PL3972603T3 - Sposoby leczenia zespołu sjögrena przy użyciu inhibitora kinazy tyrozynowej brutona - Google Patents

Sposoby leczenia zespołu sjögrena przy użyciu inhibitora kinazy tyrozynowej brutona

Info

Publication number
PL3972603T3
PL3972603T3 PL20729203.8T PL20729203T PL3972603T3 PL 3972603 T3 PL3972603 T3 PL 3972603T3 PL 20729203 T PL20729203 T PL 20729203T PL 3972603 T3 PL3972603 T3 PL 3972603T3
Authority
PL
Poland
Prior art keywords
bruton
syndrome
methods
tyrosine kinase
kinase inhibitor
Prior art date
Application number
PL20729203.8T
Other languages
English (en)
Inventor
Souvik Bhattacharya
Bruno BIETH
Maciej CABANSKI
Bruno CENNI
Stefan De Buck
Martin Kaul
Arvind Kinhikar
Andrijana RADIVOJEVIC
Alessandra VITALITI GARAMI
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL3972603T3 publication Critical patent/PL3972603T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL20729203.8T 2019-05-23 2020-05-20 Sposoby leczenia zespołu sjögrena przy użyciu inhibitora kinazy tyrozynowej brutona PL3972603T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962851994P 2019-05-23 2019-05-23
PCT/IB2020/054754 WO2020234781A1 (en) 2019-05-23 2020-05-20 Methods of treating sjögren's syndrome using a bruton's tyrosine kinase inhibitor

Publications (1)

Publication Number Publication Date
PL3972603T3 true PL3972603T3 (pl) 2025-02-03

Family

ID=70918750

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20729203.8T PL3972603T3 (pl) 2019-05-23 2020-05-20 Sposoby leczenia zespołu sjögrena przy użyciu inhibitora kinazy tyrozynowej brutona

Country Status (23)

Country Link
US (2) US12383556B2 (pl)
EP (2) EP3972603B1 (pl)
JP (2) JP7765970B2 (pl)
KR (1) KR20220011652A (pl)
CN (1) CN113811301A (pl)
AU (2) AU2020278236B2 (pl)
BR (1) BR112021023110A2 (pl)
CA (1) CA3137271A1 (pl)
CL (1) CL2021003034A1 (pl)
DK (1) DK3972603T3 (pl)
ES (1) ES3004516T3 (pl)
FI (1) FI3972603T3 (pl)
HR (1) HRP20241584T1 (pl)
HU (1) HUE069020T2 (pl)
IL (1) IL287745B1 (pl)
LT (1) LT3972603T (pl)
MX (1) MX2021014161A (pl)
PL (1) PL3972603T3 (pl)
PT (1) PT3972603T (pl)
RS (1) RS66195B1 (pl)
SI (1) SI3972603T1 (pl)
TW (1) TWI857060B (pl)
WO (1) WO2020234781A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3972603T3 (pl) 2019-05-23 2025-02-03 Novartis Ag Sposoby leczenia zespołu sjögrena przy użyciu inhibitora kinazy tyrozynowej brutona
WO2022162513A1 (en) * 2021-01-26 2022-08-04 Novartis Ag Pharmaceutical composition
EP4395779A1 (en) 2021-09-03 2024-07-10 Novartis AG Lou064 for treating multiple sclerosis
MX2024007354A (es) 2021-12-14 2024-06-28 Novartis Ag Metodos de tratamiento usando lou064.
TW202342048A (zh) 2022-02-28 2023-11-01 瑞士商諾華公司 使用lou064治療化膿性汗腺炎之方法
KR102875105B1 (ko) 2023-04-03 2025-10-21 주식회사 사이알바이오 재조합 세마포린 4d 차단항체를 유효성분으로 포함하는 쇼그렌 증후군 예방 또는 치료용 약학 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1448205T1 (sl) 2001-10-05 2011-07-29 Zalicus Inc Kombinacije za zdravljenje imunoinflamatornih motenj
US9512084B2 (en) 2013-11-29 2016-12-06 Novartis Ag Amino pyrimidine derivatives
PE20181074A1 (es) 2015-12-16 2018-07-04 Boehringer Ingelheim Int Compuestos heteroaromaticos como inhibidores de btk
JP6916185B2 (ja) 2016-01-13 2021-08-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Btk阻害剤としてのイソキノロン類
US10874741B2 (en) 2017-08-28 2020-12-29 Spectrix Therapeutics, LLC Compound to treat Sjogren's syndrome
CN111263771A (zh) 2017-11-03 2020-06-09 诺华股份有限公司 用于治疗干燥综合征的抗cd40抗体
TWI694995B (zh) 2017-11-06 2020-06-01 美商美國禮來大藥廠 Btk抑制劑化合物
PL3972603T3 (pl) 2019-05-23 2025-02-03 Novartis Ag Sposoby leczenia zespołu sjögrena przy użyciu inhibitora kinazy tyrozynowej brutona

Also Published As

Publication number Publication date
EP4442321A2 (en) 2024-10-09
TWI857060B (zh) 2024-10-01
RS66195B1 (sr) 2024-12-31
CA3137271A1 (en) 2020-11-26
WO2020234781A1 (en) 2020-11-26
TW202110451A (zh) 2021-03-16
AU2020278236A1 (en) 2022-01-06
CN113811301A (zh) 2021-12-17
AU2025263830A1 (en) 2025-11-27
JP2025165957A (ja) 2025-11-05
BR112021023110A2 (pt) 2022-04-12
PT3972603T (pt) 2024-11-26
DK3972603T3 (da) 2024-12-02
US12383556B2 (en) 2025-08-12
AU2020278236B2 (en) 2025-08-07
JP7765970B2 (ja) 2025-11-07
LT3972603T (lt) 2024-12-10
ES3004516T3 (en) 2025-03-12
EP3972603A1 (en) 2022-03-30
FI3972603T3 (fi) 2024-12-04
CL2021003034A1 (es) 2022-09-09
AU2020278236A8 (en) 2022-04-28
HRP20241584T1 (hr) 2025-01-31
HUE069020T2 (hu) 2025-02-28
SI3972603T1 (sl) 2025-02-28
KR20220011652A (ko) 2022-01-28
MX2021014161A (es) 2022-01-04
IL287745B1 (en) 2025-10-01
EP3972603B1 (en) 2024-09-04
IL287745A (en) 2021-12-01
US20220175772A1 (en) 2022-06-09
JP2022533968A (ja) 2022-07-27
EP4442321A3 (en) 2025-01-01
US20250339428A1 (en) 2025-11-06

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