SK20696A3 - Manufacturing process of dilthiazem - Google Patents

Manufacturing process of dilthiazem Download PDF

Info

Publication number
SK20696A3
SK20696A3 SK206-96A SK20696A SK20696A3 SK 20696 A3 SK20696 A3 SK 20696A3 SK 20696 A SK20696 A SK 20696A SK 20696 A3 SK20696 A3 SK 20696A3
Authority
SK
Slovakia
Prior art keywords
formula
toluene
mixture
diltiazem
reaction
Prior art date
Application number
SK206-96A
Other languages
English (en)
Slovak (sk)
Inventor
Martti Hytoenen
Original Assignee
Orion Corp Fermion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp Fermion filed Critical Orion Corp Fermion
Publication of SK20696A3 publication Critical patent/SK20696A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
SK206-96A 1995-02-17 1996-02-15 Manufacturing process of dilthiazem SK20696A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI950719A FI97725C (fi) 1995-02-17 1995-02-17 Menetelmä diltiatseemin valmistamiseksi

Publications (1)

Publication Number Publication Date
SK20696A3 true SK20696A3 (en) 1997-05-07

Family

ID=8542879

Family Applications (1)

Application Number Title Priority Date Filing Date
SK206-96A SK20696A3 (en) 1995-02-17 1996-02-15 Manufacturing process of dilthiazem

Country Status (18)

Country Link
US (1) US5644054A (fr)
EP (1) EP0728751A3 (fr)
JP (1) JPH08253464A (fr)
BA (1) BA96073A (fr)
CA (1) CA2169717A1 (fr)
CZ (1) CZ287706B6 (fr)
EE (1) EE9600007A (fr)
FI (1) FI97725C (fr)
HR (1) HRP960079A2 (fr)
HU (1) HU218609B (fr)
IL (1) IL117084A (fr)
LV (1) LV11466B (fr)
PL (1) PL312826A1 (fr)
RU (1) RU2139853C1 (fr)
SI (1) SI9600051A (fr)
SK (1) SK20696A3 (fr)
YU (1) YU8996A (fr)
ZA (1) ZA961120B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2445495C1 (ru) * 2011-03-24 2012-03-20 Владимир Викторович Черниченко Способ подачи компонентов топлива в камеру жидкостного ракетного двигателя
FR3033701B1 (fr) 2015-03-19 2021-01-15 Univ Claude Bernard Lyon Nouvelles compositions antivirales pour le traitement de la grippe
RU2628143C1 (ru) * 2016-10-03 2017-08-15 федеральное государственное автономное образовательное учреждение высшего образования "Самарский национальный исследовательский университет имени академика С.П. Королева" Ракетный двигатель малой тяги на газообразных водороде и кислороде с центробежными форсунками

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3582257A (en) * 1968-05-10 1971-06-01 Monsanto Co Soil and stain resistance and soil and stain release properties in textile articles
JPS5899471A (ja) * 1981-12-07 1983-06-13 Tanabe Seiyaku Co Ltd ベンゾチアゼピン誘導体の新規製造法
SE449611B (sv) * 1982-07-09 1987-05-11 Tanabe Seiyaku Co Sett att framstella 1,5-bensotiazepinderivat
US4908469A (en) * 1988-05-18 1990-03-13 Marion Laboratories, Inc. 2-Hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines
US5002942A (en) * 1988-07-25 1991-03-26 Sankyo Company, Limited 1,5-benzothiazepine derivatives, their preparation and their use in the treatment of cardiovascular disorders
IT1244878B (it) * 1990-12-11 1994-09-12 Lusochimica Spa Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato
IT1255545B (it) * 1992-10-23 1995-11-09 Procedimento per la preparazione di diltiazem
FI93741C (fi) * 1993-03-24 1995-05-26 Orion Yhtymae Oy Menetelmä optisesti puhtaitten (2S,3S)- ja (2R,3R)-threo-alkyyli-2-hydroksi-3-(4-metoksifenyyli)-3-(2-X-fenyylitio)propionaattien tai vastaavien asyloitujen yhdisteiden valmistamiseksi

Also Published As

Publication number Publication date
ZA961120B (en) 1996-08-20
US5644054A (en) 1997-07-01
RU2139853C1 (ru) 1999-10-20
JPH08253464A (ja) 1996-10-01
EP0728751A2 (fr) 1996-08-28
HU9600350D0 (en) 1996-04-29
CZ45496A3 (en) 1996-09-11
IL117084A (en) 2001-03-19
FI950719A (fi) 1996-08-18
CZ287706B6 (en) 2001-01-17
SI9600051A (en) 1996-08-31
IL117084A0 (en) 1996-06-18
CA2169717A1 (fr) 1996-08-18
EE9600007A (et) 1996-10-15
FI97725B (fi) 1996-10-31
HU218609B (hu) 2000-10-28
EP0728751A3 (fr) 1996-10-23
FI97725C (fi) 1997-02-10
LV11466B (en) 1996-12-20
FI950719A0 (fi) 1995-02-17
LV11466A (lv) 1996-08-20
BA96073A (bs) 2001-09-14
HRP960079A2 (en) 1997-10-31
PL312826A1 (en) 1996-08-19
YU8996A (sh) 1998-08-14
HUP9600350A1 (en) 1997-04-28

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