SK118293A3 - Multiple hepatitis b virus surface proteins which form particles - Google Patents

Multiple hepatitis b virus surface proteins which form particles Download PDF

Info

Publication number
SK118293A3
SK118293A3 SK1182-93A SK118293A SK118293A3 SK 118293 A3 SK118293 A3 SK 118293A3 SK 118293 A SK118293 A SK 118293A SK 118293 A3 SK118293 A3 SK 118293A3
Authority
SK
Slovakia
Prior art keywords
protein
hepatitis
yeast
pres2
pres1
Prior art date
Application number
SK1182-93A
Other languages
English (en)
Slovak (sk)
Inventor
Peter J Kniskern
Arpi Hagopian
Pamela Burke
Kathryn R Short
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SK118293A3 publication Critical patent/SK118293A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
SK1182-93A 1991-04-29 1992-04-27 Multiple hepatitis b virus surface proteins which form particles SK118293A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69357591A 1991-04-29 1991-04-29
PCT/US1992/003471 WO1992019740A1 (en) 1991-04-29 1992-04-27 Multiple hepatitis b virus surface proteins which form particles

Publications (1)

Publication Number Publication Date
SK118293A3 true SK118293A3 (en) 1994-03-09

Family

ID=24785226

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1182-93A SK118293A3 (en) 1991-04-29 1992-04-27 Multiple hepatitis b virus surface proteins which form particles

Country Status (19)

Country Link
EP (1) EP0511854A1 (fi)
JP (1) JPH06172392A (fi)
KR (1) KR920019819A (fi)
CN (1) CN1070685A (fi)
AU (1) AU1522792A (fi)
BG (1) BG98188A (fi)
CA (1) CA2067590A1 (fi)
CZ (1) CZ226993A3 (fi)
FI (1) FI934777A (fi)
HU (1) HUT67435A (fi)
IE (1) IE921386A1 (fi)
IL (1) IL101653A0 (fi)
MX (1) MX9202006A (fi)
NO (1) NO933895D0 (fi)
NZ (1) NZ242485A (fi)
SK (1) SK118293A3 (fi)
WO (1) WO1992019740A1 (fi)
YU (1) YU45292A (fi)
ZA (1) ZA923070B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2167304T3 (es) * 1987-06-22 2002-05-16 Medeva Holdings Bv Peptido que contiene el antigeno de superficie de la hepatitis b.
EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
IL101651A0 (en) * 1991-04-29 1992-12-30 Merck & Co Inc Hepatitis b virus surface proteins with reduced host carbohydrate content
EP0533263A3 (en) * 1991-09-20 1994-06-08 Merck & Co Inc A multivalent hepatitis b virus vaccine
EP1111061A1 (en) * 1999-12-20 2001-06-27 Universite Libre De Bruxelles Double selection vector
DE10339927A1 (de) * 2003-08-29 2005-03-24 Rhein Biotech Gesellschaft für neue Biotechnologische Prozesse und Produkte mbH Zusammensetzung zur Prophylaxe/Therapie von HBV-Infektionen und HBV-vermittelten Erkrankungen
KR100836745B1 (ko) * 2007-01-31 2008-06-10 (주)두비엘 Ｈｂｖ 백신 및 그의 제조 방법
JP2010096677A (ja) * 2008-10-17 2010-04-30 Toray Ind Inc 抗体／抗原結合能を有する高感度免疫学測定用ナノ粒子

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI861417A0 (fi) * 1985-04-15 1986-04-01 Endotronics Inc Hepatitis b ytantigen framstaelld med rekombinant-dna-teknik, vaccin, diagnostiskt medel och cellinjer samt foerfaranden foer framstaellning daerav.
JPS63230639A (ja) * 1987-03-19 1988-09-27 Nippon Chem Res Kk 新規なｂ型肝炎ウイルス表面抗原粒子とその製法
EP0288198A3 (en) * 1987-04-20 1989-03-29 Takeda Chemical Industries, Ltd. Production of peptide
EP0314096B1 (en) * 1987-10-29 1994-01-12 Zymogenetics, Inc. Methods of regulating protein glycosylation
EP0328123A1 (en) * 1988-02-09 1989-08-16 Eugene Tech International, Inc. Heterogeneous, pre-S rich hepatitis B surface antigen
NZ229260A (en) * 1988-06-03 1994-02-25 Merck & Co Inc Hepatitis b virus, expression cassette for pre-s domain, host cells and
DE69031556T2 (de) * 1989-07-25 1998-05-14 Smithkline Beecham Biolog Antigene sowie Verfahren zu deren Herstellung
CA2022109A1 (en) * 1989-07-31 1991-02-01 Cheryl A. Schulman Enhanced expression of heterologous proteins in recombinant hosts in a non-growth media

Also Published As

Publication number Publication date
CZ226993A3 (en) 1994-04-13
IE921386A1 (en) 1992-11-04
HU9303066D0 (en) 1994-01-28
NO933895L (no) 1993-10-28
EP0511854A1 (en) 1992-11-04
FI934777A0 (fi) 1993-10-28
NO933895D0 (no) 1993-10-28
ZA923070B (en) 1992-12-30
CA2067590A1 (en) 1992-10-30
BG98188A (en) 1994-06-30
WO1992019740A1 (en) 1992-11-12
HUT67435A (en) 1995-04-28
KR920019819A (ko) 1992-11-20
NZ242485A (en) 1993-11-25
CN1070685A (zh) 1993-04-07
MX9202006A (es) 1992-11-01
YU45292A (sh) 1994-06-10
JPH06172392A (ja) 1994-06-21
FI934777A (fi) 1993-10-28
IL101653A0 (en) 1992-12-30
AU1522792A (en) 1992-11-05

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