SK140799A3 - Spiro aminopyrimidines, process for their preparation, pharmaceutical compositions and their use - Google Patents

Spiro aminopyrimidines, process for their preparation, pharmaceutical compositions and their use Download PDF

Info

Publication number
SK140799A3
SK140799A3 SK1407-99A SK140799A SK140799A3 SK 140799 A3 SK140799 A3 SK 140799A3 SK 140799 A SK140799 A SK 140799A SK 140799 A3 SK140799 A3 SK 140799A3
Authority
SK
Slovakia
Prior art keywords
formula
compound
pharmaceutically acceptable
acceptable salt
tautomer
Prior art date
Application number
SK1407-99A
Other languages
English (en)
Slovak (sk)
Inventor
Peter Hamley
Thomas Mcinally
Alan Tinker
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Publication of SK140799A3 publication Critical patent/SK140799A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/20Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1407-99A 1997-04-15 1998-04-07 Spiro aminopyrimidines, process for their preparation, pharmaceutical compositions and their use SK140799A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9701396A SE9701396D0 (sv) 1997-04-15 1997-04-15 Compounds
PCT/SE1998/000642 WO1998046611A1 (en) 1997-04-15 1998-04-07 Compounds

Publications (1)

Publication Number Publication Date
SK140799A3 true SK140799A3 (en) 2000-05-16

Family

ID=20406574

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1407-99A SK140799A3 (en) 1997-04-15 1998-04-07 Spiro aminopyrimidines, process for their preparation, pharmaceutical compositions and their use

Country Status (20)

Country Link
US (1) US6100246A (id)
EP (1) EP0975639A1 (id)
JP (1) JP2001521517A (id)
KR (1) KR20010006349A (id)
CN (1) CN1259132A (id)
AU (1) AU7091198A (id)
BR (1) BR9808546A (id)
CA (1) CA2286789A1 (id)
EE (1) EE9900466A (id)
HU (1) HUP0002245A3 (id)
ID (1) ID23812A (id)
IL (1) IL132272A0 (id)
IS (1) IS5211A (id)
NO (1) NO995007L (id)
NZ (1) NZ338007A (id)
PL (1) PL336318A1 (id)
SE (1) SE9701396D0 (id)
SK (1) SK140799A3 (id)
TR (1) TR199902537T2 (id)
WO (1) WO1998046611A1 (id)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024746A1 (de) * 1998-10-27 2000-05-04 Schering Aktiengesellschaft Thienooxazine als nos-hemmer
US20040009940A1 (en) * 2000-10-20 2004-01-15 Coleman Michael E. Gene delivery formulations and methods for treatment of ischemic conditions
JP4537024B2 (ja) * 2003-08-06 2010-09-01 株式会社琉球バイオリソース開発 炎症疾患予防・治療剤
JO3126B1 (ar) 2007-11-14 2017-09-20 Janssen Pharmaceutica Nv مثبطات ناقل نيوكليوسيد متوازن اي ان تي 1
US20240165148A1 (en) 2021-03-15 2024-05-23 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3686187A (en) * 1970-05-25 1972-08-22 Abbott Lab 4-anilino-1-(4-p-fluorophenyl-1-butyl) piperidine compounds
US4092414A (en) * 1975-04-25 1978-05-30 Merck & Co., Inc. 3,4-Dihydrospiro-2H-1,3-benzoxazines and their use in treating edema, abnormal electrolyte retention, and inflammation
EP0189370A3 (de) * 1985-01-16 1988-01-27 Sandoz Ag Spiro-dioxolane, -dithiolane und -oxothiolane
DE4315625A1 (de) * 1993-05-11 1994-11-17 Hoechst Ag Neue Derivate des 3-Fluorphenols, Verfahren zu ihrer Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
AU7091198A (en) 1998-11-11
EE9900466A (et) 2000-04-17
HUP0002245A3 (en) 2001-06-28
BR9808546A (pt) 2000-05-23
CN1259132A (zh) 2000-07-05
IL132272A0 (en) 2001-03-19
CA2286789A1 (en) 1998-10-22
US6100246A (en) 2000-08-08
JP2001521517A (ja) 2001-11-06
SE9701396D0 (sv) 1997-04-15
WO1998046611A1 (en) 1998-10-22
EP0975639A1 (en) 2000-02-02
NO995007L (no) 1999-12-14
IS5211A (is) 1999-10-12
HUP0002245A2 (hu) 2001-05-28
NZ338007A (en) 2001-05-25
NO995007D0 (no) 1999-10-14
KR20010006349A (ko) 2001-01-26
PL336318A1 (en) 2000-06-19
TR199902537T2 (xx) 2000-02-21
ID23812A (id) 2000-05-11

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