HUE069020T2 - Eljárások Sjögren-szindróma kezelésére Bruton-féle tirozinkináz gátlószerének alkalmazásával - Google Patents

Eljárások Sjögren-szindróma kezelésére Bruton-féle tirozinkináz gátlószerének alkalmazásával

Info

Publication number
HUE069020T2
HUE069020T2 HUE20729203A HUE20729203A HUE069020T2 HU E069020 T2 HUE069020 T2 HU E069020T2 HU E20729203 A HUE20729203 A HU E20729203A HU E20729203 A HUE20729203 A HU E20729203A HU E069020 T2 HUE069020 T2 HU E069020T2
Authority
HU
Hungary
Prior art keywords
bruton
syndrome
methods
tyrosine kinase
kinase inhibitor
Prior art date
Application number
HUE20729203A
Other languages
English (en)
Hungarian (hu)
Inventor
Souvik Bhattacharya
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HUE069020T2 publication Critical patent/HUE069020T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HUE20729203A 2019-05-23 2020-05-20 Eljárások Sjögren-szindróma kezelésére Bruton-féle tirozinkináz gátlószerének alkalmazásával HUE069020T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962851994P 2019-05-23 2019-05-23

Publications (1)

Publication Number Publication Date
HUE069020T2 true HUE069020T2 (hu) 2025-02-28

Family

ID=70918750

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE20729203A HUE069020T2 (hu) 2019-05-23 2020-05-20 Eljárások Sjögren-szindróma kezelésére Bruton-féle tirozinkináz gátlószerének alkalmazásával

Country Status (23)

Country Link
US (2) US12383556B2 (https=)
EP (2) EP3972603B1 (https=)
JP (2) JP7765970B2 (https=)
KR (1) KR20220011652A (https=)
CN (1) CN113811301A (https=)
AU (2) AU2020278236C1 (https=)
BR (1) BR112021023110A2 (https=)
CA (1) CA3137271A1 (https=)
CL (1) CL2021003034A1 (https=)
DK (1) DK3972603T3 (https=)
ES (1) ES3004516T3 (https=)
FI (1) FI3972603T3 (https=)
HR (1) HRP20241584T1 (https=)
HU (1) HUE069020T2 (https=)
IL (1) IL287745B2 (https=)
LT (1) LT3972603T (https=)
MX (1) MX2021014161A (https=)
PL (1) PL3972603T3 (https=)
PT (1) PT3972603T (https=)
RS (1) RS66195B1 (https=)
SI (1) SI3972603T1 (https=)
TW (1) TWI857060B (https=)
WO (1) WO2020234781A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021023110A2 (pt) 2019-05-23 2022-04-12 Novartis Ag Métodos de tratamento de síndrome de sjögren com o uso de um inibidor de tirosina quinase de bruton
MX2023008671A (es) * 2021-01-26 2023-09-25 Novartis Ag Composicion farmaceutica.
CN116782888A (zh) * 2021-01-26 2023-09-19 诺华股份有限公司 药物组合物
JP7564347B2 (ja) 2021-09-03 2024-10-08 ノバルティス アーゲー 多発性硬化症を治療するためのlou064
US20250032488A1 (en) 2021-12-14 2025-01-30 Novartis Ag Methods of treatment using lou064
TW202342048A (zh) 2022-02-28 2023-11-01 瑞士商諾華公司 使用lou064治療化膿性汗腺炎之方法
KR102875105B1 (ko) 2023-04-03 2025-10-21 주식회사 사이알바이오 재조합 세마포린 4d 차단항체를 유효성분으로 포함하는 쇼그렌 증후군 예방 또는 치료용 약학 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ532310A (en) 2001-10-05 2007-02-23 Combinatorx Inc Combinations comprising a tetra-substituted pyrimidopyrimidine and a corticosteroid for the treatment of immunoinflammatory disorders
US9512084B2 (en) 2013-11-29 2016-12-06 Novartis Ag Amino pyrimidine derivatives
LT3390390T (lt) 2015-12-16 2021-11-25 Boehringer Ingelheim International Gmbh Bipirazolilo dariniai, tinkami naudoti autoimuninių ligų gydymui
US10570118B2 (en) 2016-01-13 2020-02-25 Boehringer Ingelheim International Gmbh Isoquinolones as BTK inhibitors
US10874741B2 (en) 2017-08-28 2020-12-29 Spectrix Therapeutics, LLC Compound to treat Sjogren's syndrome
KR20200074993A (ko) 2017-11-03 2020-06-25 노파르티스 아게 쇼그렌 증후군 치료에 사용하기 위한 항-cd40 항체
TWI694995B (zh) * 2017-11-06 2020-06-01 美商美國禮來大藥廠 Btk抑制劑化合物
BR112021023110A2 (pt) 2019-05-23 2022-04-12 Novartis Ag Métodos de tratamento de síndrome de sjögren com o uso de um inibidor de tirosina quinase de bruton

Also Published As

Publication number Publication date
IL287745B1 (en) 2025-10-01
JP2025165957A (ja) 2025-11-05
IL287745B2 (en) 2026-02-01
TWI857060B (zh) 2024-10-01
EP3972603B1 (en) 2024-09-04
EP4442321A2 (en) 2024-10-09
AU2020278236A8 (en) 2022-04-28
AU2025263830A1 (en) 2025-11-27
US12383556B2 (en) 2025-08-12
ES3004516T3 (en) 2025-03-12
CN113811301A (zh) 2021-12-17
EP3972603A1 (en) 2022-03-30
EP4442321A3 (en) 2025-01-01
AU2020278236C1 (en) 2026-02-26
AU2020278236B2 (en) 2025-08-07
RS66195B1 (sr) 2024-12-31
TW202110451A (zh) 2021-03-16
DK3972603T3 (da) 2024-12-02
US20220175772A1 (en) 2022-06-09
WO2020234781A1 (en) 2020-11-26
JP7765970B2 (ja) 2025-11-07
BR112021023110A2 (pt) 2022-04-12
LT3972603T (lt) 2024-12-10
PL3972603T3 (pl) 2025-02-03
FI3972603T3 (fi) 2024-12-04
CL2021003034A1 (es) 2022-09-09
PT3972603T (pt) 2024-11-26
US20250339428A1 (en) 2025-11-06
SI3972603T1 (sl) 2025-02-28
HRP20241584T1 (hr) 2025-01-31
JP2022533968A (ja) 2022-07-27
MX2021014161A (es) 2022-01-04
KR20220011652A (ko) 2022-01-28
AU2020278236A1 (en) 2022-01-06
CA3137271A1 (en) 2020-11-26
IL287745A (en) 2021-12-01

Similar Documents

Publication Publication Date Title
PL3972603T3 (pl) Sposoby leczenia zespołu sjögrena przy użyciu inhibitora kinazy tyrozynowej brutona
ZA201903932B (en) Imidazopyrazine inhibitors of bruton's tyrosine kinase
IL255831A (en) Inhibitors of bruton's tyrosine kinase
RS67141B1 (sr) Inhibitor brutonove tirozin kinaze za upotrebu u lečenju hronične spontane urtikarije
IL274716A (en) Synthesis of a proton tyrosine kinase inhibitor
ZA201805439B (en) Bruton's tyrosine kinase inhibitors
IL261249B1 (en) Dosage preparations containing Bruton's tyrosine kinase inhibitor
ZA201903694B (en) Inhibitors of bruton's tyrosine kinase
ZA201906887B (en) Bruton's tyrosine kinase inhibitors
IL259862B (en) Inhibitors of proton tyrosine kinase and methods of using them
EP3273961A4 (en) Solvated forms of a bruton's tyrosine kinase inhibitor
IL284916A (en) Cyclic molecules as Bruton's tyrosine kinase inhibitors
IL285136A (en) bay1895344 kinase atr inhibitor for use in the treatment of hyperproliferative disease
ZA202102274B (en) Use of casein kinase 1 inhibitors for treating vascular diseases
ZA202202617B (en) Treatment of cancer using a combination comprising multi-tyrosine kinase inhibitor and immune checkpoint inhibitor
KR102668958B9 (ko) 브루톤 티로신 키나아제 억제제인 치환된 1-아미노-1h-이미다졸-5-카르복사미드
IL292596A (en) Use of Janus kinase inhibitor and telomerase inhibitor to treat myeloproliferative tumor
PL3846788T3 (pl) Inhibitory pde11 do zastosowania w leczeniu choroby parkinsona
EP4069689A4 (en) SUBSTITUTED IMIDAZOLECARBOXAMIDE AS BRUTON TYROSINKINASE INHIBITORS
MA55964A (fr) Agents inhibiteurs de la tyrosine kinase de bruton
EP3811942A4 (en) USE OF TYROSINE HYDROXYLASE INHIBITORS FOR THE TREATMENT OF AORTIC ANEURYSM
HK40072430A (en) Dosing of a bruton's tyrosine kinase inhibitor
HK40019173A (en) Inhibitors of bruton's tyrosine kinase
HK40080320A (en) Use of a janus kinase inhibitor and a telomerase inhibitor for the treatment of myeloproliferative neoplasms
HK1260107A1 (en) Imidazopyrazine inhibitors of bruton's tyrosine kinase