SK37594A3 - Method of preparation of antimicrobial quinolonyl lactams - Google Patents
Method of preparation of antimicrobial quinolonyl lactams Download PDFInfo
- Publication number
- SK37594A3 SK37594A3 SK375-94A SK37594A SK37594A3 SK 37594 A3 SK37594 A3 SK 37594A3 SK 37594 A SK37594 A SK 37594A SK 37594 A3 SK37594 A3 SK 37594A3
- Authority
- SK
- Slovakia
- Prior art keywords
- oxo
- carboxylic acid
- hydrogen
- alkyl
- bond
- Prior art date
Links
- 0 C[C@]([C@]([C@@]1SC(COC(N(CC2)C(C)CN2c(c(OC)c(c2c3)N(C4CC4)C=C(*)C2=O)c3F)=O)=C(*)N11)C1=O)O Chemical compound C[C@]([C@]([C@@]1SC(COC(N(CC2)C(C)CN2c(c(OC)c(c2c3)N(C4CC4)C=C(*)C2=O)c3F)=O)=C(*)N11)C1=O)O 0.000 description 4
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76961591A | 1991-10-01 | 1991-10-01 | |
| PCT/US1992/008246 WO1993007154A1 (fr) | 1991-10-01 | 1992-09-28 | Procede pour fabriquer des lactames de quinolonyle antimicrobiens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK37594A3 true SK37594A3 (en) | 1995-02-08 |
Family
ID=25085987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK375-94A SK37594A3 (en) | 1991-10-01 | 1992-09-28 | Method of preparation of antimicrobial quinolonyl lactams |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5281703A (fr) |
| EP (1) | EP0606336B1 (fr) |
| KR (1) | KR100253825B1 (fr) |
| CN (1) | CN1046523C (fr) |
| AT (1) | ATE150463T1 (fr) |
| AU (1) | AU667837B2 (fr) |
| BR (1) | BR9206590A (fr) |
| CA (1) | CA2120493A1 (fr) |
| CZ (1) | CZ73194A3 (fr) |
| DE (1) | DE69218445T2 (fr) |
| DK (1) | DK0606336T3 (fr) |
| ES (1) | ES2101119T3 (fr) |
| FI (1) | FI941490A (fr) |
| GR (1) | GR3023227T3 (fr) |
| HU (1) | HUT67423A (fr) |
| MX (1) | MX9205620A (fr) |
| NO (1) | NO304599B1 (fr) |
| NZ (1) | NZ244557A (fr) |
| PT (1) | PT100920B (fr) |
| RU (1) | RU2130938C1 (fr) |
| SK (1) | SK37594A3 (fr) |
| WO (1) | WO1993007154A1 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5646163A (en) * | 1992-10-30 | 1997-07-08 | The Procter & Gamble Company | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
| DE69433651T2 (de) * | 1993-12-28 | 2004-08-19 | Kao Corp. | Vernetzte Zellulosefasern, absorbierende Papiere und absorbierende Elemente, Deckschicht und absorbierende Gegenstände, wobei diese Fasern Verwendung finden |
| JPH10503521A (ja) * | 1994-08-02 | 1998-03-31 | ザ、プロクター、エンド、ギャンブル、カンパニー | キノロニルラクタム抗微生物剤の製造方法及び新規中間化合物 |
| WO1996004247A1 (fr) * | 1994-08-02 | 1996-02-15 | The Procter & Gamble Company | Procede d'elaboration de composes antimicrobiens |
| US5607928A (en) * | 1994-08-05 | 1997-03-04 | Zeneca Limited | Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives |
| EP0695753A1 (fr) * | 1994-08-05 | 1996-02-07 | Zeneca Limited | Dérivés de carbapénème contenant un substituant bicyclique, procédé pour leur préparation et leur application |
| US5693791A (en) * | 1995-04-11 | 1997-12-02 | Truett; William L. | Antibiotics and process for preparation |
| EP0970065A4 (fr) * | 1997-11-29 | 2001-03-07 | William L Truett | Antibiotiques et leur procede de preparation |
| US6437119B1 (en) | 1998-05-07 | 2002-08-20 | William Lawrence Truett | Compounds formed from two or three antibiotics and their processes of preparation |
| US6947844B2 (en) * | 2000-08-09 | 2005-09-20 | Yale University | Modulators of ribosomal function and identification thereof |
| US6638908B1 (en) * | 2000-08-09 | 2003-10-28 | Yale University | Crystals of the large ribosomal subunit |
| IN191798B (fr) | 2000-11-03 | 2004-01-03 | Ranbaxy Lab Ltd | |
| DE60101724T2 (de) * | 2001-03-30 | 2004-12-02 | Dar Al Dawa Development, And Investment Co. | Chinolin-4-on Derivate und deren Verwendung als Antibiotika |
| IL151012A0 (en) * | 2001-08-03 | 2003-02-12 | Ribosomes Structure And Protei | Ribosomes structure and protein synthesis inhibitors |
| US6952650B2 (en) | 2001-08-03 | 2005-10-04 | Yale University | Modulators of ribosomal function and identification thereof |
| US7091196B2 (en) | 2002-09-26 | 2006-08-15 | Rib-X Pharmaceuticals, Inc. | Bifunctional heterocyclic compounds and methods of making and using same |
| KR20060002800A (ko) * | 2003-03-05 | 2006-01-09 | 립-엑스 파마슈티칼즈, 인크. | 이관능성 헤테로시클릭 화합물, 및 그의 제조 및 사용 방법 |
| EP1682563A1 (fr) * | 2003-10-30 | 2006-07-26 | Rib-X Pharmaceuticals, Inc. | Composes heterocycliques macrolidiques bifonctionnels et leurs procedes de preparation et d'utilisation |
| US20070270357A1 (en) * | 2003-11-18 | 2007-11-22 | Farmer Jay J | Bifunctional Macrolide Heterocyclic Compounds and Methods of Making and Using the Same |
| EP2716647A3 (fr) | 2004-02-27 | 2014-08-20 | Rib-X Pharmaceuticals, Inc. | Composes Macrocycliques Et Leurs Procedes De Fabrication Et D'utilisation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT49889A (en) * | 1988-03-31 | 1989-11-28 | Hoffmann La Roche | Process for producing acyl derivatives |
| EP0366193A3 (fr) * | 1988-10-24 | 1992-01-08 | Norwich Eaton Pharmaceuticals, Inc. | Quinolonyl-lactames antimicrobiennes |
| EP0997466A1 (fr) * | 1988-10-24 | 2000-05-03 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Lactam-quinolones antimicrobiennes |
| ES2148135T3 (es) * | 1988-10-24 | 2000-10-16 | Norwich Eaton Pharma | Nuevos esteres antimicrobianos de quinolonil lactamas. |
| SG54293A1 (en) * | 1988-10-24 | 1998-11-16 | Procter & Gamble Pharma | Novel antimicrobial fluoroquinolonyl cephems |
| ZA912279B (en) * | 1990-04-09 | 1992-02-26 | Hoffmann La Roche | Carbapenem compounds |
| EP0525057B1 (fr) * | 1990-04-18 | 2000-06-14 | Procter & Gamble Pharmaceuticals, Inc. | Quinolonyle lactames anti-microbiens |
-
1992
- 1992-09-28 DK DK92920743.9T patent/DK0606336T3/da active
- 1992-09-28 RU RU94018240A patent/RU2130938C1/ru active
- 1992-09-28 EP EP92920743A patent/EP0606336B1/fr not_active Expired - Lifetime
- 1992-09-28 DE DE69218445T patent/DE69218445T2/de not_active Expired - Fee Related
- 1992-09-28 ES ES92920743T patent/ES2101119T3/es not_active Expired - Lifetime
- 1992-09-28 CZ CS94731A patent/CZ73194A3/cs unknown
- 1992-09-28 CA CA002120493A patent/CA2120493A1/fr not_active Abandoned
- 1992-09-28 SK SK375-94A patent/SK37594A3/sk unknown
- 1992-09-28 HU HU9400940A patent/HUT67423A/hu unknown
- 1992-09-28 KR KR1019940701029A patent/KR100253825B1/ko not_active IP Right Cessation
- 1992-09-28 WO PCT/US1992/008246 patent/WO1993007154A1/fr not_active Application Discontinuation
- 1992-09-28 AU AU26938/92A patent/AU667837B2/en not_active Ceased
- 1992-09-28 BR BR9206590A patent/BR9206590A/pt not_active Application Discontinuation
- 1992-09-28 AT AT92920743T patent/ATE150463T1/de not_active IP Right Cessation
- 1992-09-30 NZ NZ244557A patent/NZ244557A/en unknown
- 1992-09-30 MX MX9205620A patent/MX9205620A/es not_active IP Right Cessation
- 1992-09-30 CN CN92112821A patent/CN1046523C/zh not_active Expired - Fee Related
- 1992-10-01 PT PT100920A patent/PT100920B/pt not_active IP Right Cessation
-
1993
- 1993-05-07 US US08/059,529 patent/US5281703A/en not_active Expired - Fee Related
-
1994
- 1994-03-25 NO NO941108A patent/NO304599B1/no not_active IP Right Cessation
- 1994-03-30 FI FI941490A patent/FI941490A/fi unknown
-
1997
- 1997-04-22 GR GR970400889T patent/GR3023227T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0606336B1 (fr) | 1997-03-19 |
| NO304599B1 (no) | 1999-01-18 |
| PT100920B (pt) | 1999-07-30 |
| CN1046523C (zh) | 1999-11-17 |
| DE69218445T2 (de) | 1997-08-07 |
| ATE150463T1 (de) | 1997-04-15 |
| DE69218445D1 (de) | 1997-04-24 |
| CZ73194A3 (en) | 1994-11-16 |
| FI941490A (fi) | 1994-05-02 |
| DK0606336T3 (da) | 1997-04-14 |
| EP0606336A1 (fr) | 1994-07-20 |
| NO941108L (no) | 1994-05-31 |
| AU667837B2 (en) | 1996-04-18 |
| CN1075146A (zh) | 1993-08-11 |
| HUT67423A (en) | 1995-04-28 |
| PT100920A (pt) | 1993-10-29 |
| ES2101119T3 (es) | 1997-07-01 |
| GR3023227T3 (en) | 1997-07-30 |
| FI941490A0 (fi) | 1994-03-30 |
| HU9400940D0 (en) | 1994-06-28 |
| MX9205620A (es) | 1993-12-01 |
| BR9206590A (pt) | 1995-04-25 |
| NO941108D0 (no) | 1994-03-25 |
| RU2130938C1 (ru) | 1999-05-27 |
| US5281703A (en) | 1994-01-25 |
| AU2693892A (en) | 1993-05-03 |
| NZ244557A (en) | 1996-02-27 |
| KR100253825B1 (ko) | 2000-05-01 |
| CA2120493A1 (fr) | 1993-04-15 |
| WO1993007154A1 (fr) | 1993-04-15 |
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