to a surface unit by means of a tampon (20), characterized in that the tampon (20) is provided with a roughening which increases its active surface area and thus has an increased capacity for the printing environment. while maintaining the same external shape and volume. Device according to claim 1, characterized in that the roughening of the surface is formed by a raster, grooving or knobs on at least a portion of the surface of the tampon (20) for transferring the printing medium. Use of a tampon printing apparatus according to claim 1 or 2 for at least partially applying the printing environment to a substrate in a predetermined pattern, wherein the substrate is a circuit board for manufacturing integrated circuits, a pharmaceutical administration and / or dosage form component, a bulging label or a polymer blank. .