SK10062002A3 - Antagonisty faktora uvoľňujúceho kortikotropín - Google Patents
Antagonisty faktora uvoľňujúceho kortikotropín Download PDFInfo
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- SK10062002A3 SK10062002A3 SK1006-2002A SK10062002A SK10062002A3 SK 10062002 A3 SK10062002 A3 SK 10062002A3 SK 10062002 A SK10062002 A SK 10062002A SK 10062002 A3 SK10062002 A3 SK 10062002A3
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- alkyl
- carbon atoms
- cycloalkyl
- methyl
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- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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US17661100P | 2000-01-18 | 2000-01-18 | |
PCT/IB2001/000004 WO2001053263A1 (en) | 2000-01-18 | 2001-01-05 | Corticotropin releasing factor antagonists |
Publications (1)
Publication Number | Publication Date |
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SK10062002A3 true SK10062002A3 (sk) | 2004-05-04 |
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Application Number | Title | Priority Date | Filing Date |
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SK1006-2002A SK10062002A3 (sk) | 2000-01-18 | 2001-01-05 | Antagonisty faktora uvoľňujúceho kortikotropín |
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US (1) | US6833378B2 (es) |
EP (1) | EP1263732A1 (es) |
JP (1) | JP2003520272A (es) |
KR (1) | KR20020063934A (es) |
CN (1) | CN1395566A (es) |
AP (1) | AP2002002583A0 (es) |
AR (1) | AR027221A1 (es) |
AU (1) | AU779995B2 (es) |
BG (1) | BG106853A (es) |
BR (1) | BR0107662A (es) |
CA (1) | CA2397633A1 (es) |
CO (1) | CO5271658A1 (es) |
CR (1) | CR6698A (es) |
CZ (1) | CZ20022390A3 (es) |
EA (2) | EA200300834A1 (es) |
EE (1) | EE200200400A (es) |
GT (1) | GT200100007A (es) |
HN (1) | HN2001000006A (es) |
HR (1) | HRP20020599A2 (es) |
HU (1) | HUP0204272A3 (es) |
IL (1) | IL150632A0 (es) |
IS (1) | IS6445A (es) |
MA (1) | MA26864A1 (es) |
MX (1) | MXPA02007047A (es) |
NO (1) | NO20023424L (es) |
OA (1) | OA12157A (es) |
PA (1) | PA8510001A1 (es) |
PE (1) | PE20011166A1 (es) |
PL (1) | PL357589A1 (es) |
SK (1) | SK10062002A3 (es) |
SV (1) | SV2002000289A (es) |
TN (1) | TNSN01008A1 (es) |
UY (1) | UY26544A1 (es) |
WO (1) | WO2001053263A1 (es) |
YU (1) | YU54402A (es) |
ZA (1) | ZA200205660B (es) |
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US7323469B2 (en) | 2001-08-07 | 2008-01-29 | Novartis Ag | 7H-pyrrolo[2,3-d]pyrimidine derivatives |
GB0119249D0 (en) | 2001-08-07 | 2001-10-03 | Novartis Ag | Organic compounds |
AR040456A1 (es) | 2002-06-27 | 2005-04-06 | Bristol Myers Squibb Co | Piridina n-oxidos 2,4 -disubstituidos utiles como inhibidores de transcriptasa inversa del virus de inmunodeficiencia humana |
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EP1688408A3 (en) * | 2002-08-08 | 2007-08-22 | Amgen, Inc | Vanilloid receptor ligands and their use in treatments |
US8293751B2 (en) | 2003-01-14 | 2012-10-23 | Arena Pharmaceuticals, Inc. | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
ATE359782T1 (de) * | 2003-01-16 | 2007-05-15 | Sb Pharmco Inc | Heteroaryl-substituierte pyrrol(2, 3- b)pyridin- derivate als crf-rezeptor-antagonisten |
GB0308208D0 (en) | 2003-04-09 | 2003-05-14 | Glaxo Group Ltd | Chemical compounds |
US7112585B2 (en) | 2003-04-18 | 2006-09-26 | Bristol-Myers Squibb Company | Pyrimidine derivatives as corticotropin releasing factor inhibitors |
US7030145B2 (en) | 2003-04-18 | 2006-04-18 | Bristol-Myers Squibb Company | Pyridinyl derivatives for the treatment of depression |
AR045047A1 (es) * | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
WO2005007658A2 (en) | 2003-07-14 | 2005-01-27 | Arena Pharmaceuticals, Inc. | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
US20050171095A1 (en) * | 2004-01-06 | 2005-08-04 | Pfizer Inc | Combination of CRF antagonists and 5-HT1B receptor antagonists |
US7557111B2 (en) * | 2004-01-06 | 2009-07-07 | Taisho Pharmaceutical Co., Ltd. | Substituted thieno[3,2-d]pyrimidines as CRF receptor antagonists |
MY139645A (en) | 2004-02-11 | 2009-10-30 | Amgen Inc | Vanilloid receptor ligands and their use in treatments |
EP1745034A1 (en) | 2004-02-11 | 2007-01-24 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
BRPI0510453A (pt) | 2004-04-30 | 2007-10-30 | Warner Lambert Co | composto substituìdos com morfolina para o tratamento de distúrbios do sistema nervoso central |
JP2008500284A (ja) * | 2004-05-12 | 2008-01-10 | ブリストル−マイヤーズ スクイブ カンパニー | 血栓症の治療に有用なp2y1レセプターのウレアアンタゴニスト |
AR051095A1 (es) | 2004-09-20 | 2006-12-20 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso comoinhibidores de la estearoil-coa desaturasa |
WO2006089311A1 (en) | 2005-02-15 | 2006-08-24 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
US8153791B2 (en) | 2005-12-21 | 2012-04-10 | Janssen Pharmaceutica N.V. | Substituted pyrimidinyl oxime kinase inhibitors |
WO2007109783A2 (en) * | 2006-03-23 | 2007-09-27 | Janssen Pharmaceutica, N.V. | Substituted pyrimidine kinase inhibitors |
KR101181194B1 (ko) | 2006-10-18 | 2012-09-18 | 화이자 프로덕츠 인코포레이티드 | 바이아릴 에터 우레아 화합물 |
WO2009144632A1 (en) * | 2008-05-30 | 2009-12-03 | Pfizer Limited | Novel compounds |
GB0913636D0 (en) * | 2009-08-05 | 2009-09-16 | Univ Leuven Kath | Novel viral replication inhibitors |
BR112013008100A2 (pt) | 2010-09-22 | 2016-08-09 | Arena Pharm Inc | "moduladores do receptor de gpr19 e o tratamento de distúrbios relacionados a eles." |
WO2014207601A1 (en) | 2013-06-27 | 2014-12-31 | Pfizer Inc. | Heteroaromatic compounds and their use as dopamine d1 ligands |
CN116850181A (zh) | 2015-01-06 | 2023-10-10 | 艾尼纳制药公司 | 治疗与s1p1受体有关的病症的方法 |
ES2872553T3 (es) | 2015-03-06 | 2021-11-02 | Pharmakea Inc | Inhibidores de lisil oxidasa tipo-2 y usos de los mismos |
CA2977947A1 (en) | 2015-03-06 | 2016-09-15 | Pharmakea, Inc. | Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof |
MX2017016530A (es) | 2015-06-22 | 2018-03-12 | Arena Pharm Inc | Sal cristalina de l-arginina del acido (r)-2-(7-(4-ciclopentil-3-( trifluorometil)benciloxi)-1,2,3,4-tetrahidrociclopenta[b]indol-3- il)acetico (compuesto1) para ser utilizada en transtornos asociados con el receptor de esfingosina-1-fosfato 1 (s1p1). |
JP6975514B2 (ja) * | 2016-07-08 | 2021-12-01 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 縮合ピリミジン誘導体 |
JP7187037B2 (ja) * | 2016-09-07 | 2022-12-12 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | p-タウを減少させ、認知機能を改善させるアロステリック副腎皮質刺激ホルモン放出因子受容体1(CRFR1)アンタゴニスト |
BR112019004517A2 (pt) | 2016-09-07 | 2019-08-13 | Pharmakea Inc | formas cristalinas de um inibidor lisil-oxidase-semelhante 2 e métodos de preparação |
EP4052707A1 (en) | 2016-09-07 | 2022-09-07 | Pharmakea, Inc. | Uses of a lysyl oxidase-like 2 inhibitor |
CN110520124A (zh) | 2017-02-16 | 2019-11-29 | 艾尼纳制药公司 | 用于治疗原发性胆汁性胆管炎的化合物和方法 |
PT3609868T (pt) | 2017-03-13 | 2023-12-18 | Raqualia Pharma Inc | Derivados de tetra-hidroquinolina como antagonistas do recetor p2x7 |
US20220125762A1 (en) * | 2019-02-13 | 2022-04-28 | The University Of Vermont And State Agricultural College | Small molecule antagonist to pacap receptor and uses thereof |
JP7493835B2 (ja) * | 2019-11-06 | 2024-06-03 | アルベルト・アインシュタイン・カレッジ・オブ・メディシン | 小分子プロスタグラジン輸送阻害剤 |
WO2024086061A2 (en) * | 2022-10-18 | 2024-04-25 | Merck Sharp & Dohme Llc | Novel kv3 channel modulators |
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PA8467401A1 (es) * | 1998-02-17 | 2000-09-29 | Pfizer Prod Inc | Procedimiento para tratar la insuficiencia cardiaca |
US6130188A (en) * | 1998-05-05 | 2000-10-10 | American Cyanamid Company | Herbicidal pyridine compounds |
EP1040831A3 (en) * | 1999-04-02 | 2003-05-02 | Pfizer Products Inc. | Use of corticotropin releasing factor (CRF) antagonists to prevent sudden death |
US6387894B1 (en) * | 1999-06-11 | 2002-05-14 | Pfizer Inc. | Use of CRF antagonists and renin-angiotensin system inhibitors |
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2001
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- 2001-01-05 YU YU54402A patent/YU54402A/sh unknown
- 2001-01-05 WO PCT/IB2001/000004 patent/WO2001053263A1/en not_active Application Discontinuation
- 2001-01-05 CN CN01803846A patent/CN1395566A/zh active Pending
- 2001-01-05 IL IL15063201A patent/IL150632A0/xx unknown
- 2001-01-05 AP APAP/P/2002/002583A patent/AP2002002583A0/en unknown
- 2001-01-05 OA OA1200200206A patent/OA12157A/en unknown
- 2001-01-05 CA CA002397633A patent/CA2397633A1/en not_active Abandoned
- 2001-01-05 KR KR1020027009229A patent/KR20020063934A/ko not_active Application Discontinuation
- 2001-01-05 EA EA200300834A patent/EA200300834A1/ru unknown
- 2001-01-05 EP EP01900209A patent/EP1263732A1/en not_active Withdrawn
- 2001-01-05 AU AU23905/01A patent/AU779995B2/en not_active Ceased
- 2001-01-05 PL PL01357589A patent/PL357589A1/xx not_active Application Discontinuation
- 2001-01-05 CZ CZ20022390A patent/CZ20022390A3/cs unknown
- 2001-01-05 MX MXPA02007047A patent/MXPA02007047A/es unknown
- 2001-01-05 JP JP2001553267A patent/JP2003520272A/ja active Pending
- 2001-01-05 EA EA200200688A patent/EA200200688A1/ru unknown
- 2001-01-05 EE EEP200200400A patent/EE200200400A/xx unknown
- 2001-01-05 SK SK1006-2002A patent/SK10062002A3/sk unknown
- 2001-01-05 HU HU0204272A patent/HUP0204272A3/hu unknown
- 2001-01-12 HN HN2001000006A patent/HN2001000006A/es unknown
- 2001-01-16 AR ARP010100176A patent/AR027221A1/es not_active Application Discontinuation
- 2001-01-16 PE PE2001000038A patent/PE20011166A1/es not_active Application Discontinuation
- 2001-01-17 TN TNTNSN01008A patent/TNSN01008A1/fr unknown
- 2001-01-17 CO CO01003117A patent/CO5271658A1/es not_active Application Discontinuation
- 2001-01-17 US US09/761,995 patent/US6833378B2/en not_active Expired - Fee Related
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2002
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- 2002-07-11 MA MA26728A patent/MA26864A1/fr unknown
- 2002-07-16 ZA ZA200205660A patent/ZA200205660B/en unknown
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- 2002-07-17 HR HR20020599A patent/HRP20020599A2/hr not_active Application Discontinuation
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