SK128999A3 - Aminopyrimidine derivatives, preparation method thereof, pharmaceutical compositions containing them and their use - Google Patents

Aminopyrimidine derivatives, preparation method thereof, pharmaceutical compositions containing them and their use Download PDF

Info

Publication number
SK128999A3
SK128999A3 SK1289-99A SK128999A SK128999A3 SK 128999 A3 SK128999 A3 SK 128999A3 SK 128999 A SK128999 A SK 128999A SK 128999 A3 SK128999 A3 SK 128999A3
Authority
SK
Slovakia
Prior art keywords
formula
compound
pyrimidine
amino
pyrido
Prior art date
Application number
SK1289-99A
Other languages
English (en)
Slovak (sk)
Inventor
Thomas Mcinally
Alan Tinker
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Publication of SK128999A3 publication Critical patent/SK128999A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK1289-99A 1997-04-09 1998-04-07 Aminopyrimidine derivatives, preparation method thereof, pharmaceutical compositions containing them and their use SK128999A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9701304A SE9701304D0 (sv) 1997-04-09 1997-04-09 Compounds
PCT/SE1998/000641 WO1998045294A1 (en) 1997-04-09 1998-04-07 Compounds

Publications (1)

Publication Number Publication Date
SK128999A3 true SK128999A3 (en) 2000-05-16

Family

ID=20406499

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1289-99A SK128999A3 (en) 1997-04-09 1998-04-07 Aminopyrimidine derivatives, preparation method thereof, pharmaceutical compositions containing them and their use

Country Status (21)

Country Link
US (1) US6303613B1 (tr)
EP (1) EP0973772A1 (tr)
JP (1) JP2001519805A (tr)
KR (1) KR20010006143A (tr)
CN (1) CN1259131A (tr)
AU (1) AU7091098A (tr)
BR (1) BR9807950A (tr)
CA (1) CA2285388A1 (tr)
CZ (1) CZ355199A3 (tr)
EE (1) EE9900448A (tr)
HU (1) HUP0001865A2 (tr)
ID (1) ID23861A (tr)
IL (1) IL132085A0 (tr)
IS (1) IS5208A (tr)
NO (1) NO994900L (tr)
NZ (1) NZ338006A (tr)
PL (1) PL336141A1 (tr)
SE (1) SE9701304D0 (tr)
SK (1) SK128999A3 (tr)
TR (1) TR199902495T2 (tr)
WO (1) WO1998045294A1 (tr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
SE9901530D0 (sv) * 1999-04-28 1999-04-28 Astra Pharma Prod Novel compounds
AU2001282886A1 (en) * 2000-07-13 2002-01-30 Pharmacia Corporation Combination of a cox-2 inhibitor and a vasomodulator for treating pain and headache pain
ES2290157T3 (es) 2000-07-20 2008-02-16 Lauras As Uso de inhibidores de cox-2 como inmunoestimulantes en el tratamiento de vih o sida.
US20040048874A1 (en) * 2001-05-22 2004-03-11 Bardsley Hazel Judith New therapeutic use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine
GB0216027D0 (en) * 2002-07-10 2002-08-21 Arachnova Therapeutics Ltd New therapeutic use
WO2003088958A2 (en) * 2002-04-18 2003-10-30 Pharmacia Corporation Combinations of cox-2 inhibitors and other agents for the treatment of parkinson’s disease
AU2003226379A1 (en) * 2002-04-18 2003-11-03 Pharmacia Corporation Treatment of parkinson's disease with cyclooxygenase-2 (cox 2) inhibitor(s)
AU2003260033A1 (en) * 2002-08-29 2004-03-19 Schering Aktiengesellschaft Methods of treating acute respiratory distress syndrome
EP1558081A4 (en) * 2003-01-13 2006-06-14 Dynogen Pharmaceuticals Inc METHOD OF TREATING FUNCTIONAL INTESTINAL DISORDERS
EP1626961B1 (en) * 2003-05-17 2011-11-02 Korea Research Institute of Bioscience and Biotechnology Novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same
DE102005024012A1 (de) * 2005-05-20 2006-11-23 Grünenthal GmbH Verwendung von 2,5-disubstituierten Thiazol-4-on-Derivaten in Arzneimitteln
TW200738658A (en) 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
JP4850914B2 (ja) * 2005-09-01 2012-01-11 エフ.ホフマン−ラ ロシュ アーゲー P2x3およびp2x2/3モジュレーターとしてのジアミノピリミジン
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
TW200833670A (en) 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
AU2009260899B2 (en) 2008-06-18 2012-02-23 Astrazeneca Ab Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders
CA3209491A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3403152A (en) 1967-03-20 1968-09-24 Ciba Geigy Corp 1-aryl-4-imino-1, 2, 3, 4-tetrahydroquinazolines
US3483205A (en) 1967-12-22 1969-12-09 Ciba Geigy Corp Bicyclic tetrahydropyrimidines
SE9703693D0 (sv) * 1997-10-10 1997-10-10 Astra Pharma Prod Novel combination

Also Published As

Publication number Publication date
ID23861A (id) 2000-05-25
EP0973772A1 (en) 2000-01-26
SE9701304D0 (sv) 1997-04-09
WO1998045294A1 (en) 1998-10-15
AU7091098A (en) 1998-10-30
IL132085A0 (en) 2001-03-19
KR20010006143A (ko) 2001-01-26
EE9900448A (et) 2000-04-17
JP2001519805A (ja) 2001-10-23
NZ338006A (en) 2001-04-27
CN1259131A (zh) 2000-07-05
PL336141A1 (en) 2000-06-05
US6303613B1 (en) 2001-10-16
IS5208A (is) 1999-10-05
BR9807950A (pt) 2000-03-08
TR199902495T2 (tr) 2000-07-21
CZ355199A3 (cs) 2000-03-15
NO994900L (no) 1999-11-19
CA2285388A1 (en) 1998-10-15
NO994900D0 (no) 1999-10-08
MX9909188A (en) 2001-07-01
HUP0001865A2 (hu) 2001-01-29

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