SK16497A3 - Macrophage derived chemokine and chemokine analogs - Google Patents
Macrophage derived chemokine and chemokine analogs Download PDFInfo
- Publication number
- SK16497A3 SK16497A3 SK164-97A SK16497A SK16497A3 SK 16497 A3 SK16497 A3 SK 16497A3 SK 16497 A SK16497 A SK 16497A SK 16497 A3 SK16497 A3 SK 16497A3
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- mdc
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- dna
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- 150000003384 small molecules Chemical class 0.000 description 1
- 239000011781 sodium selenite Substances 0.000 description 1
- 235000015921 sodium selenite Nutrition 0.000 description 1
- 229960001471 sodium selenite Drugs 0.000 description 1
- HKHYOKBQJILTEI-UHFFFAOYSA-M sodium;4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1$l^{6}-benzoxathiol-3-yl]phenolate Chemical compound [Na+].C1=CC(O)=CC=C1C1(C=2C=CC([O-])=CC=2)C2=CC=CC=C2S(=O)(=O)O1 HKHYOKBQJILTEI-UHFFFAOYSA-M 0.000 description 1
- 239000008279 sol Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 210000004989 spleen cell Anatomy 0.000 description 1
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- 238000003756 stirring Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- RVUXIPACAZKWHU-UHFFFAOYSA-N sulfuric acid;heptahydrate Chemical compound O.O.O.O.O.O.O.OS(O)(=O)=O RVUXIPACAZKWHU-UHFFFAOYSA-N 0.000 description 1
- KUNICNFETYAKKO-UHFFFAOYSA-N sulfuric acid;pentahydrate Chemical compound O.O.O.O.O.OS(O)(=O)=O KUNICNFETYAKKO-UHFFFAOYSA-N 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 125000005931 tert-butyloxycarbonyl group Chemical group [H]C([H])([H])C(OC(*)=O)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- VUYXVWGKCKTUMF-UHFFFAOYSA-N tetratriacontaethylene glycol monomethyl ether Chemical compound COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO VUYXVWGKCKTUMF-UHFFFAOYSA-N 0.000 description 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
- 238000009210 therapy by ultrasound Methods 0.000 description 1
- 229940071127 thioglycolate Drugs 0.000 description 1
- CWERGRDVMFNCDR-UHFFFAOYSA-M thioglycolate(1-) Chemical compound [O-]C(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-M 0.000 description 1
- 229960003766 thrombin (human) Drugs 0.000 description 1
- 230000003868 tissue accumulation Effects 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 238000007483 tonsillectomy Methods 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 230000003827 upregulation Effects 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 238000003828 vacuum filtration Methods 0.000 description 1
- 108010073969 valyllysine Proteins 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 238000002424 x-ray crystallography Methods 0.000 description 1
- RZLVQBNCHSJZPX-UHFFFAOYSA-L zinc sulfate heptahydrate Chemical compound O.O.O.O.O.O.O.[Zn+2].[O-]S([O-])(=O)=O RZLVQBNCHSJZPX-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/479,620 US6790947B1 (en) | 1995-06-07 | 1995-06-07 | Polynucleotides encoding macrophage derived chemokine |
US55865895A | 1995-11-16 | 1995-11-16 | |
PCT/US1996/010114 WO1996040923A1 (en) | 1995-06-07 | 1996-06-07 | Macrophage derived chemokine and chemokine analogs |
Publications (1)
Publication Number | Publication Date |
---|---|
SK16497A3 true SK16497A3 (en) | 1998-05-06 |
Family
ID=27046294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK164-97A SK16497A3 (en) | 1995-06-07 | 1996-06-07 | Macrophage derived chemokine and chemokine analogs |
Country Status (14)
Country | Link |
---|---|
US (1) | US5932703A (no) |
EP (1) | EP0778892A1 (no) |
JP (1) | JPH10507646A (no) |
AU (1) | AU708743B2 (no) |
BR (1) | BR9606437A (no) |
CA (1) | CA2196691A1 (no) |
CZ (1) | CZ29397A3 (no) |
FI (1) | FI970502A (no) |
HU (1) | HUP9701282A3 (no) |
IL (1) | IL120096A0 (no) |
NO (1) | NO970545L (no) |
PL (1) | PL318594A1 (no) |
SK (1) | SK16497A3 (no) |
WO (1) | WO1996040923A1 (no) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6498015B1 (en) | 1995-06-07 | 2002-12-24 | Icos Corporation | Methods of identifying agents that modulate the binding between MDC and an MDC receptor |
US6737513B1 (en) | 1996-06-07 | 2004-05-18 | Icos Corporation | Macrophage derived chemokine (MDC) and chemokine analogs and assay to identify modulators of MDC activity, and therapeutic uses for same |
US7018627B1 (en) | 1995-06-07 | 2006-03-28 | Icos Corporation | Macrophage derived chemokine (MDC), MDC analogs, MDC inhibitor substances, and uses thereof |
WO1997025427A1 (en) * | 1996-01-12 | 1997-07-17 | Genetics Institute, Inc. | Beta-chemokine, h1305 (mcp-2) |
AU4243097A (en) * | 1996-09-10 | 1998-04-02 | Schering Corporation | Mammalian chemokines, related reagents |
AU7625598A (en) * | 1996-12-03 | 1998-06-29 | Amgen, Inc. | Novel protein with chemokine activity |
JP2001506492A (ja) * | 1996-12-05 | 2001-05-22 | ヒューマン ゲノム サイエンシズ インク. | ヒトケモカインβ−13 |
WO1998042836A1 (en) * | 1997-03-21 | 1998-10-01 | Zymogenetics, Inc. | Mammalian cytokine receptor |
US6548631B1 (en) * | 1997-09-16 | 2003-04-15 | BIOMéRIEUX, INC. | Macrophage derived chemokine (MDC) as an anti-viral agent for the treatment and prevention of lentivirus infection |
AU1815899A (en) * | 1997-12-11 | 1999-06-28 | University Of Maryland Biotechnology Institute | Method and composition to enhance the efficacy of a vaccine using chemokines |
US6093542A (en) * | 1998-01-09 | 2000-07-25 | Akzo Nobel N.V. | Isothermal transcription based amplification assay for the detection and quantitation of macrophage derived chemokine RNA |
US7708983B2 (en) | 1998-12-11 | 2010-05-04 | Alfredo Garzino-Demo | Directional induction of immune response by co-administration of antigens with chemokines |
US7384641B2 (en) | 2000-06-12 | 2008-06-10 | University Of Maryland Biotechnology Institute | Immuno-modulating effects of chemokines in DNA vaccination |
US6488930B1 (en) | 1999-01-15 | 2002-12-03 | Millennium Pharmaceuticals, Inc. | Anti-CCR4 antibodies and methods of use therefor |
US6245332B1 (en) | 1999-01-15 | 2001-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of systemic memory T cell trafficking |
ES2571230T3 (es) | 1999-04-09 | 2016-05-24 | Kyowa Hakko Kirin Co Ltd | Procedimiento para controlar la actividad de una molécula inmunofuncional |
AU2000273378A1 (en) * | 2000-02-18 | 2001-08-27 | Millennium Pharmaceuticals, Inc. | Therapeutic methods that target fractalkine or cx3cr1 |
EP1992644A1 (en) * | 2000-03-03 | 2008-11-19 | Kyowa Hakko Kogyo Co., Ltd | Antibodies against CCR4 and its fragments |
US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
MXPA03004913A (es) * | 2000-12-01 | 2003-09-05 | Schering Corp | Usos de genes de mamifero y reactivos relacionados. |
WO2003084569A1 (fr) | 2002-04-09 | 2003-10-16 | Kyowa Hakko Kogyo Co., Ltd. | Medicament contenant une composition anticorps |
WO2007021807A1 (en) * | 2005-08-12 | 2007-02-22 | Schering Corporation | Mcp1 fusions |
WO2008045461A2 (en) * | 2006-10-11 | 2008-04-17 | Oregon Health & Science University | Transdermal diethylstilbestrol for treating prostate cancer |
US8524217B2 (en) | 2010-05-11 | 2013-09-03 | Merck Sharp & Dohme Corp. | MCP1-Ig fusion variants |
CN116333088A (zh) | 2015-09-16 | 2023-06-27 | Io生物技术公司 | 包含c-c基序趋化因子22(ccl22)或其片段的疫苗组合物 |
US11104727B2 (en) | 2015-10-14 | 2021-08-31 | Nippon Zenyaku Kogyo Co., Ltd. | Anti-canine TARC antibody used for treatment and diagnosis of canine atopic dermatitis |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5037630A (en) * | 1985-01-14 | 1991-08-06 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
US4965392A (en) * | 1987-03-26 | 1990-10-23 | Neorx Corporation | Chelating compounds for metal-radionuclide labeled proteins |
EP0761685A3 (en) * | 1987-10-02 | 1998-01-28 | The Rockefeller University | Macrophage-derived inflammatory mediator (mip-1 alpha and mip-1 beta) |
US5212073A (en) * | 1989-05-12 | 1993-05-18 | Genetics Institute, Inc. | Process for producing human JE cytokine |
US5179078A (en) * | 1989-05-12 | 1993-01-12 | Dana Farber Cancer Institute | Method of suppressing tumor formation in vivo |
US5241049A (en) * | 1989-12-22 | 1993-08-31 | Zymogenetics, Inc. | Neutrophil chemoattractants |
US5413778A (en) * | 1992-10-05 | 1995-05-09 | The Regents Of The University Of Michigan | Labelled monocyte chemoattractant protein material and medical uses thereof |
US5459128A (en) * | 1993-11-12 | 1995-10-17 | Dana-Farber Cancer Institute | Human monocyte chemoattractant protein-1 (MCP-1) derivatives |
CA2179606A1 (en) * | 1993-12-22 | 1995-06-29 | Haodong Li | Macrophage inflammatory proteins-3, -4 and -1.gamma. |
-
1996
- 1996-06-07 CA CA002196691A patent/CA2196691A1/en not_active Abandoned
- 1996-06-07 SK SK164-97A patent/SK16497A3/sk unknown
- 1996-06-07 EP EP96919371A patent/EP0778892A1/en not_active Withdrawn
- 1996-06-07 WO PCT/US1996/010114 patent/WO1996040923A1/en not_active Application Discontinuation
- 1996-06-07 IL IL12009696A patent/IL120096A0/xx unknown
- 1996-06-07 CZ CZ97293A patent/CZ29397A3/cs unknown
- 1996-06-07 US US08/660,542 patent/US5932703A/en not_active Expired - Fee Related
- 1996-06-07 AU AU61724/96A patent/AU708743B2/en not_active Ceased
- 1996-06-07 PL PL96318594A patent/PL318594A1/xx not_active IP Right Cessation
- 1996-06-07 BR BR9606437A patent/BR9606437A/pt not_active Application Discontinuation
- 1996-06-07 JP JP9502209A patent/JPH10507646A/ja not_active Ceased
- 1996-06-07 HU HU9701282A patent/HUP9701282A3/hu unknown
-
1997
- 1997-02-06 FI FI970502A patent/FI970502A/fi not_active Application Discontinuation
- 1997-02-06 NO NO970545A patent/NO970545L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI970502A (fi) | 1997-04-04 |
BR9606437A (pt) | 1997-09-30 |
EP0778892A1 (en) | 1997-06-18 |
US5932703A (en) | 1999-08-03 |
WO1996040923A1 (en) | 1996-12-19 |
HUP9701282A2 (en) | 1997-10-28 |
PL318594A1 (en) | 1997-06-23 |
NO970545D0 (no) | 1997-02-06 |
NO970545L (no) | 1997-04-07 |
JPH10507646A (ja) | 1998-07-28 |
HUP9701282A3 (en) | 1999-09-28 |
FI970502A0 (fi) | 1997-02-06 |
IL120096A0 (en) | 1997-04-15 |
CZ29397A3 (cs) | 1998-01-14 |
AU6172496A (en) | 1996-12-30 |
CA2196691A1 (en) | 1996-12-19 |
AU708743B2 (en) | 1999-08-12 |
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