SI3445354T1 - Estri azelainske kisline pri zdravljenju inzulinske rezistence - Google Patents

Estri azelainske kisline pri zdravljenju inzulinske rezistence

Info

Publication number
SI3445354T1
SI3445354T1 SI201731210T SI201731210T SI3445354T1 SI 3445354 T1 SI3445354 T1 SI 3445354T1 SI 201731210 T SI201731210 T SI 201731210T SI 201731210 T SI201731210 T SI 201731210T SI 3445354 T1 SI3445354 T1 SI 3445354T1
Authority
SI
Slovenia
Prior art keywords
treatment
acid esters
insulin resistance
azelaic acid
azelaic
Prior art date
Application number
SI201731210T
Other languages
English (en)
Inventor
Robert T. Streeper
Elzbieta Izbicka
Original Assignee
New Frontier Labs, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New Frontier Labs, Llc filed Critical New Frontier Labs, Llc
Publication of SI3445354T1 publication Critical patent/SI3445354T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
SI201731210T 2016-04-20 2017-04-19 Estri azelainske kisline pri zdravljenju inzulinske rezistence SI3445354T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662325381P 2016-04-20 2016-04-20
PCT/US2017/028417 WO2017184767A1 (en) 2016-04-20 2017-04-19 Azelaic acid esters in the treatment of insulin resistance
EP17786579.7A EP3445354B8 (en) 2016-04-20 2017-04-19 Azelaic acid esters in the treatment of insulin resistance

Publications (1)

Publication Number Publication Date
SI3445354T1 true SI3445354T1 (sl) 2022-10-28

Family

ID=60088670

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201731210T SI3445354T1 (sl) 2016-04-20 2017-04-19 Estri azelainske kisline pri zdravljenju inzulinske rezistence

Country Status (19)

Country Link
US (3) US10251857B2 (sl)
EP (2) EP3445354B8 (sl)
JP (2) JP7072762B2 (sl)
KR (1) KR102233912B1 (sl)
CN (1) CN109195597B (sl)
AU (2) AU2017253088B2 (sl)
CA (1) CA3021516C (sl)
DK (1) DK3445354T3 (sl)
ES (1) ES2925775T3 (sl)
HR (1) HRP20220988T1 (sl)
HU (1) HUE059844T2 (sl)
LT (1) LT3445354T (sl)
NZ (1) NZ746669A (sl)
PL (1) PL3445354T3 (sl)
PT (1) PT3445354T (sl)
RS (1) RS63558B1 (sl)
SG (1) SG11201808367UA (sl)
SI (1) SI3445354T1 (sl)
WO (1) WO2017184767A1 (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3445354T1 (sl) * 2016-04-20 2022-10-28 New Frontier Labs, Llc Estri azelainske kisline pri zdravljenju inzulinske rezistence
IL295663A (en) * 2020-02-19 2022-10-01 New Frontier Labs Llc Azelaic acid esters in the treatment or prevention of hyperlipidemia and related conditions

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2426683A1 (de) * 1974-06-01 1975-12-18 Boehringer Mannheim Gmbh Biguanide und verfahren zu deren herstellung
US5594015A (en) * 1994-06-22 1997-01-14 Regents Of The University Of California Thiazolidine derivatives for the treatment of psoriasis
WO2001012786A1 (en) * 1999-08-16 2001-02-22 Human Genome Sciences, Inc. Retinoid receptor interacting polynucleotides, polypeptides, and antibodies
US6627223B2 (en) * 2000-02-11 2003-09-30 Eurand Pharmaceuticals Ltd. Timed pulsatile drug delivery systems
ATE454895T1 (de) * 2001-08-13 2010-01-15 Univ Yale Verfahren zur induktion einer selektiv unterdrückten immunantwort
US7149574B2 (en) * 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
US20080051373A1 (en) * 2003-07-31 2008-02-28 The Board Of Regents Of The University Of Texas System Parenteral preparations of GI-safer phospholipid-associated anti-inflammatories and methods of preparation and use
WO2006074379A2 (en) 2005-01-07 2006-07-13 Azaya Therapeutics, Inc. Methods and compositions involving esters of azelaic acid and other dicarboxylic acids
US8440217B1 (en) * 2005-06-15 2013-05-14 Mawaheb M. EL-Naggar Method and system with contact lens product for treating and preventing adverse eye conditions
EP1909766B1 (en) * 2005-07-28 2016-03-16 Shire LLC PHARMACEUTICAL FORMULATIONS/COMPOSITIONs OF GUANFACINE SUITABLE FOR SINGLE DAILY DOSE
US7713929B2 (en) * 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
US8093017B2 (en) * 2005-12-07 2012-01-10 Siemens Heathcare Diagnostics Inc. Detection of soluble adiponectin receptor peptides and use in diagnostics and therapeutics
ES2390620T3 (es) * 2008-03-10 2012-11-14 Nestec S.A. Ácidos dicarboxílicos de cadena mediana y sus derivados y trastornos metabólicos
US20090326069A1 (en) * 2008-06-30 2009-12-31 Bltn, Llc Azelaic acid ester compositions and methods for diagnosing and treating tissue conditions using azelaic acid ester compositions and proteinaceous biomarkers
US20120251525A1 (en) * 2009-06-30 2012-10-04 Streeper Robert T Method of utilizing azelaic acid esters to modulate communications mediated by biological molecules
US9023887B2 (en) * 2011-04-15 2015-05-05 University of Pittsburgh—of the Commonwealth System of Higher Education Lipase inhibitors for the treatment of pancreatitis and organ failure
KR101593539B1 (ko) * 2015-07-03 2016-02-15 고려대학교 산학협력단 지방조직 중성지질 분해 효능을 가지는 아젤라산 조성물
SI3445354T1 (sl) * 2016-04-20 2022-10-28 New Frontier Labs, Llc Estri azelainske kisline pri zdravljenju inzulinske rezistence

Also Published As

Publication number Publication date
CA3021516C (en) 2024-02-20
HUE059844T2 (hu) 2023-01-28
RS63558B1 (sr) 2022-10-31
JP7072762B2 (ja) 2022-05-23
WO2017184767A1 (en) 2017-10-26
AU2022203809B2 (en) 2024-02-22
US20210260014A1 (en) 2021-08-26
EP4085907A1 (en) 2022-11-09
SG11201808367UA (en) 2018-10-30
AU2017253088B2 (en) 2022-04-28
AU2022203809A1 (en) 2022-06-23
PT3445354T (pt) 2022-08-25
US20170304252A1 (en) 2017-10-26
LT3445354T (lt) 2022-09-12
HRP20220988T1 (hr) 2022-11-11
ES2925775T3 (es) 2022-10-19
JP7088460B2 (ja) 2022-06-21
JP2021091709A (ja) 2021-06-17
JP2019515895A (ja) 2019-06-13
CN109195597A (zh) 2019-01-11
US20190167627A1 (en) 2019-06-06
EP3445354A1 (en) 2019-02-27
EP3445354B1 (en) 2022-05-25
US11026912B2 (en) 2021-06-08
KR102233912B1 (ko) 2021-03-29
EP3445354B8 (en) 2022-07-06
NZ746669A (en) 2022-10-28
US10251857B2 (en) 2019-04-09
DK3445354T3 (da) 2022-08-29
PL3445354T3 (pl) 2022-09-19
CA3021516A1 (en) 2017-10-26
AU2017253088A1 (en) 2018-10-18
CN109195597B (zh) 2021-08-24
EP3445354A4 (en) 2020-01-01
KR20180133914A (ko) 2018-12-17

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