SI3972603T1 - Postopki zdravljenja sjogrenovega sindroma z uporabo zaviralca brutonove tirozin kinaze - Google Patents

Postopki zdravljenja sjogrenovega sindroma z uporabo zaviralca brutonove tirozin kinaze

Info

Publication number
SI3972603T1
SI3972603T1 SI202030536T SI202030536T SI3972603T1 SI 3972603 T1 SI3972603 T1 SI 3972603T1 SI 202030536 T SI202030536 T SI 202030536T SI 202030536 T SI202030536 T SI 202030536T SI 3972603 T1 SI3972603 T1 SI 3972603T1
Authority
SI
Slovenia
Prior art keywords
bruton
syndrome
methods
tyrosine kinase
kinase inhibitor
Prior art date
Application number
SI202030536T
Other languages
English (en)
Slovenian (sl)
Inventor
Souvik Bhattacharya
Bruno Bieth
Maciej Cabanski
Bruno Cenni
Buck Stefan De
Martin Kaul
Arvind Kinhikar
Andrijana Radivojevic
Garami Alessandra Vitaliti
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SI3972603T1 publication Critical patent/SI3972603T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI202030536T 2019-05-23 2020-05-20 Postopki zdravljenja sjogrenovega sindroma z uporabo zaviralca brutonove tirozin kinaze SI3972603T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962851994P 2019-05-23 2019-05-23
EP20729203.8A EP3972603B1 (en) 2019-05-23 2020-05-20 Methods of treating sjögren's syndrome using a bruton's tyrosine kinase inhibitor
PCT/IB2020/054754 WO2020234781A1 (en) 2019-05-23 2020-05-20 Methods of treating sjögren's syndrome using a bruton's tyrosine kinase inhibitor

Publications (1)

Publication Number Publication Date
SI3972603T1 true SI3972603T1 (sl) 2025-02-28

Family

ID=70918750

Family Applications (1)

Application Number Title Priority Date Filing Date
SI202030536T SI3972603T1 (sl) 2019-05-23 2020-05-20 Postopki zdravljenja sjogrenovega sindroma z uporabo zaviralca brutonove tirozin kinaze

Country Status (23)

Country Link
US (2) US12383556B2 (https=)
EP (2) EP3972603B1 (https=)
JP (2) JP7765970B2 (https=)
KR (1) KR20220011652A (https=)
CN (1) CN113811301A (https=)
AU (2) AU2020278236C1 (https=)
BR (1) BR112021023110A2 (https=)
CA (1) CA3137271A1 (https=)
CL (1) CL2021003034A1 (https=)
DK (1) DK3972603T3 (https=)
ES (1) ES3004516T3 (https=)
FI (1) FI3972603T3 (https=)
HR (1) HRP20241584T1 (https=)
HU (1) HUE069020T2 (https=)
IL (1) IL287745B2 (https=)
LT (1) LT3972603T (https=)
MX (1) MX2021014161A (https=)
PL (1) PL3972603T3 (https=)
PT (1) PT3972603T (https=)
RS (1) RS66195B1 (https=)
SI (1) SI3972603T1 (https=)
TW (1) TWI857060B (https=)
WO (1) WO2020234781A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021023110A2 (pt) 2019-05-23 2022-04-12 Novartis Ag Métodos de tratamento de síndrome de sjögren com o uso de um inibidor de tirosina quinase de bruton
MX2023008671A (es) * 2021-01-26 2023-09-25 Novartis Ag Composicion farmaceutica.
CN116782888A (zh) * 2021-01-26 2023-09-19 诺华股份有限公司 药物组合物
JP7564347B2 (ja) 2021-09-03 2024-10-08 ノバルティス アーゲー 多発性硬化症を治療するためのlou064
US20250032488A1 (en) 2021-12-14 2025-01-30 Novartis Ag Methods of treatment using lou064
TW202342048A (zh) 2022-02-28 2023-11-01 瑞士商諾華公司 使用lou064治療化膿性汗腺炎之方法
KR102875105B1 (ko) 2023-04-03 2025-10-21 주식회사 사이알바이오 재조합 세마포린 4d 차단항체를 유효성분으로 포함하는 쇼그렌 증후군 예방 또는 치료용 약학 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ532310A (en) 2001-10-05 2007-02-23 Combinatorx Inc Combinations comprising a tetra-substituted pyrimidopyrimidine and a corticosteroid for the treatment of immunoinflammatory disorders
US9512084B2 (en) 2013-11-29 2016-12-06 Novartis Ag Amino pyrimidine derivatives
LT3390390T (lt) 2015-12-16 2021-11-25 Boehringer Ingelheim International Gmbh Bipirazolilo dariniai, tinkami naudoti autoimuninių ligų gydymui
US10570118B2 (en) 2016-01-13 2020-02-25 Boehringer Ingelheim International Gmbh Isoquinolones as BTK inhibitors
US10874741B2 (en) 2017-08-28 2020-12-29 Spectrix Therapeutics, LLC Compound to treat Sjogren's syndrome
KR20200074993A (ko) 2017-11-03 2020-06-25 노파르티스 아게 쇼그렌 증후군 치료에 사용하기 위한 항-cd40 항체
TWI694995B (zh) * 2017-11-06 2020-06-01 美商美國禮來大藥廠 Btk抑制劑化合物
BR112021023110A2 (pt) 2019-05-23 2022-04-12 Novartis Ag Métodos de tratamento de síndrome de sjögren com o uso de um inibidor de tirosina quinase de bruton

Also Published As

Publication number Publication date
IL287745B1 (en) 2025-10-01
JP2025165957A (ja) 2025-11-05
IL287745B2 (en) 2026-02-01
TWI857060B (zh) 2024-10-01
EP3972603B1 (en) 2024-09-04
EP4442321A2 (en) 2024-10-09
AU2020278236A8 (en) 2022-04-28
AU2025263830A1 (en) 2025-11-27
US12383556B2 (en) 2025-08-12
ES3004516T3 (en) 2025-03-12
CN113811301A (zh) 2021-12-17
EP3972603A1 (en) 2022-03-30
EP4442321A3 (en) 2025-01-01
AU2020278236C1 (en) 2026-02-26
AU2020278236B2 (en) 2025-08-07
RS66195B1 (sr) 2024-12-31
TW202110451A (zh) 2021-03-16
DK3972603T3 (da) 2024-12-02
US20220175772A1 (en) 2022-06-09
WO2020234781A1 (en) 2020-11-26
JP7765970B2 (ja) 2025-11-07
BR112021023110A2 (pt) 2022-04-12
LT3972603T (lt) 2024-12-10
PL3972603T3 (pl) 2025-02-03
FI3972603T3 (fi) 2024-12-04
CL2021003034A1 (es) 2022-09-09
PT3972603T (pt) 2024-11-26
US20250339428A1 (en) 2025-11-06
HRP20241584T1 (hr) 2025-01-31
HUE069020T2 (hu) 2025-02-28
JP2022533968A (ja) 2022-07-27
MX2021014161A (es) 2022-01-04
KR20220011652A (ko) 2022-01-28
AU2020278236A1 (en) 2022-01-06
CA3137271A1 (en) 2020-11-26
IL287745A (en) 2021-12-01

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