SK287536B6 - Použitie substituovaných zlúčenín 6-dimetylaminometyl-1-fenyl- cyklohexanónu na terapiu inkontinencie moču - Google Patents

Použitie substituovaných zlúčenín 6-dimetylaminometyl-1-fenyl- cyklohexanónu na terapiu inkontinencie moču Download PDF

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Publication number
SK287536B6
SK287536B6 SK595-2003A SK5952003A SK287536B6 SK 287536 B6 SK287536 B6 SK 287536B6 SK 5952003 A SK5952003 A SK 5952003A SK 287536 B6 SK287536 B6 SK 287536B6
Authority
SK
Slovakia
Prior art keywords
dimethylaminomethyl
cyclohexane
enantiomers
compounds
diastereomers
Prior art date
Application number
SK595-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK5952003A3 (en
Inventor
Thomas Christoph
Elmar Friderichs
Original Assignee
Grnenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grnenthal Gmbh filed Critical Grnenthal Gmbh
Publication of SK5952003A3 publication Critical patent/SK5952003A3/sk
Publication of SK287536B6 publication Critical patent/SK287536B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/06—Anti-spasmodics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK595-2003A 2000-11-30 2001-11-28 Použitie substituovaných zlúčenín 6-dimetylaminometyl-1-fenyl- cyklohexanónu na terapiu inkontinencie moču SK287536B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10059413A DE10059413A1 (de) 2000-11-30 2000-11-30 Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
PCT/EP2001/013917 WO2002043714A2 (de) 2000-11-30 2001-11-28 Verwendung von substituierten 6-dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur therapie der harninkontinenz

Publications (2)

Publication Number Publication Date
SK5952003A3 SK5952003A3 (en) 2003-09-11
SK287536B6 true SK287536B6 (sk) 2011-01-04

Family

ID=7665211

Family Applications (1)

Application Number Title Priority Date Filing Date
SK595-2003A SK287536B6 (sk) 2000-11-30 2001-11-28 Použitie substituovaných zlúčenín 6-dimetylaminometyl-1-fenyl- cyklohexanónu na terapiu inkontinencie moču

Country Status (26)

Country Link
US (2) US20040029878A1 (cs)
EP (1) EP1353660B1 (cs)
JP (1) JP4284065B2 (cs)
KR (1) KR100835874B1 (cs)
CN (1) CN1518444B (cs)
AT (1) ATE315387T1 (cs)
AU (2) AU2368802A (cs)
BR (1) BR0115881A (cs)
CA (1) CA2430282C (cs)
CY (1) CY1105142T1 (cs)
CZ (1) CZ299343B6 (cs)
DE (2) DE10059413A1 (cs)
DK (1) DK1353660T3 (cs)
EC (1) ECSP034632A (cs)
ES (1) ES2256338T3 (cs)
HK (1) HK1061355A1 (cs)
HU (1) HU227927B1 (cs)
IL (2) IL156140A0 (cs)
MX (1) MXPA03004801A (cs)
NO (1) NO333963B1 (cs)
NZ (1) NZ538924A (cs)
PL (1) PL203093B1 (cs)
RU (1) RU2279875C2 (cs)
SK (1) SK287536B6 (cs)
WO (1) WO2002043714A2 (cs)
ZA (1) ZA200304999B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050176790A1 (en) 2001-02-28 2005-08-11 Johannes Bartholomaus Pharmaceutical salts
DE10333835A1 (de) * 2003-07-24 2005-03-10 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol enthaltendes Arzneimittel mit verzögerter Wirkstofffreisetzung
WO2005113486A1 (en) * 2004-05-14 2005-12-01 Janssen Pharmaceutica N.V. Carboxamido opioid compounds
US20060254029A1 (en) * 2005-05-11 2006-11-16 Conrad Swenson Pocket loss prevention device
ES2685837T3 (es) * 2006-08-28 2018-10-11 Merck Sharp & Dohme Corp. Proceso y productos intermedios para la síntesis de derivados de (3-alquil-5-piperidin-1-il-3,3a-dihidropirazolo[1,5-a]pirimidin-7-il)-amino
DE102007022790A1 (de) * 2007-05-11 2008-11-20 Grünenthal GmbH Axomadol zur Schmerzbehandlung bei Arthrose
EP2477960A1 (en) * 2009-09-14 2012-07-25 Grünenthal GmbH Crystalline modifications of 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4371720A (en) * 1980-09-19 1983-02-01 Pfizer Inc. 2-Hydroxy-4-(substituted) phenyl cycloalkanes and derivatives
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
AU6747698A (en) * 1997-04-11 1998-11-11 Nippon Shinyaku Co. Ltd. Remedies for frequent urination and urinary incontinence
PE20010623A1 (es) * 1999-10-05 2001-07-07 Gruenenthal Chemie Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
DE10004926A1 (de) * 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten
US6326404B1 (en) * 2000-02-21 2001-12-04 Gruenenthal Gmbh Use of O-desmethyl-N-mono-desmethyl-tramadol
DE10059411A1 (de) * 2000-11-30 2002-06-13 Gruenenthal Gmbh Verwendung von 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz

Also Published As

Publication number Publication date
HK1061355A1 (en) 2004-09-17
NO20032411L (no) 2003-07-17
US20050065120A1 (en) 2005-03-24
CY1105142T1 (el) 2009-11-04
JP2004524280A (ja) 2004-08-12
BR0115881A (pt) 2004-01-20
HUP0303268A3 (en) 2007-03-28
RU2003117705A (ru) 2005-01-27
NO333963B1 (no) 2013-10-28
CN1518444A (zh) 2004-08-04
KR20030055335A (ko) 2003-07-02
RU2279875C2 (ru) 2006-07-20
US7361690B2 (en) 2008-04-22
SK5952003A3 (en) 2003-09-11
CN1518444B (zh) 2011-12-28
DK1353660T3 (da) 2006-03-06
EP1353660A2 (de) 2003-10-22
MXPA03004801A (es) 2003-09-10
CZ20031390A3 (cs) 2003-08-13
JP4284065B2 (ja) 2009-06-24
HU227927B1 (hu) 2012-06-28
WO2002043714A3 (de) 2003-08-14
CA2430282A1 (en) 2002-06-06
US20040029878A1 (en) 2004-02-12
CZ299343B6 (cs) 2008-06-25
ZA200304999B (en) 2004-08-12
DE10059413A1 (de) 2002-06-20
ECSP034632A (es) 2003-07-25
ATE315387T1 (de) 2006-02-15
NZ538924A (en) 2006-09-29
WO2002043714A2 (de) 2002-06-06
AU2368802A (en) 2002-06-11
PL365517A1 (en) 2005-01-10
IL156140A0 (en) 2003-12-23
HUP0303268A2 (hu) 2004-01-28
KR100835874B1 (ko) 2008-06-09
CA2430282C (en) 2011-04-12
AU2002223688B2 (en) 2006-06-01
DE50108711D1 (de) 2006-04-06
IL156140A (en) 2009-02-11
NO20032411D0 (no) 2003-05-27
EP1353660B1 (de) 2006-01-11
PL203093B1 (pl) 2009-08-31
ES2256338T3 (es) 2006-07-16

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US6841575B2 (en) Use of 1-phenyl-3-dimethylaminopropane compounds for treatment of urinary incontinence
SK287536B6 (sk) Použitie substituovaných zlúčenín 6-dimetylaminometyl-1-fenyl- cyklohexanónu na terapiu inkontinencie moču
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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20151128