SK14992000A3 - Spôsob inhibície mrpi - Google Patents

Spôsob inhibície mrpi Download PDF

Info

Publication number
SK14992000A3
SK14992000A3 SK1499-2000A SK14992000A SK14992000A3 SK 14992000 A3 SK14992000 A3 SK 14992000A3 SK 14992000 A SK14992000 A SK 14992000A SK 14992000 A3 SK14992000 A3 SK 14992000A3
Authority
SK
Slovakia
Prior art keywords
phenyl
alkyl
alkoxy
compound
formula
Prior art date
Application number
SK1499-2000A
Other languages
English (en)
Slovak (sk)
Inventor
Joseph Michael Gruber
Bryan Hurst Norman
Sean Patrick Hollinshead
Joseph Wendell Wilson
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of SK14992000A3 publication Critical patent/SK14992000A3/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK1499-2000A 1998-04-08 1999-04-07 Spôsob inhibície mrpi SK14992000A3 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8108898P 1998-04-08 1998-04-08
PCT/US1999/007615 WO1999051236A1 (en) 1998-04-08 1999-04-07 Methods for inhibiting mrp1

Publications (1)

Publication Number Publication Date
SK14992000A3 true SK14992000A3 (sk) 2001-06-11

Family

ID=22162031

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1499-2000A SK14992000A3 (sk) 1998-04-08 1999-04-07 Spôsob inhibície mrpi

Country Status (17)

Country Link
US (1) US6221876B1 (de)
EP (1) EP1067932A4 (de)
JP (1) JP2002510632A (de)
KR (1) KR20010042481A (de)
CN (1) CN1296410A (de)
AU (1) AU3550299A (de)
BR (1) BR9909446A (de)
CA (1) CA2327452A1 (de)
EA (1) EA200001035A1 (de)
HU (1) HUP0102548A2 (de)
ID (1) ID26804A (de)
IL (1) IL138393A0 (de)
NO (1) NO20005041D0 (de)
PL (1) PL343320A1 (de)
SK (1) SK14992000A3 (de)
TR (1) TR200002804T2 (de)
WO (1) WO1999051236A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262098B1 (en) * 1998-08-07 2001-07-17 Chiron Corporation Estrogen receptor modulators
US6743794B2 (en) 1999-12-22 2004-06-01 Eli Lilly And Company Methods and compounds for inhibiting MRP1
ATE282623T1 (de) * 1999-12-22 2004-12-15 Lilly Co Eli Verfahren und verbindungen für die hemmung von mrp1
EP1301518A1 (de) 2000-06-14 2003-04-16 Eli Lilly And Company Tricyclische verbindungen mit mrp1-inhibierender wirkung
CA2442605A1 (en) 2001-04-09 2002-10-17 Mark Christopher Lohman Compounds and methods for inhibiting mrp1
CN1281210C (zh) * 2003-11-29 2006-10-25 胡汛 五味子乙素在制备治疗肿瘤药物中的应用
ATE396725T1 (de) * 2004-05-14 2008-06-15 Cleveland Clinic Foundation Kleinmolekülige hemmer für mrp1 und andere multiarzneimitteltransporter

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182290A (en) * 1991-08-27 1993-01-26 Neurogen Corporation Certain oxazoloquinolinones; a new class of GABA brain receptor ligands

Also Published As

Publication number Publication date
CA2327452A1 (en) 1999-10-14
US6221876B1 (en) 2001-04-24
NO20005041L (no) 2000-10-06
CN1296410A (zh) 2001-05-23
EP1067932A1 (de) 2001-01-17
KR20010042481A (ko) 2001-05-25
EA200001035A1 (ru) 2001-04-23
IL138393A0 (en) 2001-10-31
NO20005041D0 (no) 2000-10-06
TR200002804T2 (tr) 2001-02-21
PL343320A1 (en) 2001-08-13
EP1067932A4 (de) 2001-11-14
HUP0102548A2 (hu) 2001-11-28
AU3550299A (en) 1999-10-25
WO1999051236A1 (en) 1999-10-14
JP2002510632A (ja) 2002-04-09
BR9909446A (pt) 2000-12-12
ID26804A (id) 2001-02-08

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